Muhammad Faraz Khan

ORCID: 0000-0003-1525-003X
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • COVID-19 Clinical Research Studies
  • COVID-19 epidemiological studies
  • Ethnobotanical and Medicinal Plants Studies
  • Antibiotic Resistance in Bacteria
  • Natural Antidiabetic Agents Studies
  • COVID-19 diagnosis using AI
  • Bacterial biofilms and quorum sensing
  • COVID-19 and healthcare impacts
  • Complementary and Alternative Medicine Studies
  • Epigenetics and DNA Methylation
  • Differential Equations and Numerical Methods
  • Nanoparticles: synthesis and applications
  • Antimicrobial Peptides and Activities
  • Sesquiterpenes and Asteraceae Studies
  • Phytochemistry and Biological Activities
  • Thermoregulation and physiological responses
  • Long-Term Effects of COVID-19
  • Tea Polyphenols and Effects
  • Plant Toxicity and Pharmacological Properties
  • Moringa oleifera research and applications
  • Phytochemicals and Medicinal Plants
  • Head and Neck Surgical Oncology
  • Trauma and Emergency Care Studies
  • Cervical Cancer and HPV Research

Aga Khan University
2025

University of Poonch Rawalakot
2020-2022

Pir Mehr Ali Shah Arid Agriculture University
2017-2022

University of Azad Jammu and Kashmir
2020-2022

East Suffolk and North Essex NHS Foundation Trust
2021

Emory University
2018

University of the Punjab
2018

Cranbrook Academy of Art
2005

Recently, an interest has surged in utilizing indigenous medicinal plants to treat infectious illnesses and extract bioactive substances, highlighting the need analyze for phytochemicals bioactivities. The present study was aimed evaluate impact of different solvent systems (aqueous, ethanol, methanol) used extraction on total phenolics, flavonoids, antioxidant, antibacterial activity three Azad Kashmir (Achillea millefolium, Bergenia ciliata, Aloe vera). High phenolic content found methanol...

10.1186/s13065-022-00858-2 article EN cc-by BMC Chemistry 2022-08-27

Local people in the Sudhnoti district of Pakistan share a rich practice traditional medicine for treatment variety ailments. We selected nine plants from ethnopharmacological tradition used infectious and inflammatory disease. Our aim was to evaluate vitro anti-infective potential extracts these species against multidrug-resistant (MDR) ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa, Enterobacter species) pathogens....

10.3389/fphar.2018.00815 article EN cc-by Frontiers in Pharmacology 2018-08-02

Pseudomonas aeruginosa (P. aeruginosa), one of the dangerous multidrug resistance pathogens, orchestrates virulence factors production through quorum sensing (QS). Since exploration QS inhibitors, targeting to circumvent bacterial pathogenesis without causing significant growth inhibition is a promising approach treat P. infections. The present study has evaluated anti-QS and anti-infective activity epigallocatechin-3-gallate (EGCG), bioactive ingredient traditional green tea, against...

10.3390/ijms22094946 article EN International Journal of Molecular Sciences 2021-05-06

Abstract In this study, we reported an easy, rapid, cost-effective and environmentally benign method for the fabrication of silver nanoparticles (Ag-NPs) using Olea ferruginea as reducing, capping stabilizing agent. For this, aqueous extract leaf bark O. was treated with 1 mM AgNO 3 , which reduces Ag ions to Ag-NPs by establishing reddish brown color. The synthesized were spherical crystals, a mean size 23 17 nm leaf- bark-mediated Ag-NPs, respectively. Fourier transform infrared...

10.1515/gps-2020-0047 article EN cc-by Green Processing and Synthesis 2020-08-20

Abstract Background This is the first comprehensive report on traditional and novel uses of medicinal plants practiced by indigenous communities Sudhnoti district Azad Jammu Kashmir (AJK), Pakistan. The area rich in folklore knowledge due to a unique tribal composition socioeconomic conditions. study aimed document native plant use local communities, particularly those used for therapeutic purposes. Methods Field surveys were conducted from September 2015 March 2017. Interviews with 125...

10.1186/s13002-021-00435-2 article EN cc-by Journal of Ethnobiology and Ethnomedicine 2021-03-20

The superbug Pseudomonas aeruginosa is among the most formidable antibiotic-resistant pathogens. With declining options for infections, new medicines are of utmost importance to combat with P. aeruginosa. In our previous study, we demonstrated that Epigallocatechin-3-gallate (EGCG) can inhibit production quorum sensing (QS)-regulated virulence factors in vitro. Accordingly, protective effect and molecular mechanisms EGCG against aeruginosa-induced pneumonia were studied a mouse model....

10.3389/fmicb.2022.874354 article EN cc-by Frontiers in Microbiology 2022-04-25

The COVID-19 pandemic is a catastrophic global phenomenon, affecting human life in way unseen since the 1918 influenza pandemic. Effective management of this threat requires halting transmission, strategy requiring accurate knowledge SARS-CoV-2 transmission patterns.This was retrospective contact study aiming to estimate rate by tracing contacts symptomatic, pre-symptomatic, and asymptomatic patients. History patients' during 24 h before appearance symptoms or infection confirmation traced...

10.1186/s12985-021-01609-w article EN cc-by Virology Journal 2021-07-03

Abstract Objective To evaluate the antioxidant activities and to identify bioactive compounds in hot water extracts of Terminalia chebula fruit. Methods The were determined by DPPH assay, lipid peroxidation iron chelation total assay. phenolic composition was HPLC-DAD. Human Rab8b Protein used for validation as anti-inflammation. String analysis protein synergism used. Results Retzius (Combretaceae) phenolics showed anti-inflammatory effect. specific compositions high performance liquid...

10.1186/s40816-020-00233-5 article EN cc-by Clinical Phytoscience 2020-12-01

To assess the state of knowledge, perception, preparedness and satisfaction level health care personals (HCPs) in Azad Jammu & Kashmir (AJK) towards COVID-19.It was cross sectional survey conducted by personal interviews.The study interviewing 302 HCPs from 7 major district headquarter hospitals AJK May to September 2020. The questionnaire included 29 questions about demography, training, preparedness, knowledge awareness COVID-19. data encoded analyzed statistically.Majority respondents...

10.1016/j.cegh.2021.100783 article EN cc-by Clinical Epidemiology and Global Health 2021-06-01

Abstract Background: Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2, declared as “once-in-a-century” pandemic, has affected about entire human population. Till now, the most promising control strategy is to block transmission which will never be effective without completely knowing patterns. Methods: This was a retrospective case study aiming estimate and calculate rate of COVID-19 through pre-symptomatic asymptomatic patients. Contact history...

10.21203/rs.3.rs-198847/v1 preprint EN cc-by Research Square (Research Square) 2021-02-17

In order to document stomatal characters which are significant in taxonomy, a detailed microscopic study on leaf epidermis of the selected taxa from Asteraceae was carried out.The plant species were Sonchus oleraceus, Bidens bipinnata, Centaurea iberica,

10.26814/cps2017002 article EN cc-by-nc Communications in Plant Sciences 2017-01-01

Abstract Background: COVID-19, a novel disease, appeared in December 2019 China and rapidly spread across the world. This study aimed to investigate find out factors responsible for death of COVID patients by comparing with recovered patients. Methodology: A retrospective, case control was conducted from August 2020 October three hospitals Poonch division, AJK. Total 192 who have been admitted hospital symptoms COVID-19 positive PCR test, including 152 infection 40 died, were enrolled study....

10.21203/rs.3.rs-123226/v1 preprint EN cc-by Research Square (Research Square) 2021-01-25

Leaf micromorphological characters of the genus Adiantum L. were studied using standard protocols light microscopy (LM). The study was aimed at investigation morpho-anatomical variation in three species viz A. capillus veneris, venustum and incisum sampled along altitude as an ecological variable. Stomatal density, number type subsidiary cells, stomatal complex index through Results revealed that leaf length decreased with increase altitude. varied from anisocytic to diacytic veneris well...

10.22541/au.168754872.28066487/v1 preprint EN Authorea (Authorea) 2023-06-23

Background: Electrolyte and mineral imbalances are frequently observed in individuals with diabetes mellitus associated systemic complications, including cardiovascular renal risks. Despite their clinical significance, such remain underexplored the local population. Aim: To evaluate levels of serum electrolytes (Na⁺, K⁺, Cl⁻) minerals (Ca²⁺, Mg²⁺) diabetic non-diabetic to investigate correlation glycemic control disease progression. Method: A cross-sectional study was conducted involving 300...

10.53350/pjmhs2023170938 article EN Pakistan Journal of Medical & Health Sciences 2023-09-28

Testing for high risk human papillomavirus (HR-HPV) is increasing; however due to limitations in specificity there remains a need better triage tests. Research efforts have focused recently on methylation of genes which show promise as diagnostic classifiers.Methylation 26 genes: APC, CADM1, CCND2, CDH13, CDKN2A, CTNNB1, DAPK1, DPYS, EDNRB, EPB41L3, ESR1, GSTP1, HIN1, JAM3, LMX1, MAL, MDR1, PAX1, PTGS2, RARB, RASSF1, SLIT2, SOX1, SPARC, TERT and TWIST1 was measured by pyrosequencing cytology...

10.1016/j.otohns.2005.05.306 article EN Otolaryngology 2005-08-01
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