Tian Tian

ORCID: 0000-0003-1485-8449
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About
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Research Areas
  • Smart Grid and Power Systems
  • Power Transformer Diagnostics and Insulation
  • High-Voltage Power Transmission Systems
  • Power Systems and Technologies
  • Advancements in PLL and VCO Technologies
  • Electromagnetic Compatibility and Noise Suppression
  • Radio Frequency Integrated Circuit Design
  • High voltage insulation and dielectric phenomena
  • Electric Vehicles and Infrastructure
  • Microbial Natural Products and Biosynthesis
  • Power Systems and Renewable Energy
  • Animal Ecology and Behavior Studies
  • Advanced Sensor and Control Systems
  • Microwave Engineering and Waveguides
  • Granular flow and fluidized beds
  • Smart Grid Energy Management
  • Electric Motor Design and Analysis
  • Wildlife Ecology and Conservation
  • Advanced Wireless Communication Techniques
  • Hybrid Renewable Energy Systems
  • Advanced Computational Techniques and Applications
  • Underwater Acoustics Research
  • Advanced Battery Technologies Research
  • Electric and Hybrid Vehicle Technologies
  • Non-Destructive Testing Techniques

China University of Geosciences
2025

Guangzhou Institute of Energy Conversion
2021-2024

Chinese Academy of Sciences
2010-2024

Fudan University
2024

University of California, Davis
2024

University of Chinese Academy of Sciences
2007-2024

Institute of Information Engineering
2023-2024

Institute of Zoology
2023

Center for Excellence in Molecular Plant Sciences
2022

Ningxia Water Conservancy
2020-2022

In this work, we have developed multiple-armed DNA tetrahedral nanostructures (TDNs) for dual-modality in vivo imaging using near-infrared (NIR) fluorescence and single-photon emission computed tomography (SPECT). We found that the presence of arm strands TDNs remarkably enhanced their vitro stability, allowing them to stay intact at least 12 h serum. By NIR imaging, evaluated mice pharmacokinetics TDNs, which exhibited distinctly different biodistribution patterns compared with those...

10.1021/acsami.5b10792 article EN ACS Applied Materials & Interfaces 2016-01-27

The gingival epithelium-capillary interface is a unique feature of periodontal soft tissue, preserving tissue homeostasis and preventing microorganism toxic substances from entering the subepithelial tissue. However, function disturbed in periodontitis, mechanisms breakdown are incompletely understood. To address these limitations, we developed microfluidic barrier with thin culture membrane (10 μm) that closely mimics vivo epithelial an immune micro-environment. test validity fabricated...

10.3390/bios12050345 article EN cc-by Biosensors 2022-05-18

40 Hz light flicker is a well-known non-invasive treatment that thought to be effective in treating Alzheimer's disease. However, the effects of visual stimulation on neural networks, synaptic plasticity, and learning memory wild-type animals remain unclear.We aimed explore impact place cell, mice.c-Fos+ cell distribution vivo electrophysiology was used chronic networks neuroplasticity mice. The character c-Fos+ brain changes corticosterone levels blood were investigate state animal. Place...

10.3233/jad-215212 article EN Journal of Alzheimer s Disease 2021-10-02

Cocaine, the archetypal tropane alkaloid from plant genus Erythroxylum, has recently been used clinically as a topical anesthesia of mucous membranes. Despite this, key biosynthetic step requisite skeleton (methylecgonone) identified intermediate 4-(1-methyl-2-pyrrolidinyl)-3-oxobutanoic acid (MPOA) remained, until this point, unknown. Herein, we identify two missing enzymes (EnCYP81AN15 and EnMT4) necessary for biosynthesis in cocaine by transient expression candidate genes Nicotiana...

10.1021/jacs.2c09091 article EN Journal of the American Chemical Society 2022-11-14

Abstract Tropane alkaloids such as hyoscyamine and cocaine are of importance in medicinal uses. Only recently has the biosynthetic machinery become complete. However, biosynthesis pathway remains only partially elucidated. Here we characterize polyketide synthases required for generating 3-oxo-glutaric acid from malonyl-CoA route. Structural analysis shows that these two adopt distinctly different active site architecture to catalyze same reaction pyrrolidine ketide synthase biosynthesis,...

10.1038/s41467-022-32776-1 article EN cc-by Nature Communications 2022-08-25

Montane small mammals are subjected to strong forces of dispersal limitation and habitat filtering that mainly operate on their community structures along the altitudinal direction. However, so far little is known about relative contributions niche processes assembly. By applying newly proposed PER‐SIMPER/DNCI (dispersal–niche continuum index) framework mammal occurrence data collected from 21 extensive gradients, we quantitatively assessed importance mammalian assembly in a large...

10.1111/ecog.06318 article EN cc-by Ecography 2022-06-23

An electronic current transformer with a B-dot sensor is proposed in this study. The can realize the measurement of transmission line non-contact way accordance principle magnetic field coupling. multiple electrodes series-opposing structure applied together differential input structures and active integrating circuits, which allow to operate mode. Maxwell software adopted model simulate sensor. Optimization structural parameters conducted through finite-element simulation. A test platform...

10.3390/s17040820 article EN cc-by Sensors 2017-04-10

When the transformer is running, vibration which generated in core and winding will spread outward through medium of metal, oil, air. The magnetic field changes with variation excitation source state core, so corresponding noise change. Therefore, contain a lot information. If information can be associated fault characteristics transformer, it significant to evaluate running signal, improve intelligence, safety, stability operation. Based on this, modeling simulation multi-point grounding,...

10.3389/fenrg.2023.1169508 article EN cc-by Frontiers in Energy Research 2023-04-27

A 61-kb biosynthetic gene cluster (BGC), which is accountable for the biosynthesis of hibarimicin (HBM) B from Microbispora rosea subsp. hibaria TP-A0121, was heterologously expressed in Streptomyces coelicolor M1154, generated a trace target products but accumulated large amount shunt products. Based on rational analysis relevant secondary metabolism, directed engineering pathways resulted high production HBM B, as well new derivates with improved antitumor activity. These results not only...

10.1016/j.eng.2024.01.012 article EN cc-by-nc-nd Engineering 2024-02-10

Embedded Dynamic RAM (eDRAM) has become a key solution for large-capacity cache in high-performance processors. A heterogeneous two transistor capacitorless eDRAM (2T-eDRAM) that combines silicon and molybdenum disulfide (MoS

10.1038/s41467-024-54218-w article EN cc-by-nc-nd Nature Communications 2024-11-12

To investigate the spatial synergy between agricultural development level and transport superiority degree in grain-producing areas of central Jilin Province driving mechanism them, 22 counties were used as research units to calculate using entropy weighting method, weighted travel time raster cost distance. The econometric model was analyze mutual influence two. main conclusions are follows. 1) Agricultural around Changchun, provincial capital city, Changchun-Jilin Changchun-Gongzhuling is...

10.1007/s11769-022-1291-3 article EN Chinese Geographical Science 2022-07-14

We propose a new highly reliable and lightweight embedded optical torque sensor for biomimetic robot arm enabling the measurement in joints, which can measure of joint by detecting torsion its elastic element (mechanical structure or flexure element). Flexure spring is introduced as this paper. Because curve modeling, not inclined to be broken contrast crossbeam structure, commonly used sensor. Thanks we build an extremely compact size. Six types are proposed paper, have potential...

10.1155/2018/4362749 article EN cc-by Applied Bionics and Biomechanics 2018-01-01

Dissolved gas analysis (DGA) is a common technology used in the on-site maintenance of oil-immersed power transformers industry at present. However, when content dissolved oil reaches attention value DGA method can effectively diagnose operating state transformer. Due to lack production data free which was detected faults occur, cannot timely transformer status. To solve above problem, an experimental platform built for studying generation law under discharge faults, and characteristic...

10.3389/fenrg.2022.1056604 article EN cc-by Frontiers in Energy Research 2023-01-17

Magnetic lead screw (MLS) owns many merits for wave energy generation system applications. However, to resist the huge, instantaneous impact of waves, radius mover and rotor MLS should be large obtain sufficient stiffness. And length needs match height transfer as much power possible. Therefore, a great permanent magnets (PMs) will consumed when size traditional is maximum thrust force would greater than excitation force. This waste PMs poor starting performance. Also, ideal spiral are quite...

10.1109/iecon43393.2020.9255013 article EN IECON 2020 The 46th Annual Conference of the IEEE Industrial Electronics Society 2020-10-18

Abstract In this work the influences of solid viscosity and way to scale-down traditional drag models on predicted hydrodynamics Geldart A particles in a lab-scale gas-solid bubbling fluidized bed are investigated. To evaluate effects models, modified Gibilaro et al. model (constant correction factor) EMMS (non-constant tested. And assessed by considering empirical proposed Gidaspow (1997, Turbulence, Viscosity Numerical Simulation FCC Particles CFB. Fluidization Fluid-particle Systems,...

10.1515/ijcre-2017-0016 article EN International Journal of Chemical Reactor Engineering 2017-11-17

This article presents a novel self-biased phase-locked loop (PLL) scheme for wireless local area network (WLAN) applications. A circuit that contains current mirror and variable resistor related to the frequency division ratio are proposed. The proposed PLL achieves fixed damping factor. Moreover, technology allows bandwidth track input reference ratio. start-up speeds up locking of PLL. In addition, differential-to-single-ended (DTS) converter can guarantee 50% duty cycle without operating...

10.3390/electronics10172077 article EN Electronics 2021-08-27

As the increasing application of ICT technology in power system, information available is getting more and more, which has provided a firm foundation possibility to implementation Active Distribution System (ADS). The key challenges at ADS planning how integration with optimization operation DER (generation (DG, RES), Electricity Energy storage (EES) interactive load). questions firstly make use information,secondly primary needed have be , thirdly coordinate resources. This paper presents...

10.1049/cp.2013.0801 article EN 22nd International Conference and Exhibition on Electricity Distribution (CIRED 2013) 2013-01-01

This paper presents a study of the influences DBC metal trace layout on reliability high power IGBT module. The research is conducted seven-layer package model using finite element analysis simulation. A parametric carried out at different temperatures to simulate thermal-cycling scenario. It shows in simulation that both total deformation and thermal stress are not balanced even symmetrical edges related area DBC, larger results higher stress. Thermal-cycling experiment verify certain...

10.1109/wipda.2015.7369299 article EN 2015-11-01
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