- Bone Tissue Engineering Materials
- Dental materials and restorations
- Endodontics and Root Canal Treatments
- Silk-based biomaterials and applications
- Graphene and Nanomaterials Applications
- Salivary Gland Disorders and Functions
- Dental Erosion and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Thyroid Disorders and Treatments
- biodegradable polymer synthesis and properties
- Biochemical Analysis and Sensing Techniques
- Additive Manufacturing and 3D Printing Technologies
- Reconstructive Surgery and Microvascular Techniques
- Nanoparticle-Based Drug Delivery
- Wound Healing and Treatments
- Dental Anxiety and Anesthesia Techniques
- Craniofacial Disorders and Treatments
- Orthopaedic implants and arthroplasty
- Cleft Lip and Palate Research
- Tissue Engineering and Regenerative Medicine
- Orthodontics and Dentofacial Orthopedics
- Surgical Sutures and Adhesives
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Connective tissue disorders research
Beihang University
2023-2024
Ministry of Industry and Information Technology
2024
Jilin University
2018-2022
Jilin Medical University
2021
Donghua University
2020
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials
2020
Effective bone defect repair has been a tough clinical challenge due to the complexity of microenvironment. Hydrogels loaded with marrow mesenchymal stem cells (BMSCs) have widely applied for regeneration. However, low survival BMSCs at site transplantation and lack sufficient osteogenic induction capacity greatly limit their applications. In order solve this puzzle, we fabricated gelatin methacryloyl (GelMA) hydrogels containing cerium oxide (CeO
Commercial dentin adhesive systems are applied to restorations due their resistant bonding properties, but they suffer from the lack of bioactivity and prone hydrolysis. Therefore, overcome these limitations, an eco-friendly natural monomer, urushiol, was adopted be a primer in its interaction with collagen antibacterial activity, preventing further hydrolysis development. First, urushiol determined capable improving biological stability through cross-linking. Using high-fidelity analytical...
The dentin collagen matrix that is not completely enveloped by resin adhesive vulnerable to degradation intrinsic collagenases during the etch-and-rinse process, which contributes deterioration of bonding interface. Current commercial adhesives have no functional components can form covalent bonds matrix. In this study, a photocurable aldehyde, 4-formylphenyl acrylate (FA), was synthesized and for first time applied as primer in dentistry covalently bind collagen. Experimental groups with...
Hydrolysis resistance is essential to the durability of dentin bonding interface. Urushiol a natural monomer that has been used in different fields over thousands years but disadvantage long drying time. In this study, we evaluated novel photocurable derivative urushiol as main for polymerization adhesive and its effect on hydrolysis resistance. The was characterized by Fourier transform infrared spectroscopy 1H nuclear magnetic resonance spectroscopy. Compared with Adper Single Bond 2,...
In this study, we evaluated a novel functional monomer (4-formylphenyl acrylate [FA]) that can specifically and covalently bind to the dentin collagen matrix as potential alternative hydrophobic diluent-like for improving durability of bonding. Experimental adhesives with different FA contents (0%, 10%, 20%, 30%) were partial substituents hydrophilic 2-hydroxyethyl methacrylate, commercial adhesive One-Step (Bisco, Inc.) employed positive control. Their degree conversion, viscosity,...
Bonding failure is one of the main causes dental restorations.
Objective: This study aims to synthesize a new biodegradable and biomineralized guided bone regeneration membrane. Experimental Methods: Poly(propylene carbonate) (PPC) nanohydroxyapatite (nHAp) were prepared by solvent casting/particulate leaching made into membranes with different compositions (0%,10%,20%, 30%, 40% nHAp/PPC). Their mechanical properties, cell compatibilities fibroblast barrier functions studied in vitro. Results: Scanning electron microscopy showed that the nHAp/PPC...
This study aims to evaluate the ability of poly(propylene carbonate) (PPC)-loaded nanohydroxyapatite (nHAp) membrane regenerate bones. Methods: Six New Zealand white rabbits were randomly and equally divided into two groups. Four 6 mm diameter transosseous round defects made at parietal bone each rabbit. One defect was not covered with membrane, others 10% or 20% nHAp/PPC HEAL-ALL membrane. Animals group sacrificed 4 12 weeks after operation, respectively. The rabbit bones removed for...
Surgery-first for a patient with mild hemifacial microsomia: A case report and review of literature