A5000038109- Acupuncture Treatment Research Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Acute Ischemic Stroke Management
- Neurological Disease Mechanisms and Treatments
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Neuroscience of respiration and sleep
- Flavonoids in Medical Research
- Inflammasome and immune disorders
- Infant Health and Development
- Ginger and Zingiberaceae research
- Dietary Effects on Health
- Nitric Oxide and Endothelin Effects
- Polysaccharides Composition and Applications
- Traditional Chinese Medicine Studies
- Traditional Chinese Medicine Analysis
- Phytoestrogen effects and research
- Renin-Angiotensin System Studies
- Nanoplatforms for cancer theranostics
- Cognitive Science and Mapping
- Axon Guidance and Neuronal Signaling
- Healthcare and Venom Research
- Neonatal and fetal brain pathology
- Immune cells in cancer
- Advanced Nanomaterials in Catalysis
Affiliated Hospital of Qingdao University
2005-2024
Qingdao University
2005-2024
Ningxia Medical University
2010-2023
Tianjin University of Traditional Chinese Medicine
2013
Chinese PLA General Hospital
2005
National Natural Science Foundation of China
2005
Heritage Christian University
2005
Background Intravenous thrombolysis and endovascular thrombectomy have been approved for acute ischemic stroke (AIS). However, only a minority of patients received these treatments in China. We aimed to evaluate the efficacy safety tirofiban with AIS who were not undergoing early recanalization treatments. Methods Patients mild-to-moderate [National Institutes Health Stroke Scale (NIHSS) score, 4–15] enrolled this study. due cardiogenic embolism excluded. Eligible within 12 h from symptom...
The aim of this study is to investigate the effect extracellular signal-regulated kinases 1/2 (ERK1/2) inhibitor, PD98059, on high blood pressure and related vascular changes. Blood was recorded, thicknesses renal small artery walls were measured ERK1/2 immunoreactivity erk2 mRNA in smooth muscle cells (VSMCs) endothelial detected by immunohistochemistry situ hybridization normotensive wistar kyoto (WKY) rats, spontaneously hypertensive rats (SHR) PD98059-treated SHR. Compared with...
Background To improve the outcomes of acute ischemic stroke (AIS), timely thrombolytic therapy is crucial. Series strategies were recommended to reduce door-to-needle (DTN) time for AIS. Mobile technologies are feasible and have been used in management various purposes. However, use smartphone platforms that integrate series through entire first aid process emergency AIS remains be verified. Objective This study aims describe utility application a platform report DTN patients with during its...
Hippocampal neuronal damage likely underlies cognitive impairment in vascular dementia (VaD). PPARγ coactivator-1α (PGC-1α) is a master regulator of mitochondrial biogenesis. However, the role and precise mechanism how PGC-1α alleviates hippocampal injury remain unknown. To address this question, HT-22 cells, an immortalized neuron cell line, with or without overexpression were subjected to oxygen-glucose deprivation (OGD), which mimics circumstance chronic cerebral hypoperfusion VaD. After...
AIM:To study the protective effect of acupuncturing Tsusanli (S T 36) on cold stress ulcer, and expression nitric oxide synthase (NOS) in hypothalamus adrenal gland. METHODS:Ulcer index rats RT-PCR were used to acupuncture NOS gland.Images analyzed with semi-quantitative method. RESULTS:The ulcer significantly decreased ulcer.Plasma cortisol concentration was up regulated during stress, which could be depressed by pre-acupuncture.The NOS1 increased after acupuncture.The NOS2 related NOS3...
Morris水迷宫自英国心理学家Richard Morris于1981年首次使用以来,已成为一种研究与海马功能直接相关的空间学习记忆机制的标准模式,能较准确地反映动物的空间参考记忆能力[1].Morris水迷宫能为考察实验动物空间认知能力提供较多的评价指标,全面记录其认知加工过程,客观地反映其认知水平.但是,Morris水迷宫的实施过程中还有很多影响其准确性和可靠性的因素存在,如实验动物的选择、实验设计、实验的实施过程等.因此,笔者现就影响小鼠Morris水迷宫成绩的若干因素(Morris水迷宫自身因素及小鼠主观因素等)进行综述,以期为实验工作者们减少误差提供一些帮助. 关键词：Morris水迷宫;小鼠;学习记忆能力 分类号：R-332 文献标识码：A 文章编号：1671-8925(2013)08-0863-02
Abstract Our previous trial demonstrated that tirofiban was effective and safe in acute ischemic stroke (AIS) patients who were not undergoing early recanalization treatments. We aimed to further evaluate the structural MRI characteristics their clinical significance better predict guide treatment. In this post hoc analysis of imaging features, location infarcts (anterior circulation [ACS] vs posterior [PCS]), degree cerebral artery stenosis (≤ 69% ≥ 70% or occlusion), total infarct volume...
<sec> <title>BACKGROUND</title> To improve the outcomes of acute ischemic stroke (AIS), timely thrombolytic therapy is crucial. Series strategies were recommended to reduce door-to-needle (DTN) time for AIS. Mobile technologies are feasible and have been used in management various purposes. However, use smartphone platforms that integrate series through entire first aid process emergency AIS remains be verified. </sec> <title>OBJECTIVE</title> This study aims describe utility application a...