A5000953027- Autoimmune Bullous Skin Diseases
- Inflammatory Myopathies and Dermatomyositis
- Eosinophilic Disorders and Syndromes
- Drug-Induced Adverse Reactions
- Oral Health Pathology and Treatment
- Dermatology and Skin Diseases
- Skin and Cellular Biology Research
- Cutaneous lymphoproliferative disorders research
- Dermatological and Skeletal Disorders
- Immunodeficiency and Autoimmune Disorders
- Nonmelanoma Skin Cancer Studies
- Autoimmune and Inflammatory Disorders Research
- Nail Diseases and Treatments
- Skin Diseases and Diabetes
- Tattoo and Body Piercing Complications
- Cancer Immunotherapy and Biomarkers
- Psoriasis: Treatment and Pathogenesis
- Dermatologic Treatments and Research
- Urticaria and Related Conditions
- Contact Dermatitis and Allergies
- Autoimmune and Inflammatory Disorders
- Blood groups and transfusion
- Hereditary Neurological Disorders
- Dupuytren's Contracture and Treatments
- Venomous Animal Envenomation and Studies
Inserm
2017-2022
Hôpital Bichat-Claude-Bernard
2015-2022
Hôpital Saint-Louis
2015-2022
Assistance Publique – Hôpitaux de Paris
2016-2020
Université Paris Cité
2017-2020
Institut de recherche Saint-Louis
2019-2020
Université Claude Bernard Lyon 1
2019-2020
University of London Institute in Paris
2020
Délégation Paris 7
2017-2019
Sorbonne Paris Cité
2017-2019
Abstract Background Dystrophic epidermolysis bullosa pruriginosa (DEB‐Pr) is a rare subtype of hereditary bullosa, with poorly understood pathogenesis and no satisfactory treatment. Objectives To assess the clinical biological features, genetic basis therapeutic management, to better characterize this genodermatosis. Methods We have conducted retrospective study, reviewing presentation, diagnosis, immunohistopathological findings characteristics management patients dystrophic pruriginosa....
Cutaneous involvement of chronic graft-versus-host disease (cGVHD) has a wide range manifestations including lichenoid form with currently assumed mixed Th1/Th17 signature and sclerotic Th1 signature. Despite substantial heterogeneity innate adaptive immune cells recruited to the skin different clinical manifestations, treatment depends mainly on severity relies systemic, high-dose glucocorticoids alone or in combination calcineurin inhibitor. We performed first study using RNA sequencing...
Although numerous pathologies are associated with abnormal skin deposits, these remain poorly described, as accurate characterization continues to present a challenge for dermatologists. Their submicrometer size well their diverse chemistry require various tools. We aim exemplify of endogenous and exogenous deposits in some selected diseases using different physico-chemical techniques. begin presentation deposits. then those our results which show variety structure, location chemical...
Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes that important for antibacterial immunity and may have regulatory roles. MAIT decreased during SLE. However, their frequencies phenotype not been investigated in DM. We studied cell DM patients with active inactive disease (after treatment).Peripheral blood flow cytometry analysis of was compared between (n = 22), SLE 10), psoriasis 7) atopic dermatitis 5) patients, healthy controls 19).A dramatic decrease circulating...
In patients with ipilimumab (IPI)-refractory melanoma, the anti-programmed cell death proteins 1 (PD1s) nivolumab (NIV) and pembrolizumab (PEM) are considered to be a new standard of treatment. Few data available on anti-PD1 safety in who develop IPI-related severe adverse events (AEs) (grade≥3). The aim this study was compare efficacy previous toxicity IPI versus those showing moderate no AEs. This single institution-based observational included all treated (PEM or NIV) previously for...
In most patients pseudoxanthoma elasticum (PXE) manifests with yellowish cutaneous papules and dermal elastorrhexis on skin biopsy. a small number of cases there are no manifestations clinical examination, establishing diagnosis PXE in such is challenging. High-frequency ultrasonography (HFUS) may be use predicting areas that would yield biopsy specimen positive for elastorrhexis.To describe characteristics clinically visible using HFUS, to evaluate its relevance diagnosis.HFUS was performed...
Puffy hand syndrome develops after long-term intravenous drug addiction. It is characterized by a nonpitting edema, affecting the dorsal side of fingers and hands with puffy aspect. Frequency severity complications this are rarely reported. Local infectious such as cellulitis can be severe enable diagnosis. Herein, we report case 41-year-old man who went to emergency department for abdominal pain, fever, bullous lesions legs arms edema. Bacteriologic examination closed lesion evidenced...
Skin reactions are well described complications of tattooing, usually provoked by red inks. Chemical characterizations these inks based on limited subjects and techniques. This study aimed to determine the organic inorganic composition using X-ray fluorescence spectroscopy (XRF), absorption (XANES) Raman spectroscopy, in a cohort patients with cutaneous hypersensitivity tattoo. A retrospective multicenter was performed, including 15 diagnosed skin tattoos. Almost half developed black XRF...