A. Clara Drenth‐van Maanen

ORCID: 0000-0003-1381-1227
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About
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Research Areas
  • Pharmaceutical Practices and Patient Outcomes
  • Health Systems, Economic Evaluations, Quality of Life
  • Medication Adherence and Compliance
  • Patient Safety and Medication Errors
  • Pharmacy and Medical Practices
  • Pharmaceutical studies and practices
  • Pharmacovigilance and Adverse Drug Reactions
  • Dialysis and Renal Disease Management
  • Chronic Disease Management Strategies
  • Chronic Kidney Disease and Diabetes
  • Electronic Health Records Systems
  • Blood Pressure and Hypertension Studies
  • Information Systems Theories and Implementation
  • Data Quality and Management
  • Dutch Social and Cultural Studies
  • Global Health Care Issues
  • Patient Satisfaction in Healthcare
  • Healthcare cost, quality, practices
  • Primary Care and Health Outcomes
  • Perfectionism, Procrastination, Anxiety Studies

University Medical Center Utrecht
2009-2022

Utrecht University
2010-2022

University Hospital Heidelberg
2021

Heidelberg University
2021

GGD Amsterdam
2014

Catharina Ziekenhuis
2008

Radboud University Nijmegen
2008

Abstract Objective To examine the effect of optimising drug treatment on related hospital admissions in older adults with multimorbidity and polypharmacy admitted to hospital. Design Cluster randomised controlled trial. Setting 110 clusters inpatient wards within university based hospitals four European countries (Switzerland, Netherlands, Belgium, Republic Ireland) defined by attending doctors. Participants 2008 (≥70 years) (≥3 chronic conditions) (≥5 drugs used long term). Intervention...

10.1136/bmj.n1585 article EN cc-by-nc BMJ 2021-07-13

Polypharmacy poses threats to patients' health. The Systematic Tool Reduce Inappropriate Prescribing (STRIP) is a drug optimization process for conducting medication reviews in primary care. To effectively and efficiently incorporate this method into daily practice, the STRIP Assistant—a decision support system that aims assist physicians with pharmacotherapeutic analysis of medical records—has been developed. It generates context-specific advice based on clinical guidelines. aim study was...

10.1007/s40266-015-0270-0 article EN cc-by-nc Drugs & Aging 2015-05-29

Abstract Inappropriate prescribing is a major health care issue, especially regarding older patients on polypharmacy. Multiple implicit and explicit tools have been developed to improve prescribing, but these hardly ever used in combination. The Systematic Tool Reduce Prescribing (STRIP) combines with the Screening Alert physicians Right Treatment of Older People's potentially inappropriate Prescriptions criteria has shared decision‐making patient as critical step. This article describes...

10.1111/jep.12787 article EN Journal of Evaluation in Clinical Practice 2017-08-04

The Cockcroft-Gault (CG), the Modification of Diet in Renal Disease (MDRD) and CKD-EPI (Chronic Kidney Epidemiology Collaboration) formulae are often used to estimate glomerular filtration rate (GFR). objective was determine best method for estimating GFR older adults.A cross-sectional study conducted at geriatric wards two hospitals Netherlands. Patients aged 70 years or above with an estimated (e)GFR below 60 ml min⁻¹ 1.73 m⁻² were included. CG, CG calculated ideal bodyweight (IBW), MDRD...

10.1111/bcp.12199 article EN British Journal of Clinical Pharmacology 2013-06-26

To determine the prevalence, determinants, and potential clinical relevance of adherence with Dutch dosing guideline in patients impaired renal function at hospital discharge.Retrospective cohort study between January 2007 July 2011.Academic teaching Netherlands.Patients an estimated glomerular filtration rate (eGFR) 10-50 ml/min/1.73 m(2) discharge prescribed one or more medicines which dose is dependent.The prevalence was investigated, influence possible such as reporting eGFR severity...

10.1371/journal.pone.0128237 article EN cc-by PLoS ONE 2015-06-08

The use of multiple drugs by patients increases the risk medical problems. Clinical decision support could assist general practitioners with prescribing but is underused. This article aims to investigate attitudes towards using systems. A survey was distributed among 500 Dutch practitioners. Virtually all 184 respondents indicated having a clinical information system, while only 21 percent plug-in; this correlated their formularies. Only one formularies number recognized underprescription...

10.1177/1460458212472333 article EN Health Informatics Journal 2013-11-19

Polypharmacy is becoming increasingly common and all doctors must be prepared to manage it competently.The aim of this project evaluate the feasibility use a novel gamification-based teaching intervention on polypharmacy among undergoing advanced geriatric training. Among others, one learning goals for students was able describe adherence medication.Electronic questionnaire sent third session "evidence-based medicine in geriatrics" postgraduate course geriatrics European Academy Medicine...

10.1007/s40520-021-01933-9 article EN cc-by Aging Clinical and Experimental Research 2021-07-18

Abstract Background Identifying patients at high risk of drug‐related hospital admission (DRA) may help to efficiently target preventive interventions. We developed a score predict DRAs in older with multimorbidity and polypharmacy. Methods used participants from the multicenter European OPERAM trial (“Optimising PharmacothERapy Mutlimorbid Elderly”). assessed association between easily identifiable predictors 1‐year by univariable logistic regression. Variables p ‐value< 0.20 were taken...

10.1111/jgs.17667 article EN cc-by-nc-nd Journal of the American Geriatrics Society 2022-01-22

Multimorbidity and polypharmacy are risk factors for drug-related hospital admissions (DRAs) in the ageing population. DRAs caused by medication errors (MEs) considered potentially preventable. The STOPP/START criteria were developed to detect potential MEs older people.

10.1007/s40264-022-01237-5 article EN cc-by-nc Drug Safety 2022-11-01
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