A5011316150- Palliative Care and End-of-Life Issues
- Family and Patient Care in Intensive Care Units
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Grief, Bereavement, and Mental Health
- Complementary and Alternative Medicine Studies
- Yersinia bacterium, plague, ectoparasites research
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Patient Dignity and Privacy
- Ethics in medical practice
- Healthcare Decision-Making and Restraints
- Phytochemistry Medicinal Plant Applications
- Geriatric Care and Nursing Homes
- Patient-Provider Communication in Healthcare
- Childhood Cancer Survivors' Quality of Life
- Ginkgo biloba and Cashew Applications
- Healthcare professionals’ stress and burnout
- Renal Diseases and Glomerulopathies
- Forensic Entomology and Diptera Studies
- Cultural Competency in Health Care
- Innovations in Medical Education
- Healthcare Policy and Management
- Down syndrome and intellectual disability research
- Airway Management and Intubation Techniques
New York Hospital Queens
2014-2024
Cornell University
2015-2024
Weill Cornell Medicine
2019-2024
Regeneron (United States)
2020-2024
Columbia University Irving Medical Center
2024
Presbyterian Hospital
2015-2024
Lower Manhattan Hospital
2024
Texas Health Dallas
2022-2024
Allen Hospital
2024
Thomas Jefferson University
2023
BackgroundRecent data suggest that complications and death from coronavirus disease 2019 (Covid-19) may be related to high viral loads.MethodsIn this ongoing, double-blind, phase 1–3 trial involving nonhospitalized patients with Covid-19, we investigated two fully human, neutralizing monoclonal antibodies against severe acute respiratory syndrome 2 (SARS-CoV-2) spike protein, used in a combined cocktail (REGN-COV2) reduce the risk of emergence treatment-resistant mutant virus. Patients were...
In the phase 1-2 portion of an adaptive trial, REGEN-COV, a combination monoclonal antibodies casirivimab and imdevimab, reduced viral load number medical visits in patients with coronavirus disease 2019 (Covid-19). REGEN-COV has activity vitro against current severe acute respiratory syndrome 2 (SARS-CoV-2) variants concern. 3 we randomly assigned outpatients Covid-19 risk factors for to receive various doses intravenous or placebo. Patients were followed through day 29. A prespecified...
Background. Older adults are increasingly using complementary and alternative medicine (CAM) dietary supplements herbal remedies, but may not discuss this with their physicians. When patients do report CAM, physicians record information in patient charts.
Abstract Background The open-label RECOVERY study reported improved survival in hospitalized, SARS-CoV-2 seronegative patients treated with casirivimab and imdevimab (CAS + IMD). Methods In this phase 1/2/3, double-blind, placebo-controlled trial conducted prior to widespread circulation of Delta Omicron, hospitalized COVID-19 were randomized (1:1:1) 2.4 g or 8.0 CAS IMD placebo, characterized at baseline for viral load serostatus. Results total, 1336 on low-flow no supplemental...
Objective: To investigate the prevalence and predictors of use complementary alternative medicine (CAM) by elderly. Design: Cross-sectional survey examining patterns therapies in two urban multiethnic populations older adults. Setting Subjects: A convenience sample 421 participants were interviewed at sites: a university geriatrics primary care practice veterans medical clinic, both New York City. Subjects excluded if they did not speak English or moderately cognitively impaired....
ABSTRACT Background REGEN-COV antibody cocktail (casirivimab with imdevimab) rapidly reduced viral load and decreased medically-attended visits in the phase 1/2 portion of this trial; REGEN-COV, retains activity vitro against emerging SARS-CoV-2 variants concern. Methods The 3 adaptive, randomized, master protocol, included 4,057 Covid-19 outpatients one or more risk factors for severe disease. Patients were randomized to a single treatment intravenous placebo, various doses followed 28...
In the United States, majority of deaths occur in hospital but dying process there is at best unsatisfactory and more likely inadequate for both patients caregivers. The development hospital-based palliative care programs (HBPCPs) can vastly improve inpatient end-of-life care. This study first to examine prevalence characteristics HBPCPs thus providing a snapshot these HBPCPs. It also serves as baseline benchmark against which future patterns be compared. Phase 1: Data were obtained from...
Futile or potentially inappropriate care (futile/PIC) has been suggested as a factor contributing to clinician well-being; however, little is known about this association.To determine whether futile/PIC provision associated with measures of well-being.Cross-sectional, self-administered, online questionnaire.Two New York City Hospitals.Attending physicians, residents, nurses, and physician assistants in the fields internal medicine, surgery, neurology, intensive care.Provision perceived...
Background: Futile or potentially inappropriate care (futile/PIC) for dying inpatients leads to negative outcomes patients and clinicians. In the setting of rising end-of-life health costs increasing physician burnout, it is important understand causes futile/PIC, how impacts on relates burnout. Objectives: Examine determine whether clinicians report compensatory avoidant behaviors as a result such assess these are associated with Design: Online, cross-sectional questionnaire....
Context: The COVID-19 pandemic resulted in a surge of critically ill patients that strained health care systems throughout New York City March and April 2020. At the peak crisis, consults for palliative increased four- to sevenfold at NewYork-Presbyterian (NYP), an academic system with 10 campuses City. We share our challenges, solutions, lessons learned help peer institutions meet demands during future crises address pre-existing subspecialist shortages nonpandemic times.
A paucity of literature describes the growing Chinese American community's end-of-life (EOL) priorities and preferences.Develop a culturally-tailored advance care planning (ACP) tool to understand EOL preferences this underserved minority group.Informed by Cultural Appropriateness Theory, Coalition for Compassionate Care (CACCC) developed Heart (HTH) Cards using 3-step approach. First, CACCC created refined list bilingual, culturally relevant issues. Next, organized issues into card deck....
<h3>Importance</h3> The monoclonal antibody combination of casirivimab and imdevimab reduced viral load, hospitalization, or death when administered as a 1200-mg greater intravenous (IV) dose in phase 3 COVID-19 outpatient study. Subcutaneous (SC) and/or lower IV doses should increase accessibility drug supplies for patients. <h3>Objective</h3> To assess the virologic efficacy across different SC compared with placebo. <h3>Design, Setting, Participants</h3> This 2, randomized, double-blind,...
ABSTRACT Background Continued SARS-CoV-2 infections and COVID-19-related hospitalizations highlight the need for effective anti-viral treatments in outpatient setting. In a descriptive interim analysis of phase 1/2 portion double-blind 1/2/3 trial COVID-19 outpatients conducted between June 16, 2020 September 4, 2020, REGEN-COV ® (casirivimab plus imdevimab) antibody combination reduced viral load versus placebo. Methods This final comprises 799 outpatients, including 275 from previous...
Background: Burnout during residency may be a function of intense professional demands and poor work/life balance. With the onset COVID-19 pandemic, NYC hospital systems were quickly overwhelmed, trainees required to perform beyond usual clinical duties with less supervision limited education. Objective: The present longitudinal study examined effects caseload over time on burnout experienced by resident physicians explored demographic characteristics organizational personal factors as...
Strategies to reduce the documented disparities in health and care for rapidly growing numbers of older patients from diverse ethnic populations include increased cultural competence providers. To assist geriatric faculty medical other professional schools develop training their ethnogeriatric programs, University California Academic Geriatric Resource Program partnered with Ethnogeriatric Committee American Geriatrics Society a curricular framework. The framework includes core competencies...
<b><i>Background:</i></b> Postoperative delirium in the elderly is a growing concern. Data regarding significant differences postoperative cognitive dysfunction (POCD) persons undergoing laparoscopic versus open colon resection are not well established. <b><i>Objectives:</i></b> The goal of this study was to compare incidence POCD surgery an population. <b><i>Design and Setting:</i></b> A prospective nonrandomized pilot...
Abstract Objective The objectives of this study were to develop and refine EMPOWER (Enhancing Mobilizing the POtential for Wellness Resilience), a brief manualized cognitive-behavioral, acceptance-based intervention surrogate decision-makers critically ill patients evaluate its preliminary feasibility, acceptability, promise in improving surrogates’ mental health patient outcomes. Method Part 1 involved obtaining qualitative stakeholder feedback from 5 bereaved surrogates 10 critical care...
BACKGROUND: Race and ethnicity are important predictors of health care access outcomes, but quality their documentation in the healthcare system is often problematic. OBJECTIVES: To study agreement between Medicare Medicaid descriptions race older beneficiaries. DESIGN: Quasiexperimental design a natural practice setting. SETTING: New Jersey. PARTICIPANTS: 153,241 dually enrolled participants Medicaid. MEASUREMENTS: Agreement rates administrative databases on recipients' ethnicity. RESULTS:...
Objectives: To assess the status of geriatric medicine (GM) fellows' training experiences in end‐of‐life care via self‐report. Design: Anonymous surveys completed by mail, Web access, and telephone. Setting: U.S. accredited GM fellowship programs. Participants: Two hundred ninety‐six were sent to graduating fellows 1‐ 2‐year programs across Unites States. Measurements: Measurements assessed self‐reported attitudes, quantity quality education, preparation provide care, perceived value caring...