A5100333807- Bacteriophages and microbial interactions
- Remote Sensing in Agriculture
- Spectroscopy and Chemometric Analyses
- Remote Sensing and Land Use
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Gut microbiota and health
- Coastal wetland ecosystem dynamics
- Remote Sensing and LiDAR Applications
- Smart Agriculture and AI
- Plant Water Relations and Carbon Dynamics
- Hydrology and Watershed Management Studies
- Land Use and Ecosystem Services
- Ecology and Vegetation Dynamics Studies
- Geological and Geochemical Analysis
- Environmental and Agricultural Sciences
- Identification and Quantification in Food
- Isotope Analysis in Ecology
- RNA modifications and cancer
- Geology and Paleoclimatology Research
- Marine and coastal ecosystems
- Viral gastroenteritis research and epidemiology
- Physiological and biochemical adaptations
- Microbial infections and disease research
- Geochemistry and Geologic Mapping
Changshu Institute of Technology
2025
Tianjin University of Traditional Chinese Medicine
2017-2024
Wuhan Institute of Bioengineering
2024
Beijing Forestry University
2015-2024
Jilin Agricultural University
2019-2024
Tianjin haihe hospital
2024
Yili Normal University
2024
Huazhong Agricultural University
2022-2024
Chengdu Medical College
2024
Johns Hopkins University
2023-2024
Abstract Anti‐adhesion therapies interfere with the bacterial adhesion to host and thus avoid direct disruption of cycles for killing, which may alleviate resistance development. Herein, an anti‐adhesion nanomedicine platform is made by wrapping synthetic polymeric cores outer membranes. The resulting bacterium‐mimicking nanoparticles (denoted “OM‐NPs”) compete source bacteria binding host. “top‐down” fabrication OM‐NPs avoids identification adhesins bypasses design agonists targeting these...
Abstract The rapid rise of antibiotic resistance and slow discovery new antibiotics have threatened global health. While novel phage lysins emerged as potential antibacterial agents, experimental screening methods for pose significant challenges due to the enormous workload. Here, first unified software package, namely DeepLysin, is developed employ artificial intelligence mining vast genome reservoirs (“dark matter”) lysins. Putative are computationally screened from uncharacterized...
Klebsiella pneumoniae and Pseudomonas aeruginosa are two leading causes of burn wound infections, pneumonia, urinary tract more severe invasive diseases, which often multidrug resistant (MDR) or extensively drug resistant. Due to this, it is critical discover alternative antimicrobials, such as bacteriophage lysins, against these pathogens. Unfortunately, most lysins that target Gram-negative bacteria require additional modifications outer membrane permeabilizing agents be bactericidal. We...
Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that has been linked to the dysbiosis of gut microbiome and virome. However, potential characterization virome in SLE patients needs be explored more extensively. Methods Herein, we analyzed viral community 16 31 healthy controls using both bulk virus-like particle (VLP)-based metagenomic sequencing their fecal samples. A total 15,999 non-redundant operational taxonomic units (vOTUs) were identified from assembled...
Rheumatoid arthritis (RA) is influenced by oral and gut bacteria; however, much less known about the relationship between or viromes RA. Here, we performed whole-oral- whole-gut-virome analyses based on shotgun sequencing of 497 samples. A comparative analysis in healthy controls untreated treated RA patients was performed, system interaction networks among viruses, bacteria, RA-associated clinical indices were constructed to address potential virome principal-coordinate analysis,...
Food allergies are a global concern, with β-lactoglobulin (β-LG) in bovine milk being major allergenic protein. This study investigated the effects of transglutaminase (TGase)-mediated crosslinking on antibody recognition capacity (ARC) and structural properties β-LG, aim developing hypoallergenic dairy products. β-LG solutions were treated TGase at varying concentrations (0, 5, 10, 15, 20 U/g) durations 6, 18, 24, 42 h), followed by analysis using electrophoresis, enzyme-linked...
In the context of China's ongoing development unconventional oil and gas reservoirs, horizontal well segmental fracturing technology currently holds a dominant position. Accurate effective monitoring fracture parameters production profiles is imperative for efficient resources. Tracer has emerged as pivotal method wells fractured in tight segments. This involves injection slow-release tracer particles into fracture, followed by continuous concentration during return period subsequent...
Abstract Trillions of viruses inhabit the gastrointestinal tract. Some them have been well-studied on their roles in infection and human health, but majority remains unsurveyed. It has established that composition gut virome is highly variable based changes diet, physical state, environmental factors. However, effect host genetic factors, for example ethnic origin, rarely investigated. Here, we characterized compared a cohort local Chinese residents visiting Pakistani individuals, each group...
Viruses in the human gut have been linked to health and disease. Deciphering virome is dependent on metagenomic sequencing of virus-like particles (VLPs) purified from fecal specimens. A major limitation conventional viral low recoverability genomes dataset. To develop an optimal method for amplification maximizing recovery genomes. We performed parallel virus enrichment DNA extraction generate ∼ 30 samples each 5 fresh specimens conducted experiments including 1) optimizing cycle number...
The geographical origin and the important nutrient contents greatly affect quality of red raspberry (RRB, Rubus idaeus L.), a popular fruit with various health benefits. In this study, chemometrics-assisted hyperspectral imaging (HSI) method was developed for predicting contents, including pectin polysaccharides (PPS), reducing sugars (RS), total flavonoids (TF) phenolics (TP), identifying RRB fruits. results showed that these in fruits had significant differences between regions ( P...
Undisturbed natural wetlands are important carbon sinks due to their low soil respiration. When compared with inland alpine wetlands, estuarine in densely populated areas subjected great pressure associated environmental pollution. However, the effects of water pollution and eutrophication on respiration mechanism have still not been thoroughly investigated. In this study, two representative zones a tidal wetland located upstream downstream were investigated determine organic its mechanism....