- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Hemodynamic Monitoring and Therapy
- Adipokines, Inflammation, and Metabolic Diseases
- Anesthesia and Sedative Agents
- Optical Imaging and Spectroscopy Techniques
- Airway Management and Intubation Techniques
- Cardiac Valve Diseases and Treatments
- Tracheal and airway disorders
- Intensive Care Unit Cognitive Disorders
- Cardiovascular Function and Risk Factors
- Pain Mechanisms and Treatments
- Cardiac Structural Anomalies and Repair
- Shoulder Injury and Treatment
- Pain Management and Treatment
- Cardiac tumors and thrombi
- Cardiac Arrest and Resuscitation
- Nausea and vomiting management
- Immune Response and Inflammation
- Neuropeptides and Animal Physiology
- Cardiac Imaging and Diagnostics
- Antioxidant Activity and Oxidative Stress
- Thermoregulation and physiological responses
- Anesthesia and Neurotoxicity Research
- S100 Proteins and Annexins
Pusan National University Hospital
2016-2024
Pusan National University
2011-2024
Pusan National University Yangsan Hospital
2015-2018
Yonsei University
2006-2010
Purpose: This study aimed to evaluate the impact of declining surgical residency program enrollment on patient care and outcomes in colorectal cancer surgeries.Methods: retrospective observational included 676 patients (410 males; median age: 69 years) who underwent surgery at Pusan National University Hospital between January 2018 June 2024. Patients were divided into Group A (before December 31, 2023; with residents) B (after 1, 2024; without residents). All surgeries performed by a single...
Bone remodeling plays an important role in the bone healing process; for example, following fracture. The relative ratio of receptor activator nuclear factor kappa B ligand (RANKL)/ osteoprotegerin (OPG) controls osteoclast differentiation, thereby playing a pivotal regulation remodeling. Propofol, widely used anesthetic agent orthopedic procedures, is considered to possess potential antioxidant properties owing its structural similarity α-tocopherol. Antioxidants are known enhance healing....
Thoracic epidural anesthesia (TEA) exacerbates hypotension due to peripheral vasodilator effects following the use of general anesthetics. This study aimed compare hemodynamic changes caused by three different concentrations ropivacaine and evaluate performance stroke-volume variation (SVV) central venous pressure (CVP) during TEA with anesthesia.A total 120 patients were administered 8 mL solution via injection, randomization into one groups based on concentration in solution: 0.75%,...
Background: Patient-controlled epidural analgesia (PCEA) is known to provide good postoperative in many types of surgery including laparoscopic surgery.However, no study has compared PCEA with patient-controlled intravascular (PCIA) radical prostatectomy (LARP).In this study, the efficacy and side effects PCIA after LARP were compared.Methods: Forty patients undergoing randomly divided into two groups: 1) a group, treated 0.2% ropivacaine 3 ml 0.1 mg morphine bolus; 2) oxycodone 1 nefopam...
Among the various pain-related diseases that can be encountered at clinic, there is a neuropathic pain difficult to treat. Numerous methods have been proposed treat pain, such as taking medication, nerve block with lidocaine, or neurolysis alcohol phenol. Recently, method of perineural injection using dextrose instead lidocaine was proposed. This study designed compare effects therapy (PIT) buffered 5% 0.5% on pain.
Background: Spinal anesthesia-induced hypotension (SAH) frequently occurs in older patients, many of whom have mild left ventricular (LV) diastolic dysfunction, often asymptomatic at rest. This study investigated the association between preoperative echocardiographic measurements and SAH patients with LV dysfunction. Methods: We conducted a retrospective observational using data from electronic medical records. The ≥ 65 years old who underwent spinal anesthesia for urologic surgery January...
Postherpetic neuralgia (PHN) is usually managed pharmacologically. It not uncommon for patients with chronic kidney disease (CKD) to suffer from PHN. difficult prescribe a sufficient dose of anticonvulsants intractable pain because the decreased glomerular filtration rate. If neural blockade and pulsed radiofrequency ablation provide only short-term amelioration pain, spinal cord stimulation (SCS) low level evidence may be used as last resort. This study was done evaluate efficacy in...
The pentadecapeptide BPC-157 has been shown to have anti-inflammatory and wound healing effects on multiple target tissues organs. Peptides potent periodontal in rats with periodontitis. Few studies investigated the effect of pain after dental procedures or oral surgeries. purpose present study was investigate antinociceptive postoperative incisional rats.Sprague-Dawley were randomly divided into five groups: control (saline same volume), BPC10 (10 µg/kg BPC-157), BPC20 (20 BPC40 (40...
Background Carotid endarterectomy (CEA) has been performed under regional and general anesthesia (GA). The versus local for carotid surgery study compared the two techniques concluded that there was no difference in perioperative outcomes. However, since this trial, new sedative agents have introduced devices improve delivery of (RA) developed. primary purpose pilot to compare intraoperative hemodynamic stability postoperative outcomes between GA ultrasound-guided superficial cervical plexus...
Background:The purpose of this study was to investigate the effect general anesthesia on microvascular reactivity and tissue oxygen saturation (StO2) using near-infrared spectroscopy in conjunction with vascular occlusion tests (VOT).Age-related changes reactivity, that is, capacity capillary recruitment, were examined.Methods: This prospective observational performed 60 patients without comorbidities who underwent elective surgery under anesthesia.Baseline StO2 thenar eminence,...
We report obstruction of the left ventricle outflow tract (LVOT) caused by cardiac myxoma that was misidentified as an accessory mitral valve tissue preoperatively. A 65-year-old woman presented with chest discomfort persisted for 7 days. Transthoracic echocardiography (TTE) revealed a mobile, low-echogenic, balloon-shaped mass attached to anterior leaflet and papillary muscle, which suspected be tissue. Because LVOT it could result in hemodynamic instability, emergency operation performed....
Proteus syndrome (PS) is a rare congenital hamartomatous disorder with multisystem involvement. PS shows highly clinical variability due to overgrowth of the affected areas, and several features can make anesthetic management challenging. Little known about airway problem associated anesthesia in patients. An 11-year-old girl was scheduled for ear surgery under general anesthesia. She had complicating intubation including facial asymmetry disproportion, abnormal teeth, limitation neck...
BACKGROUND Robot-assisted radical prostatectomy (RARP) is becoming an increasingly common method for treatment of prostate cancer. This study aimed to compare outcomes estimated blood loss and postoperative pain, determined by patient-controlled analgesia (PCA), between RARP standard laparoscopic -prostatectomy (LRP). MATERIAL AND METHODS We enrolled 57 patients who had localized cancer (28 in RARP, 29 LRP). Primary were (EBL) measured gravimetric gauze visual estimation suction bottle, PCA...
A nasogastric tube (NGT) is commonly inserted into patients undergoing abdominal surgery to decompress the stomach during or after surgery. However, for anatomic reasons, insertion of NGTs anesthetized and intubated may be challenging. We hypothesized that use a exchanger NGT could increase success rate reduce complications. One hundred adult patients, aged 20-70 years, who were scheduled gastrointestinal surgeries with general anesthesia enrolled in our study. The randomly allocated...
Background: Microcirculatory disturbances are typically most severe during cardiopulmonary bypass (CPB), which occurs cardiac surgeries. If microvascular reactivity compensates for microcirculatory CPB, tissue hypoxemia can be minimized. The primary aim of this study was to assess whether CPB could predict major adverse events (MAE) after surgery.Methods: This prospective observational included 115 patients who underwent elective on-pump A vascular occlusion test (VOT) with near-infrared...
A 43-year-old woman was admitted due to fever, chills, and headache for several days diagnosed as infective endocarditis. Intraoperative transesophageal echocardiography (TEE) examination confirmed severe aortic stenosis showed relatively fresh 1.5 cm vegetation on the left coronary cusp of valve (AV) with frequent diastolic prolapse into root. This mobile partially occluded ostium, but it did not cause cardiac failure. TEE be in good position across AV. The AV replacement removal mitral...
Background: We investigated the effects of sevoflurane exposure on expression matrix metalloproteinase (MMP), and ablation natural killer group 2, member D (NKG2D) ligands (UL16-binding proteins 1–3 major histocompatibility complex class I chain-related molecules A/B), (NK) cell-mediated cytotoxicity in breast cancer cells.Methods: Three human cell lines (MCF-7, MDA-MB-453, HCC-70) were incubated with 0 (control), 600 (S6), or 1200 μM (S12) for 4 h. The gene NKG2D their protein surfaces...