A5100676805- Bacteriophages and microbial interactions
- Fluoride Effects and Removal
- Microbial infections and disease research
- Per- and polyfluoroalkyl substances research
- Genomics and Phylogenetic Studies
- Bacterial biofilms and quorum sensing
- Effects and risks of endocrine disrupting chemicals
- Plant pathogens and resistance mechanisms
- Toxic Organic Pollutants Impact
- Antibiotic Resistance in Bacteria
- Bone and Dental Protein Studies
- Plant Pathogens and Fungal Diseases
- Insect Utilization and Effects
- Plant-Microbe Interactions and Immunity
- Bone Metabolism and Diseases
- Tea Polyphenols and Effects
- Constructed Wetlands for Wastewater Treatment
- Plant and Fungal Interactions Research
- Potato Plant Research
- Insect symbiosis and bacterial influences
- Innovative Educational Techniques
- Plant Virus Research Studies
- Advanced Glycation End Products research
- Medicinal Plants and Neuroprotection
- Turfgrass Adaptation and Management
Dalian Maritime University
2023-2024
Huazhong Agricultural University
2016-2022
Ministry of Agriculture and Rural Affairs
2021-2022
Sichuan Agricultural University
2021-2022
Nanjing University of Information Science and Technology
2022
Wuhan University of Science and Technology
2022
China West Normal University
2022
Harbin Medical University
2017
Chinese Center For Disease Control and Prevention
2017
United States Department of Agriculture
2016
With the prevalence of multidrug-resistant bacteria and clinical -acquired pathogenic infections, development quorum-sensing (QS) interfering agents is one most potential strategies to combat bacterial infections antibiotic resistance. Chinese herbal medicines constitute a valuable bank resources for identification QS inhibitors. Accordingly, in this research, some compounds were tested inhibition using indicator strains. Paeonol phenolic compound, which can effectively reduce production...
Pseudomonas aeruginosa (P. aeruginosa), one of the dangerous multidrug resistance pathogens, orchestrates virulence factors production through quorum sensing (QS). Since exploration QS inhibitors, targeting to circumvent bacterial pathogenesis without causing significant growth inhibition is a promising approach treat P. infections. The present study has evaluated anti-QS and anti-infective activity epigallocatechin-3-gallate (EGCG), bioactive ingredient traditional green tea, against...
Sclerotinia minor is a phytopathogenic fungus causing sclerotinia blight on many economically important crops. Here, we have characterized the biological and molecular properties of novel endornavirus, endornavirus 1 (SmEV1), isolated from hypovirulent strain LC22 S. minor. The genome SmEV1 12,626 bp long with single, large open reading frame (ORF), coding for putative protein 4020 amino acids. contains cysteine-rich region (CRR), viral methyltransferase (MTR), DEXDc, helicase (Hel),...
Temperate phages are considered as natural vectors for gene transmission among bacteria due to the ability integrate their genomes into a host chromosome, therefore, affect fitness and phenotype of bacteria. Many virulence genes pathogenic were identified in temperate phage genomes, supporting concept that play important roles increasing bacterial pathogenicity through delivery genes. However, little is known about attenuation virulence. Here, we report novel Bordetella bronchiseptica phage,...
Enterococcus faecalis is an opportunistic pathogen that causes illnesses ranging from urinary tract infections to sepsis in humans and animals. However, the overuse of antibiotics has increased rates drug resistance among E. isolates. Bacteriophages their derivatives have recently been identified as good candidates for treatment drug-resistant bacterial infections. Here, we isolated a virulent phage, PHB08, using double-layer plate method. The bioactivity phage was determined via one-step...
Developing quorum-sensing (QS) based anti-infection drugs is one of the most powerful strategies to combat multidrug-resistant bacteria. Paeonol has been proven attenuate QS-controlled virulence factors P. aeruginosa by down-regulating transcription QS signal molecules. This research aimed assess anti-virulence activity and mechanism paeonol against infection in vitro vivo . In this study, was found reduce adhesion invasion P.aeruginosa macrophages resist cytotoxicity induced reduced...
The emergence and worldwide spread of Methicillin-resistant Staphylococcus aureus (MRSA) pose a threat to human health. While bacteriophages are recognized as an effective alternative treat infections caused by drug resistant pathogens, some in particular the temperate bacteriophage may also influence virulence host bacteria distinct ways. In this study, we isolated vB_Saus_PHB21 from epidermal sample Siberian tiger (Panthera tigris altaica) using MRSA strain SA14 indicator. Our following...
As a novel alternative to perfluorooctanoic acid (PFOA), hexafluoropropylene oxide trimer (HFPO-TA) has been widely used and caused ubiquitous water pollution. However, its adverse effects on aquatic organisms are still not well known. In the present study, zebrafish at different life stages were exposed 0, 5, 50, 100 μg/L of HFPO-TA for 21 days investigate reproductive toxicity in zebrafish. The results showed that exposure significantly inhibited growth induced zebrafish, including...
ERA5 monthly averaged reanalysis data during 1979–2020 are used to analyze the anomalous characteristics of summertime circulation types over Eurasia and their connections with North Atlantic Oscillation (NAO) modulated by sea surface temperature (SST). A index (CI) is defined describe Eurasian mid-high latitude classify into a double-ridge type (DR-type) double-trough (DT-type). The results show that these closely related variation western Pacific subtropical high (WPSH), East Asian jet...
Abstract Background: Enterococcus faecalis is an opportunistic pathogen can cause a variety of diseases, such as urinary tract infections and wound in human animals. Recently, bacteriophages their derivatives represent good effect on fighting against bacterial infections. Methods: We isolated virulent E. using the double-layer plate method. The bio-activities phage were determined via one-step growth curve testing killing assays. Illumina HiSeq sequencing was performed to determine genetic...
Ninety-five single-sclerotium isolates were obtained from lettuce and weeds in three counties central China. They identified belonging to Sclerotinia minor based on colony morphology the S. minor-specific DNA marker. Mycelial compatibility groups (MCGs) mating type (MAT) alleles these determined using methods of paired cultures specific PCR, respectively, MCG data used calculate Shannon's H index (H) Simpson (S), thereby evaluating diversity minor. Eight MCGs (MCG1 MCG8) two MAT (Inv+, Inv-)...
HomePlant DiseaseVol. 106, No. 3High-Quality Genome Resource of the Phytopathogenic Fungus Sclerotinia minor LC41, Causal Agent Blight on Lettuce in China PreviousNext RESOURCE ANNOUNCEMENT OPENOpen Access licenseHigh-Quality ChinaDan Yang, Tao Luo, Jinfeng Wei, Chunxia Cao, Guoqing Li, and Long YangDan YangHubei Biopesticide Engineering Research Centre, Wuhan 430064, China, LuoThe State Key Laboratory Agricultural Microbiology Hubei Plant Pathology, Huazhong University, 430070, WeiThe...
To investigate the expressions of mRNA and protein p38, Osx, PI3K, Akt1 in rats bone with chronic fluorosis.Dental fluorosis were observed fluoride contents urine detected by fluorin-ion selective electrode. The morphologic changes ultrastructure rats' light electronic microscopy. PI3K immunohistochemistry real-time PCR, respectively. BALP BGP serum ELISA.The rates dental increased, increased compared to control group, difference was statistically significant (P < 0.05). trabeculae thickness...