A5031819623- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Sports injuries and prevention
- Orthopedic Surgery and Rehabilitation
- Nerve Injury and Rehabilitation
- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Bone health and treatments
- Hip disorders and treatments
- Cardiac Valve Diseases and Treatments
- Elbow and Forearm Trauma Treatment
- Bone fractures and treatments
- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Cardiovascular Syncope and Autonomic Disorders
- Traumatic Brain Injury Research
- Prostate Cancer Treatment and Research
- Musculoskeletal pain and rehabilitation
- Venous Thromboembolism Diagnosis and Management
- Lower Extremity Biomechanics and Pathologies
- Virus-based gene therapy research
- Orthopedic Infections and Treatments
- Bone Metabolism and Diseases
- Surgical Sutures and Adhesives
- Orthopaedic implants and arthroplasty
University of Southern California
2016-2025
Keck Hospital of USC
2014-2024
Southern California University for Professional Studies
2020-2021
University of Utah
2017
Emory University
2017
University of California, Los Angeles
2001-2013
Cedars-Sinai Medical Center
2013
Coastline Community College
2013
Zimmer Biomet (United States)
2013
NewYork–Presbyterian Hospital
2011
Despite clinical success rates over 85%, persistent anatomic defects after rotator cuff repair are common and depend on the size of tear repaired. The etiology delayed or failed tendon to bone healing is multifactorial biologic augmentation a would be clinically desirable. Autogenous platelets contain many growth factors critical in physiology bone, soft tissue, wound healing. Growth present include TGF-B, FGF, PDGF, EGF, VEGF. Centrifugation techniques have been developed create platelet...
Background: Treatment of superior labral anterior posterior (SLAP) tears remains controversial, particularly in older age groups. Repair, debridement, biceps tenodesis, tenotomy, and observation have been recommended depending on patient characteristics, but there not any large epidemiologic studies investigating treatment trends. Purpose: To investigate current trends SLAP repair across time, gender, age, regions the United States. Study Design: Descriptive epidemiology study. Methods:...
Since its approval, reverse total shoulder arthroplasty (rTSA) has continued to increase in usage, with expanding indications beyond rotator cuff arthropathy. Existing literature captured further increased utilization over the last decade through 2017. However, this data not been updated include a contemporary cohort of patients. This study sought determine trends anatomic (aTSA), rTSA, and hemiarthroplasty (HA) usage based on primary diagnosis number surgeons performing each procedure...
Dendritic cells (DC) are potent stimulators of primary T cell responses. In this study, we demonstrate that DC, genetically engineered to express the MART-1/Melan-A (MART-1) tumor-associated Ag, MART-1 mRNA and protein, correctly process present HLA-A2.1-restricted immunodominant peptide (MART-1(27-35)), serve as MART-1-specific CTL in vitro. A replication-defective E1-deleted adenovirus (AdV) was constructed expresses (AdVMART1). Transduced DC produce full length well protein. AdVMART1 does...
We examined the potential of ex vivo gene therapy to enhance bone repair using lentiviral vectors encoding either enhanced green fluorescent protein (EGFP) as a reporter or morphogenetic protein-2 (BMP-2) downstream cytomegalovirus immediate early (CMV) promoter murine leukemia virus long terminal repeat (RhMLV) derived from retrovirus adapted replicate in rhesus macaque. In vitro, rat marrow stromal cells (BMSCs) transduced with Lenti-CMV-EGFP Lenti-RhMLV-EGFP demonstrated over 90%...
Few data are available to evaluate approach-related differences in perioperative complications with lumbar interbody fusion devices. Complications occurring the intraoperative and immediate postoperative period were identified categorized for 31 consecutive posterior fusions (PLIFs) 88 anterior (ALIFs). In this study, all conducted threaded cylindrical devices as stand-alone internal fixation Multivariate analysis was used account potential covariates identify factors associated an increased...
Abstract The purpose of this study was to evaluate the role BMPs on formation metastatic prostate cancer lesions bone. Our results show that influence development and progression osteoblastic suggest therapies inhibit BMP activity may reduce lesions. Introduction: Prostate adenocarcinoma is leading cause in North American men. skeletal metastases affects ∼70% patients with advanced disease, a majority these have Although been found be expressed multiple oncogenic cell lines, their remains...
Background Avulsion of the rectus femoris origin is a rare injury. The only previous report this injury in professional American football has been limited to kicking athlete. Purpose To describe incidence and treatment proximal avulsion National Football League (NFL). Study Design Case series; Level evidence, 4. Methods NFL Injury Surveillance System (NFLISS) was reviewed for any injuries from 1986 2006, including type mechanism injury, player demographics, method treatment, time return...
Prolonged systemic administration of corticosteroids causes osteoporosis and increased risk fracture. Despite this well documented side effect corticosteroids, the these compounds on fracture healing is not defined. The goal study was to test hypothesis that corticosteroid therapy adversely affects in a rabbit ulnar osteotomy model. Non-critical sized (1 mm) defects were created bilaterally 18 adult female New Zealand White rabbits. Starting 2 months before operative intervention continuing...
Background: Studies evaluating multilevel surgery to treat spastic deformity and functional deficits in cerebral palsy (CP) usually focus on data from instrumented gait analysis clinical examination without examining health-related quality of life (HRQOL) outcomes. Recently, outcome measures for well-being children with a variety musculoskeletal disorders have also been validated specifically CP. Therefore, this study aimed investigate the impact function HRQOL group ambulatory Methods: In...
Up to 1 billion people have insufficient or deficient vitamin D levels. Despite the well-documented, widespread prevalence of low levels and importance for athletes, there is a paucity research investigating deficiency in athletes.We investigated abnormal National Collegiate Athletic Association (NCAA) Division I college athletes at single institution. We hypothesized that insufficiency prevalent among our cohort.Cohort study.Level 1.We measured serum 25-hydroxyvitamin (25(OH)D) 223 NCAA...
Anterior cruciate ligament (ACL) injury is prevalent among National Collegiate Athletic Association (NCAA) soccer players. Controversy remains regarding the effect of surface type on rate ACL in players, considering differences sex, athletic exposure, and level competition.Natural grass surfaces would be associated with decreased NCAA Sex, exposure (match vs practice), competition (Division I-III) affect relationship between playing rates.Cohort study; Level evidence, 3.Using Injury...
Although single injections with anesthetics are commonly administered given their safety, short-acting nature limits pain control. Liposomal bupivacaine represents a promising alternative to plain in interscalene nerve blocks. The goal of our study was determine whether an block liposomal provides superior analgesia and reduces opioid requirements compared patients undergoing arthroscopic rotator cuff repair (ARCR). A single-center, double-blinded, randomized controlled trial ARCR performed....