A5023063635- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Renal cell carcinoma treatment
- Ocular Oncology and Treatments
- Abdominal vascular conditions and treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- Liver physiology and pathology
- Radiomics and Machine Learning in Medical Imaging
- Ultrasound Imaging and Elastography
- Glioma Diagnosis and Treatment
- Surgical Simulation and Training
- Renal and Vascular Pathologies
- Tuberous Sclerosis Complex Research
- Immune cells in cancer
- MRI in cancer diagnosis
- Vascular Procedures and Complications
- Multiple Sclerosis Research Studies
- Central Venous Catheters and Hemodialysis
- Lung Cancer Treatments and Mutations
- Renal Transplantation Outcomes and Treatments
- State Capitalism and Financial Governance
- Retinal Development and Disorders
- Systemic Lupus Erythematosus Research
University of Miami
2021-2024
Icahn School of Medicine at Mount Sinai
2019-2020
SUNY Downstate Health Sciences University
2020
State University of New York
2020
Anna Needs Neuroblastoma Answers
2020
Florida College
2017-2018
University of Florida
2015-2018
Massachusetts General Hospital
2014
Background To apply quantitative whole‐brain T 1 ‐rho (T 1ρ ) and 2 imaging to the detection quantification of brain changes resulting from multiple sclerosis (MS). Methods Twenty‐three MS patients with clinically isolated syndrome (10) relapsing remitting (13) phenotypes, compared 24 age‐matched healthy controls were imaged at 3 Tesla. An axial ‐weighted three‐dimensional turbo spin echo sequence a variable flip angle fluid suppression was used. Spin‐lock times 0, 20, 40, 60, 80, 100 ms...
Hepatocellular carcinoma, historically, has had a poor prognosis with very few systemic options. Furthermore, most patients at diagnosis are not surgical candidates. Therefore, locoregional therapy (LRT) been widely used, strong data supporting its use. Over the last 15 years, there progress in available agents. This led to updated Barcelona Clinic Liver Cancer (BCLC) algorithm's inclusion of these new agents, advocacy earlier usage those who on LRT or have tumor characteristics that make...
<h3>Background</h3> MUM-LM are resistant to ICIs for several reasons including the prevalence of myeloid-derived suppressor cells (MDSCs). PFS has been limited, even with approved therapies such as tebentafusp (median 3.3 months) grade 3/4 AE rates typically >30%. TLR9 agonists capable MDSC polarization but drug delivery historically limited using an intra-tumoral approach. Pressure-enabled (PEDD<sup>TM</sup>) SD-101, a agonist, potential overcome these barriers improve outcomes....
Visceral artery pseudoaneurysm is a rare, life-threatening medical condition with high incidence of rupture and bleeding. At most institutions, endovascular intervention considered the first-line treatment surgical repair as secondary option. Percutaneous glue embolization emerging safe alternative technique for minimally invasive visceral pseudoaneurysms. This case series aims to promote percutaneous life-saving measure in cases where an approach cannot be performed successfully, patients...
To determine the risk of bleeding complications requiring intervention after transplant renal biopsy as a function age transplanted kidney at time procedure. A total 1017 patients who underwent ultrasound or CT-guided single institution over 4-year period (2019-2023) were retrospectively identified. Demographic and clinical data collected, including biopsy, number cores sampled, operator, complications. Differences in demographic among with without analyzed. Of patients, 233 had ≤ 3 months...
<h3>Background</h3> The hepatic tumor microenvironment (TME) is uniquely immunosuppressive in part because of myeloid-derived suppressor cells (MDSCs). This contributes to metastatic UM with liver metastases (LM) responding poorly anti-PD1 based therapy. Even tebentafusp, the only approved systemic therapy, 1-year OS rate 72% (median, 21.6 mos) treatment-naive HLA-A*02:01 positive pts a median PFS 3.3 months.<sup>1</sup> TLR9 agonist nelitolimod induced favorable myeloid polarization...
BACKGROUND: This is a prospective study to evaluate potential treatment toxicity and progression free survival (PFS) of low grade glioma patients treated with proton radiation therapy. METHODS: Twenty WHO II indicated for therapy (8 new high risk diagnoses; 12 recurrent/progressive disease) were enrolled on single arm trial receiving 54 Gy(RBE) in 30 fractions. Comprehensive baseline regular post evaluations neurocognitive function, neuroendocrine quality life (QOL) performed. RESULTS: All...
Ultrasound-guided vascular access is an increasingly popular technique due to its reduced complication and higher success rates. Commercially bought training phantoms allow providers develop tactile skills in a low-risk setting, but are also expensive poorly accessible. This study analyzes the efficacy of homemade, low-cost, gelatin-based central line models teach anatomy intravascular techniques physicians.A gelatin mold was created using mixture unflavored gelatin, hot water, psyllium husk...
Abstract Yttrium-90 (Y-90) trans-arterial radioembolization (TARE) is used in the management of unresectable hepatocellular carcinoma (HCC). During last 5 years, dosimetry software has been developed to allow for a more rigorous approach dose prescription Y-90 TARE. We present here case study 77-year-old woman diagnosed with HCC, who underwent TARE as bridge procedure liver resection. This clinical scenario represents unique opportunity illustrate predictive value dosimetric findings...