Xinxin Ding

ORCID: 0000-0003-1601-0871
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About
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Research Areas
  • Bone Tissue Engineering Materials
  • Dental Implant Techniques and Outcomes
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Titanium Alloys Microstructure and Properties
  • Electrospun Nanofibers in Biomedical Applications
  • Periodontal Regeneration and Treatments
  • Orthopaedic implants and arthroplasty
  • S100 Proteins and Annexins
  • Fuel Cells and Related Materials
  • Graphene and Nanomaterials Applications
  • Wound Healing and Treatments
  • Respiratory Support and Mechanisms
  • Advanced Photocatalysis Techniques
  • 3D Printing in Biomedical Research
  • Telemedicine and Telehealth Implementation
  • Advanced Drug Delivery Systems
  • Electrocatalysts for Energy Conversion
  • Facial Trauma and Fracture Management
  • Advanced Nanomaterials in Catalysis
  • Advanced battery technologies research
  • COVID-19 and Mental Health
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Hydrogels: synthesis, properties, applications
  • Bone health and osteoporosis research
  • Health and Wellbeing Research

Shanghai Ninth People's Hospital
2021-2025

Shanghai Jiao Tong University
2021-2025

National Clinical Research
2021-2025

National Clinical Research Center for Digestive Diseases
2021-2024

Shanghai Stomatological Hospital
2024

Jilin University
2018-2022

It is an effective way in bone tissue engineering to promote the mechanical and osteogenic capability of hydrogels by encapsulating mineral particles into polymer matrix. In this work, we reported novel kinds nanocomposite scaffolds based on hydroxypropyl chitosan/aldehyde dextran hydrogel (CDH) strontium-nanohydroxyapatite (Sr-nHA) nanoparticles. The molar ratios Sr/(Sr + Ca) at 0% (nHA), 50% (Sr50nHA), 100% (Sr100nHA) were fabricated subsequently incorporated CDH. characterization...

10.1021/acsbiomaterials.9b00584 article EN ACS Biomaterials Science & Engineering 2019-08-16

Guided tissue regeneration (GTR) is a promising treatment for periodontal defects, which generally uses membrane to build mechanical barrier from the gingival epithelium and hold space especially tooth-supporting bone. However, existing membranes possess insufficient properties limited bioactivity bone regenerate. Herein, fish collagen polyvinyl alcohol (Col/PVA) dual-layer were developed via combined freezing/thawing layer coating method. This had clear but contact boundary line between PVA...

10.3389/fbioe.2021.630977 article EN cc-by Frontiers in Bioengineering and Biotechnology 2021-06-09

A hydrogel with improved interfacial compatibility was formed to promote osteogenesis by establishing electrostatic bonds.

10.1126/sciadv.abj7857 article EN cc-by-nc Science Advances 2021-12-10

Excessive production of reactive oxygen species (ROS) around titanium implants under diabetic conditions causes persistent inflammation, leading to poor osseointegration and even implant failure. Surface modification is an effective way promote ROS clearance, alleviate stimulate bone formation. In this study, a multifunctional coating fabricated by introducing cerium (Ce)-containing mesoporous bioactive glass nanoparticles (Ce-MBGNs) onto the surface via electrophoretic deposition method....

10.1186/s12951-024-02865-y article EN cc-by-nc-nd Journal of Nanobiotechnology 2024-10-18

Neutrophils, as first-line immune cells, typically lose their edge within the diabetic wounds accompanied by methicillin-resistant Staphylococcus aureus (MRSA) infections (the D/M setting), playing role of "more foe than friend" during healing process. Specifically, reduced influx calcium ions (Ca2+) and impaired homeostasis yield dysfunction neutrophil sequential behaviors in pathogen killing wound healing, manifesting suppressed chemotaxis, decreased intracellular reactive oxygen species...

10.1021/acsnano.4c14057 article EN cc-by-nc-nd ACS Nano 2025-03-18

Abstract Titanium alloys are widely accepted as orthopedic or dental implant materials in the medical field. It is important to evaluate biocompatibility of an material prior use. A new β‐type ultrafine‐grained Ti–28Nb–2Zr–8Sn (TNZS) alloy with low Young's modulus 31.6 GPa was fabricated. This study aims TNZS alloy. In this study, we examined microstructure, chemical composition and surface wettability The mouse embryonic osteoblast MC3T3‐E1 cells human umbilical vein endothelial (HUVECs)...

10.1002/jbm.a.36679 article EN Journal of Biomedical Materials Research Part A 2019-03-28

Titanium (Ti) alloys are widely used in tissue engineering, but their applications limited by low strength, bactericidal properties, and metal ion release. Beta Ti promising materials for load‐bearing orthopedic implants due to excellent corrosion resistance high biocompatibility. Herein, developed new beta‐Ti including Ti–Nb–Zr–Sn (Ti–Sn) Ti–Nb–Zr–Ta–Si (Ti–Si) improve structural biochemical features of the existing as implants. The Ti–Sn Ti–Si were fabricated using mechanical ball milling...

10.1002/adem.202000430 article EN Advanced Engineering Materials 2020-10-16

10.5281/zenodo.6640942 article EN cc-by Zenodo (CERN European Organization for Nuclear Research) 2022-06-14
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