- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Knee injuries and reconstruction techniques
- Management of metastatic bone disease
- Sarcoma Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical site infection prevention
- Hip and Femur Fractures
- Shoulder Injury and Treatment
- Orthopedic Surgery and Rehabilitation
- Venous Thromboembolism Diagnosis and Management
- Lymphatic System and Diseases
- Cancer Immunotherapy and Biomarkers
- Foot and Ankle Surgery
- Bone and Joint Diseases
- Anesthesia and Pain Management
- Streptococcal Infections and Treatments
- Cancer Cells and Metastasis
- Inflammatory Bowel Disease
- Patient Satisfaction in Healthcare
- MRI in cancer diagnosis
- Blood transfusion and management
- Image and Video Quality Assessment
Mayo Clinic in Arizona
2012-2025
Mayo Clinic
2014-2024
University of California, San Diego
2023-2024
University of Rhode Island
2024
Cleveland Clinic Florida
2022
WinnMed
2020-2021
University College London
2019
Istanbul University
2019
Lawson Health Research Institute
2018
Mayo Clinic in Florida
2018
For patients undergoing 2-stage exchange for the treatment of periprosthetic joint infection (PJI) following total knee arthroplasty, long-term risk reinfection and mechanical failure clinical outcomes are not well known. The purpose our study was to determine results PJI arthroplasty.We identified 245 knees that had undergone arthroplasty were subsequently treated with due during period 1991 2006; cohort no prior PJI. Major, or 4 6 minor, Musculoskeletal Infection Society (MSIS) diagnostic...
Background: Total knee arthroplasty (TKA) with a rotating-hinge prosthesis is considered salvage procedure. While excellent immediate stability achieved, the historically high failure rate has tempered its use. The goal of this study was to determine clinical outcomes, radiographic results, and survivorship after TKA contemporary components. Methods: We identified 408 consecutive TKAs performed components for nononcologic indications from 2002 2012 at single academic institution. Two hundred...
Concurrent hip and spine pathologies can alter the biomechanics of spinopelvic mobility in primary total arthroplasty (THA). This study examines how differences pelvic orientation patients with fusions increase risk dislocation after THA.We identified 84 (97 THAs) between 1998 2015 who had undergone spinal fusion prior to THA. Patients were stratified into three groups depending on length lumbar whether or not sacrum was involved. Mean age 71 years (40 87) 54 (56%) female. The mean body mass...
Limited data exist that show the long-term risks of reinfection and mechanical failure with a contemporary 2-stage exchange protocol for periprosthetic joint infection following total hip arthroplasty. The purpose this study was to determine rates after arthroplasty.We identified 164 hips (162 patients) arthroplasty between 1991 2006 treated no prior treatment infection. With regard Musculoskeletal Infection Society diagnostic criteria, at least 1 major criterion or 4 6 minor criteria were...
Loss or absence of proximal femoral bone in revision total hip arthroplasty (THA) remains a significant challenge. While the main indication for use replacements (PFRs) is treatment malignant disease, they have valuable role THA loosening, fracture and infection patients with loss. Our aim was to determine clinical outcomes, implant survivorship, complications PFRs used indications other than malignancy.A retrospective review 44 who underwent using PFR between 2000 2013 undertaken. Their...
Disruption of the extensor mechanism after total knee arthroplasty (TKA) is debilitating, and reported results numerous reconstructive options have varied. We previously early 13 patients who underwent reconstruction with use Marlex mesh. The purpose current study was to assess in a larger cohort patients, an emphasis on survivorship mesh, clinical results, complications.During period 2000 2015 at single tertiary care academic institution, 77 (77 TKAs) mesh for disruption (27 quadriceps...
Metaphyseal fixation during revision total knee arthroplasty (TKA) is important, but potentially difficult when using historical designs of cone. Material and manufacturing innovations have improved the size shape cones which are available, simplified required bone preparation. In a large series, we assessed implant survivorship, radiological results, clinical outcomes new porous 3D-printed titanium metaphyseal featuring reamer-based system.We reviewed 142 TKAs in 139 patients 202 (134...
Background: Povidone-iodine (PI) irrigation is often used prior to wound closure in total joint arthroplasty, but there are limited reports evaluating its efficacy decreasing infections. The goal of this study was compare the rate any reoperation for infection (both superficial and deep) primary hip arthroplasty (THA) knee (TKA) among patients who did not receive PI closure. Methods: Using our institution’s registry, we identified 5,534 THA 6,204 TKA procedures performed from 2013 2017....
Background: Postoperative infection remains a major challenge in revision total hip arthroplasty (THA) and knee (TKA). Wound irrigation with dilute povidone-iodine (PI) solution has emerged as simple, inexpensive, potentially successful means of reducing postoperative infections. The aim this study was to assess its effectiveness following THA TKA in, our knowledge, the largest cohort date. Methods: Using institution’s joint registry, we identified 1,402 THAs 1,482 TKAs performed during...
Background: Some prior reports of total knee arthroplasty after high tibial osteotomy have shown rates aseptic loosening. As such, the goal this study was to analyze outcomes contemporary osteotomy, with particular emphasis on survivorship free from loosening, any revision, and reoperation; complications; radiographic results; clinical outcomes. Methods: We retrospectively reviewed 207 patients who underwent 231 arthroplasties using cemented prostheses 2000 2012 through our joint registry:...
Background: The periacetabular region is a common location for metastatic disease. Although large lytic acetabular defects are commonly treated with hip arthroplasty cemented component according to Harrington-style reconstruction, the use of highly porous uncemented tantalum components has been described. Currently, there no direct comparisons these reconstructive techniques. purpose this study was compare outcomes Harrington technique and reconstruction metastases. Methods: From 2 tertiary...
Aims The aim of this study was to determine the diagnostic accuracy α defensin (AD) lateral flow assay (LFA) and enzyme-linked immunosorbent (ELISA) tests for periprosthetic joint infection (PJI) in comparison conventional synovial white blood cell (WBC) count polymorphonuclear neutrophil percentage (PMN%) analysis. Methods Patients undergoing aspiration evaluation pain after total knee arthroplasty (TKA) or hip (THA) were considered inclusion. Synovial fluids from 99 patients (25 THA 74...
Background Bacteremia is sometimes observed in patients with prosthetic joint infection (PJI), and it associated a lower likelihood of control. However, the prevalence association bacteremia chronic PJI remain unknown. Questions/purposes (1) What percentage are diagnosed at time hospital admission before surgery for PJI? (2) clinical factors positive blood cultures? (3) To what degree cultures infection-free implant survival Methods This prospective study was conducted single academic...
Introduction: Contemporary failure etiologies of primary total hip arthroplasties (THAs) have not been precisely defined because heterogeneity referral practices. Methods: A single-institution registry 4,555 primary, noncemented THAs performed by subspecialty trained arthroplasty surgeons between 2000 and 2012 was analyzed. Only revision surgeries revisions that occurred after initially at the institution were included. Results: The estimated 10-year survivorships free from THA surgery,...
There is interest in novel synovial fluid biomarkers for the detection of periprosthetic joint infection (PJI). Here, we assessed diagnostic accuracy 23 simple or sophisticated hip knee detection. One hundred seven subjects were studied, 57 whom had aseptic failure (AF) and 50 PJI. The following tested using spectrophotometric assays, immunoassays, lateral flow tests, test strips: leukocyte count, monocyte percentage, lymphocyte neutrophil C-reactive protein (CRP), glucose, lactate,...
Background: Spinal anesthesia provides several benefits for patients undergoing total hip arthroplasty (THA) and knee (TKA), but historically comes at the cost of slow unpredictable return lower-extremity motor function related to use long-acting local anesthetics. In this prospective, double-blinded, randomized clinical trial we sought determine if an alternative anesthetic, mepivacaine, would allow more consistent compared with low-dose bupivacaine spinal during primary THA TKA. Methods:...
Background: Two-stage exchange is the most common form of treatment chronic infection following total hip arthroplasty (THA). We examined prevalence of, and risk factors associated with, instability 2-stage as well fate reimplanted prostheses that dislocated. Methods: Data on 515 THAs performed between 2000 2014 at a single institution were retrospectively reviewed. Risk for postoperative reoperations revisions analyzed. The impact dislocation these outcomes was evaluated well. mean age time...