A5104668804- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Disease and Adiposity
- Reproductive Biology and Fertility
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Ovarian function and disorders
- Sirtuins and Resveratrol in Medicine
- Cancer Cells and Metastasis
- Neurotransmitter Receptor Influence on Behavior
- Bone and Dental Protein Studies
- Biomarkers in Disease Mechanisms
- Injury Epidemiology and Prevention
- Exercise and Physiological Responses
- IgG4-Related and Inflammatory Diseases
- Pulmonary Hypertension Research and Treatments
- Antioxidant Activity and Oxidative Stress
- Cancer, Hypoxia, and Metabolism
- Ferroptosis and cancer prognosis
- Cardiovascular Function and Risk Factors
- Soft tissue tumor case studies
- Respiratory Support and Mechanisms
- Neuropeptides and Animal Physiology
- Oral and Maxillofacial Pathology
- Pain Mechanisms and Treatments
- Thyroid Cancer Diagnosis and Treatment
Xuzhou Medical College
2017-2024
Yangzhou University
2018-2020
Institute of Zoology
2015-2017
Chinese Academy of Sciences
2015-2017
University of Chinese Academy of Sciences
2015-2017
Tongji Hospital
2010
Huazhong University of Science and Technology
2010
Increasing evidence indicates that brown adipose tissue (BAT) transplantation enhances whole-body energy metabolism in a mouse model of diet-induced obesity. However, it remains unclear whether BAT also has such beneficial effects on genetically obese mice. To address this issue, we transplanted from C57/BL6 mice into the dorsal subcutaneous region age- and sex-matched leptin deficient Ob/Ob Interestingly, led to significant reduction body weight gain with increased oxygen consumption...
Significance In the current study, we show that brown adipose tissue (BAT) activity is dramatically reduced in a dehydroepiandrosterone (DHEA)-induced polycystic ovary syndrome (PCOS) rat when compared with normal control rat. Importantly, key features of PCOS (such as insulin resistance and irregular estrous cycle) are alleviated after BAT transplantation. Mechanistically, transplanted enhances endogenous thereby increases circulating adiponectin level, which was lower both patient model....
Increasing energy expenditure through activation of brown adipose tissue (BAT) is a critical approach to treating obesity and diabetes. In this study, rutin, natural compound extracted from mulberry drug used as capillary stabilizer clinically for many years without any side effects, regulated whole-body metabolism by enhancing BAT activity. Rutin treatment significantly reduced adiposity, increased expenditure, improved glucose homeostasis in both genetically obese (Db/Db) diet-induced...
Osteopontin (OPN), a member of the small integrin binding ligand N-linked glycoprotein family, has been analyzed in numerous types human malignancy.The present study detected expression levels OPN and evaluated its role tumor progression patients with non-small cell lung cancer (NSCLC).OPN were using immunohistochemistry 101 NSCLC tumors. The mRNA protein have significant difference between advanced stage I/II NSCLC. drug resistance, invasive ability lactate production lines (A549 SK-MES-1)...
In brief Brown adipose tissue impaired in polycystic ovary syndrome (PCOS) plays a crucial role the treatment of PCOS. This study shows that myricetin potently improves PCOS by activating brown (BAT). Abstract is complex endocrine disease characterized hyperandrogenism, anovulation and ovary, often accompanied metabolic disorder such as insulin resistance. BAT has been considered promising target for obesity other disease. this study, we showed 3 weeks (a compound from natural product)...
Drag-reducing polymers (DRPs) was previously demonstrated to increase blood flow, tissue perfusion, and reduce vascular resistance. The purpose of this study investigate the effect DRPs on pulmonary remodeling right ventricular dysfunction in a rat model chronic hypoxia-in duced hypertension (HPH). A total forty male Wistar rats were randomly equally assigned into four experimental groups (Group I: normoxia + saline, Group II: PEO, III: hypoxia IV: PEO) maintained (21% O2) or hypobaric (10%...