Wei Chen

ORCID: 0000-0003-1466-824X
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Mast cells and histamine
  • Cardiac Imaging and Diagnostics
  • Nutrition and Health in Aging
  • Cardiomyopathy and Myosin Studies
  • Mobile Health and mHealth Applications
  • Cardiac Fibrosis and Remodeling
  • Advanced MRI Techniques and Applications
  • Cardiac Structural Anomalies and Repair
  • Signaling Pathways in Disease
  • Cardiac pacing and defibrillation studies
  • Global Health Care Issues
  • Nutritional Studies and Diet
  • Heart Failure Treatment and Management
  • Liver Disease Diagnosis and Treatment
  • Cardiac Valve Diseases and Treatments
  • Renal cell carcinoma treatment
  • Frailty in Older Adults
  • Cell Adhesion Molecules Research
  • Digital Mental Health Interventions
  • Cardiac Arrhythmias and Treatments
  • Employment and Welfare Studies
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Atrial Fibrillation Management and Outcomes
  • Health Literacy and Information Accessibility

Peking Union Medical College Hospital
2016-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025

Hebei Medical University
2025

Third Hospital of Hebei Medical University
2025

Tokyo Medical and Dental University
2025

The First Affiliated Hospital, Sun Yat-sen University
2025

Sun Yat-sen University
2025

Stanford Health Care
2024

Capital Medical University
2012-2024

Beijing Friendship Hospital
2024

Abstract Background Identifying the temporal trends of kidney cancer (KC) incidence in both past and future at global national levels is critical for KC prevention. Methods We retrieved annual case data between 1990 2017 from Global Burden Disease (GBD) online database. The average percentage change (AAPC) was used to quantify age-standardized rates (ASRs) 2017. Bayesian age-period-cohort models were predict through 2030. Results Worldwide, number newly diagnosed cases increased 207.3...

10.1186/s40364-020-00195-3 article EN cc-by Biomarker Research 2020-05-13

Mouse models of myocardial infarction are essential tools for the study cardiac injury, repair, and remodeling. Our current investigation establishes a systematic approach quantitative evaluation inflammatory reparative response, function, geometry in mouse model reperfused infarction. Reperfused infarcts exhibited marked induction cytokines that peaked after 6 hr reperfusion. In infarcted heart, scar contraction chamber dilation continued at least 28 days reperfusion; infarct maturation was...

10.1369/0022155413493912 article EN Journal of Histochemistry & Cytochemistry 2013-05-28

China's mHealth market is on track to become a global leader by industry size. The Chinese mobile app and health care system have peculiarities that distinguish them from other markets. To date, apps not been systematically investigated.The objective of this study was provide an overview as December 2015.We identified investigated the most downloaded iOS Android platforms. For each app, we analyzed recorded its main service offered, initiative, disease specialty focus, cost, target user, Web...

10.2196/jmir.5955 article EN cc-by Journal of Medical Internet Research 2016-08-29

Abstract Mild photothermal therapy (PTT) has attracted attention for effectively avoiding the severe side effects associated with high‐temperature tumor ablation. However, its progress is hindered by limited availability of high‐performance agents (PTAs) and thermoresistance cancer cells induced heat shock reactions. Herein, this work proposes a new strategy to expand library organic small‐molecule PTAs utilize it construct multifunctional nano‐theranostic platform. By incorporating...

10.1002/adhm.202400766 article EN Advanced Healthcare Materials 2024-07-15

Abstract 31 P magnetic resonance spectroscopy was used to investigate changes in high energy phosphate levels and creatine kinase (CK) kinetics induced the human visual cortex during photic stimulation. CK evaluated by measuring apparent unidirectional rate constant ( k f ) “forward” direction (i.e., of ATP synthesis from phosphocreatine). increased 34% areas stimulation without significant steady‐state concentration compounds, indicating that turnover is elevated neuronal activity.

10.1002/mrm.1910380408 article EN Magnetic Resonance in Medicine 1997-10-01

The objective of this study was to assess nutritional risk and status Chinese hospitalized patients at admission discharge relations with clinical outcomes.A prospective, nationwide, multicenter conducted from June September 2014 in 34 large hospitals 18 cities China. Patients ≥ years a hospital stay 7-30 days were recruited. Anthropometric laboratory indicators, screening, assessment by Nutritional Risk Screening 2002 (NRS 2002) subjective global (SGA) performed within 24 hours discharge....

10.1080/07315724.2017.1304293 article EN Journal of the American College of Nutrition 2017-05-26

Abstract Background Despite the World Health Organization's prioritization of familial hypercholesterolemia (FH), its global diagnostic rate remains critically low, leading to inadequate treatment and control, thereby increasing risk atherosclerotic cardiovascular disease. This study aimed investigate comorbidity burden FH in China analyze differences between general (HC) populations. Methods Using a national medical insurance database from 2013 2017 including 13,976 patients with matched...

10.1002/nep3.72 article EN cc-by-nc-nd Neuroprotection/Neuroprotection (Chichester, England. Print) 2025-02-12

Abstract Background Chronic pain following calcaneal fracture surgery substantially diminishes patients' quality of life, yet effective risk prediction tools remain scarce. This study aimed to develop and validate a reliable predictive model for assessing the chronic development after surgery. Methods retrospective analysis examined 398 patients who underwent between January 2022 July 2023. Patients were randomly allocated into ( n = 280) validation 118) cohorts. Independent factors...

10.1186/s12891-025-08428-y article EN cc-by BMC Musculoskeletal Disorders 2025-02-19

Background: Long-term blood pressure variability (BPV) reflects fluctuations in BP over time, which may indicate instability precise control. We conducted a post hoc analysis of the data from SPRINT (Systolic Blood Pressure Intervention Trial) to assess effect and associated variables BPV on renal prognosis patients with hypertension. Methods: Excluding CKD, systolic (SBP) at 1st, 6th, 12th follow-up months were employed calculate SBP coefficient variation (CV) represented BPV. Patients...

10.7150/ijms.111843 article EN cc-by-nc International Journal of Medical Sciences 2025-04-22

To identify clinical incidence, risk factors and treatment of peripherally inserted central venous catheters (PICCs)-related upper extremity thrombosis (UEVT) in breast cancer patients undergoing chemotherapy.We performed a retrospective cohort study with PICC insertion chemotherapy. PICC-related UEVT was diagnosed by ultrasound. Patient-, catheter- insertion-related were analyzed univariable multivariable logistic regression to significant independent for UEVT. The incidence also analyzed.A...

10.5301/jva.5000457 article EN The Journal of Vascular Access 2015-04-09

Phase angle (PhA), a bioimpedance parameter, is used to assess the nutrition status and body composition of patients. Patients with pancreatic head cancer often present changes that relate adverse outcomes. PhA may be useful evaluate prognosis in these patients, but data are deficient. We aim explore effects on evaluation short-term outcome prediction This prospective study included 49 participants who underwent pancreaticoduodenectomy (PD). All participants’ nutritional postoperative...

10.3390/ijerph19116426 article EN International Journal of Environmental Research and Public Health 2022-05-25

Importance Parenteral enoxaparin is a preferred anticoagulant used in the acute phase for patients with coronary syndrome (ACS). The safety and efficacy of short-term low-dose rivaroxaban this clinical setting remain unknown. Objective To compare vs ACS. Design, Setting, Participants This multicenter, prospective, open-label, active-controlled, equivalence noninferiority trial was conducted from January 2017 through May 2021 6-month follow-up at 21 hospitals China. included ACS missing...

10.1001/jamanetworkopen.2022.55709 article EN cc-by-nc-nd JAMA Network Open 2023-02-10

This study examined whether alterations in myocardial creatine kinase (CK) kinetics and high-energy phosphate (HEP) levels occur postinfarction left ventricular remodeling (LVR). Myocardial HEP CK were 19 pigs 6 wk after infarction was produced by circumflex coronary artery ligation, the results compared with those from 9 normal pigs. Blood flow (microspheres), oxygen consumption (MV˙o 2 ), [ 31 P magnetic resonance spectroscopy (MRS)], ( MRS) measured myocardium remote infarct under basal...

10.1152/ajpheart.1999.276.3.h892 article EN AJP Heart and Circulatory Physiology 1999-03-01
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