A5044738030- CNS Lymphoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Advanced biosensing and bioanalysis techniques
- Microfluidic and Capillary Electrophoresis Applications
- Brain Metastases and Treatment
- Nanopore and Nanochannel Transport Studies
- Immunotherapy and Immune Responses
- Advanced Chemical Sensor Technologies
- Cancer, Hypoxia, and Metabolism
- Liver Disease Diagnosis and Treatment
- RNA modifications and cancer
- Fungal Biology and Applications
- Analytical Chemistry and Chromatography
- Colorectal Cancer Surgical Treatments
- Pharmacological Effects of Natural Compounds
- Advanced Vision and Imaging
- Cancer-related molecular mechanisms research
- Colorectal Cancer Treatments and Studies
- Advanced Aircraft Design and Technologies
- Ginseng Biological Effects and Applications
- Patient Dignity and Privacy
- Extracellular vesicles in disease
Fudan University Shanghai Cancer Center
2009-2025
Wenzhou Medical University
2022-2025
Capital Medical University
2015-2025
Beijing Tian Tan Hospital
2018-2025
Beihang University
2025
Hunan University
2022-2025
Xuzhou Medical College
2024-2025
Hangzhou Medical College
2024
Zhejiang Provincial People's Hospital
2024
Northwestern Polytechnical University
2024
Liquiritigenin (LQ) is a flavanone extracted from glycyrrhizae. Previous studies have demonstrated that LQ possesses antimigration properties in HELA and A549 cells. The present research, as an extension of our earlier ones, investigated whether can enhance the antiinvasion effect cis-diamine dichloroplatinum (CDDP) B16F10 melanoma cell. data indicated (25, 50, 100, 200 μM) combined with CDDP (2 significantly reduced cell viability compared to μM)-treated only. different doses suppressed...
The aim of this prospective, single-arm phase II trial was to confirm the safety and efficacy neoadjuvant chemotherapy (NAC) using oxaliplatin plus capecitabine (CapOX) for patients with operable locally advanced colon cancer (CC).Patients computed tomography-defined T4 or lymph node-positive CCs were enrolled. After radiological staging, treated at least 2 cycles NAC consisting 130 mg/m2 on d 1, 1,000 twice daily 14 every 3 weeks, followed by surgery, then rest adjuvant chemotherapy....
Primary central nervous system lymphoma (PCNSL) is a specific subtype of non-Hodgkin that highly invasive and confined to the (CNS). The vast majority PCNSLs are diffuse large B-cell lymphomas (DLBCLs). PCNSL heterogeneous disease, its pathogenesis has not yet been fully elucidated. Further studies needed guide individualized therapy improve prognosis.In this study, we detected 1) expression p-AKT, p-mTOR, p-S6 p-4E-BP1 by immunohistochemistry (IHC) Western blotting, 2) mRNA real-time qPCR...
151 Background: Anti-angiogenic drugs combined with chemotherapy could bring good clinical benefit to patients (pts) mCRC, but the efficacy in pts RAS mutant mCRC was limited. Fruquintinib is a highly selective oral inhibitor of vascular endothelial growth factor receptors (VEGFRs -1, -2, and -3) approved for previously treated mCRC. Our study explore safety fruquintinib FOLFIRI/mFOLFOX6 second line treatment RAS-mutant (NCT05634590). Methods: Eligible histologically confirmed who had...
ABSTRACT Neural radiation field (NeRF) has been widely used in the of talking portrait synthesis. However, inadequate utilisation audio information and spatial position leads to inability generate images with high audio‐lip consistency realism. This paper proposes a novel tri‐plane dynamic neural (Tri‐NeRF) that employs an implicit study impacts on facial movements. Specifically, Tri‐NeRF propose offset network (TPO‐Net) positions three 2D planes guided by audio. allows for sufficient...
Liquiritigenin (LQ) is a flavanone extracted from Glycyrrhizae, which has multiple biological effects, such as antiinflammation and anticancer. This study the first to investigate effect of LQ on migration human lung adenocarcinoma A549 cells in vitro. First, exhibited inhibitory effects adhesion absence cytotoxicity. Gelatin zymography Western blot analysis showed that significantly reduced expression promatrix metalloproteinase-2 (proMMP-2) terms both activity protein level. Second,...
Rationale: Static assembled multivalent DNA nanotheranostics system have encountered some bottleneck problems in cancer imaging and therapy, such as poor penetration high immunogenicity.Herein, we proposed an acidic tumor microenvironment triggered assembly of activatable nanodevice, called "three-arm aptamer nanoclaw" (TA-aptNC), from three pH-responsive aptamer-decorated monomers (pH-aptDMs) to facilitate their functions therapy. Methods:The activated TA-aptNC was constructed by situ...
It has been indicated that abnormal glucose metabolism mediated by hypoxia-inducible factor 1α (HIF-1α) played an essential role in the development of solid tumor. However, there were rare studies about them primary central nervous system lymphoma (PCNSL).To investigate protein levels HIF-1α, transporter 1 (GLUT1), and hexokinase 2 (HK2) PCNSL whether their are associated with prognostic factors.Expression GLUT1, HK2 39 tumor tissues was evaluated immunohistochemical stainning. The...
// Changhua Zhuo 1, 2, * , Qingguo Li Yuchen Wu 1 Yiwei Jia Nie 3 Dawei Junjie Peng Lian Bin Guoxiang Cai Xinxiang Sanjun Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Oncology, Medical College, University, 200032, People’s Republic China 2 Surgical Fujian Provincial Hospital, Teaching Hospital Fuzhou 350014, Key Laboratory Molecular Virology & Immunology, Unit Institut Pasteur Shanghai, Institutes for Biological Sciences, Chinese Academy 200031, These...
The properties of nanopipettes largely rely on the materials introduced onto their inner walls, which allow for a vast extension sensing capabilities. challenge simultaneously enhancing sensitivity and selectivity pH remains, hindering practical applications. Herein, we report insulin-modified with excellent response performances, were prepared by introducing insulin walls via two-step reaction involving silanization amidation. intensity based ion current rectification was significantly...