A5084810244- Advanced Glycation End Products research
- Dye analysis and toxicity
- Edible Oils Quality and Analysis
- Tea Polyphenols and Effects
- Phytochemicals and Antioxidant Activities
- Congenital Diaphragmatic Hernia Studies
- Potato Plant Research
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Neurofibromatosis and Schwannoma Cases
- COVID-19 Impact on Reproduction
- Congenital Anomalies and Fetal Surgery
- Streptococcal Infections and Treatments
- Urinary Tract Infections Management
- Blood disorders and treatments
- Electrolyte and hormonal disorders
- Food Quality and Safety Studies
- Antibiotic Use and Resistance
- Chromatin Remodeling and Cancer
- Immunodeficiency and Autoimmune Disorders
- Neuroendocrine Tumor Research Advances
- Potassium and Related Disorders
- Adenosine and Purinergic Signaling
- Neonatal and Maternal Infections
University of Genoa
2024
Istituto Giannina Gaslini
2021-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2024
Abstract COVID-19 has a mild clinical course with low mortality rate in general pediatric population, while variable outcomes have been described children cancer. Infectious diseases working party of the AIEOP collected data on characteristics and SARS-CoV-2 infections oncology/hematology patients from April 2020 to May 2021, including second third waves pandemic Italy. Factors potentially associated moderate, severe, or critical were analyzed. Of 153 SARS-Cov2 recorded, 100 asymptomatic 53...
Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive disease associated with a highly variable clinical presentation, such as vasculitis, inflammation, and hematologic manifestations. Some associations features can mimic autoimmune lymphoproliferative syndrome (ALPS). We report case female patient who fulfilled the 2009 National Institute Health revised criteria for ALPS received delayed diagnosis DADA2. During her childhood, she suffered from hemolytic anemia, immune...
The occurrence of an abdominal tumor invading the spinal canal and causing symptoms epidural compression is rare in infant, exceptional at birth. Peripheral neuroblastic tumors are by far most common cause. Emergency chemotherapy commonly curative, though permanent sequelae possible. Although other malignancies may be involved, no case rhabdoid birth has been reported. We describe a neonate who presented secondary to tumor. As expected with this highly malignant tumor, patient experienced...
Abstract Objective The objective of this study was to assess the clinical impact and outcome SARS-CoV-2 infection on children with cancer or those who received a hematopoietic stem cell transplantation. Methods AIEOP (Italian Association Pediatric Hematology Oncology) performed nationwide multicenter observational cohort study, including consecutive patients between April 2020 November 2022. Results Twenty-five Italian centers participated 455 were enrolled. We reported significant...
Abstract Background Cefiderocol is a siderophore cephalosporin active against Gram negative (GN) carbapenem resistant bacteria, approved in Italy September 2020 for adult patients. In pediatric population off label use allowed when severe infections from multidrug resistance (MDR) GN bacteria occur. Recently, some authors reported the emergence, among strains of Enterobacterales to ceftazidime avibactam, cross-resistance with cefiderocol. The aim this study describe increased Minimal...
Abstract Background Antimicrobial resistance (AMR) among Gram Negative (GN) bacteria is a medical and economic concern. In the pediatric setting there paucity AMR data due to lower surveillance in this population. Aim of study describe incidence outcomes GN bloodstream infections (GN-BSI), especially caused by MDR children admitted intensive care unit Istituto Giannina Gaslini Pediatric Hospital Genoa from January 2017 December 2021. Methods retrospective observational single-center all...