- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Metabolism, Diabetes, and Cancer
- Intensive Care Unit Cognitive Disorders
- Molecular Biology Techniques and Applications
- Cardiac Arrest and Resuscitation
- Alcoholism and Thiamine Deficiency
- Mechanical Circulatory Support Devices
- Gene expression and cancer classification
- CRISPR and Genetic Engineering
- Acute Kidney Injury Research
Mayo Clinic
2020-2021
Lincoln Memorial University
2020
University of Virginia
2020
University School
2017
Case Western Reserve University
2017
Western University of Health Sciences
2017
Aims The aim of this study was to determine the diagnostic accuracy α defensin (AD) lateral flow assay (LFA) and enzyme-linked immunosorbent (ELISA) tests for periprosthetic joint infection (PJI) in comparison conventional synovial white blood cell (WBC) count polymorphonuclear neutrophil percentage (PMN%) analysis. Methods Patients undergoing aspiration evaluation pain after total knee arthroplasty (TKA) or hip (THA) were considered inclusion. Synovial fluids from 99 patients (25 THA 74...
There is interest in novel synovial fluid biomarkers for the detection of periprosthetic joint infection (PJI). Here, we assessed diagnostic accuracy 23 simple or sophisticated hip knee detection. One hundred seven subjects were studied, 57 whom had aseptic failure (AF) and 50 PJI. The following tested using spectrophotometric assays, immunoassays, lateral flow tests, test strips: leukocyte count, monocyte percentage, lymphocyte neutrophil C-reactive protein (CRP), glucose, lactate,...
The mechanism through which diet‐induced ketosis confers neuroprotection remains unknown. Studies have implicated in modulating cell‐signaling pathways. aims of this study was to investigate the effects on (i) recovery following transient focal cerebral ischemia (middle artery occlusion; MCAO) and (ii) signaling regulators cell growth‐survival corroborate these with circulating brain tissue metabolites. Methods Mice were fed a ketogenic diet (KG; 89.5% kcal fat) or standard chow (STD; 27.5%...
Numerous gene expression studies report the relative quantitation of by quantitative polymerase chain reaction (qPCR) compared to a control sample and reference gene. Although this method is suitable for animal in one tissue, humans severely limited absence or normalizing due variations related gender, race, ethnicity dietary preferences. Furthermore, between different tissues impossible gauge inherent differences levels expression. Absolute number mRNA molecule overcomes limitations not...