A5100452143- Air Quality and Health Impacts
- Liver Disease Diagnosis and Treatment
- Climate Change and Health Impacts
- Occupational and environmental lung diseases
- HIV, Drug Use, Sexual Risk
- Sleep and Work-Related Fatigue
- Cardiovascular Health and Disease Prevention
- Data-Driven Disease Surveillance
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Chronic Disease Management Strategies
- Impact of Light on Environment and Health
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Occupational exposure and asthma
- Nutritional Studies and Diet
- HIV/AIDS Research and Interventions
- COVID-19 diagnosis using AI
- Healthcare Systems and Public Health
- Autophagy in Disease and Therapy
- Adipose Tissue and Metabolism
- Heart Rate Variability and Autonomic Control
- Burn Injury Management and Outcomes
University of South Carolina
2018-2024
North China University of Science and Technology
2016-2024
First Affiliated Hospital of Fujian Medical University
2024
Fujian Medical University
2024
Center for Disease Control
2024
Tangshan People's Hospital
2024
Children's Medical Center
2022
Xinxiang Medical University
2020
National Cancer Institute
2001
National Institutes of Health
2001
Abstract Silicosis is a well‐acknowledged occupational lung disease caused by inhalation of large amount free silica dust during the production period and eventually considerable negative impact on patients' quality life. Autophagy exerts critical influence immune inflammatory responses pathogenesis pulmonary fibrosis. In this study, we sought to determine whether autophagy involved in silicosis's how it may affect cellular physiology. animal experiments, found persistent activation...
Linkage and retention in HIV medical care remains problematic the USA. Extensive health utilisation data collection through electronic records (EHR) claims represent new opportunities for scientific discovery. Big science (BDS) is a powerful tool investigating patterns. The South Carolina (SC) office of Revenue Fiscal Affairs (RFA) warehouse captures individual-level longitudinal persons living with (PLWH). includes EHR, from private institutions, housing, prisons, mental health, Medicare,...
The Chinese Visceral Adiposity Index (CVAI) is an indicator of visceral adiposity dysfunction used to evaluate the metabolic health population. Steelworkers are more likely be obese due their exposure special occupational factors, and have a higher prevalence carotid atherosclerosis (CAS). This study aimed analyze relationship between CVAI CAS among steelworkers. A total 4075 subjects from northern steel company were involved in cross-sectional study. Four logistic regression models...
Mycobacterium bovis BCG secretes two ATP‐scavenging enzymes, nucleoside diphosphate kinase (Ndk) and ATPase, during growth in Middlebrook 7H9 medium. In synthetic Sauton medium without any protein supplements, there is less secretion of these enzymes unless proteins such as bovine serum albumin (BSA), ovalbumin or extracts macrophages are added to the There a gradient activity among various triggering induction enzymes. Other mycobacteria, M. smegmatis , primarily secrete Ndk, while chelonae...
The Diverse Life-Course Cohort (DLCC) is a large-scale prospective study including around 130,000 participants in mainland China. primary aims of DLCC include contributing to knowledge on noncommunicable chronic disease determinants, particularly cardiometabolic diseases, and exploring the long-term effect ambient air pollutants or other environmental risk factors health among all-age populations. cohort consists several sub-populations that cover whole life-course diverse resources: from...
Abstract Background Obesity is increasingly recognized as a grave public health concern globally. It associated with prevalent diseases including coronary heart disease, fatty liver, type 2 diabetes, and dyslipidemia. Prior research has identified demographic, socioeconomic, lifestyle, genetic factors contributors to obesity. Nevertheless, the influence of occupational risk on obesity among workers remains under-explored. Investigating specific steelworkers crucial for early detection,...
Hyperuricemia has become the second most common metabolic disease in China after diabetes, and burden is not optimistic.We used method of retrospective cohort studies, a baseline survey completed from January to September 2017, follow-up March 2019. A group 2992 steelworkers was as study population. Three models Logistic regression, CNN, XG Boost were established predict HUA incidence steelworkers, respectively. The predictive effects three evaluated terms discrimination, calibration,...
Internet data are important sources of abundant information regarding HIV epidemics and risk factors. A number case studies found an association between internet searches outbreaks infectious diseases, including HIV. In this research, we examined the feasibility using search query to predict new diagnoses in China.We identified a set queries that associated with China. We developed statistical models (negative binomial generalised linear model its Bayesian variants) estimate by (Baidu)...
The misalignment between the circadian clock and behavioral cycles has been implicated in pathogenesis of many diseases. main purpose this study is to examine association rotating night shift work, exposure light at night, glomerular filtration rate among steelworkers north China. A total 6869 steelworkers, aged 22 60 years, were included study. Multivariable logistic regression was used brightness bedroom ambient (LAN), estimated (eGFR), with adjustment for potential confounders. Mediation...
Acquired Immune Deficiency Syndrome (AIDS) is still one of the most life-threatening diseases in world. Moreover, new infections are potentially increasing. This difficult problem must be solved. Early warning effective way to solve this problem. Here, we aim determine best performing model track epidemic AIDS, which will provide a methodological basis for testing time characteristics disease. From January 2004 2018, built four computing methods based on AIDS dataset: BPNN model, RNN LSTM...
The study designs a comprehensive evaluation system for the prevention and control of occupational hazards, calculates its weight coefficient, provides potential strategic effective tool scientific hazards in iron steel enterprises. was established through induction analysis relevant literature, personal interview, theoretical analysis, Delphi expert consultation, special group discussions. Using an improved analytical hierarchy process fuzzy model on basis investigation, operability index...
From the two perspectives of intestinal flora and plasma metabolomics, mechanism occurrence development pneumoconiosis was explored to provide a new target for prevention treatment pneumoconiosis. In this study, 16S ribosome DNA (16SrDNA) gene sequencing technology used analyze differences in each research group through operational taxonomic units (OUT) analysis, cluster principal component analysis (PCA), partial least square discriminant (PLS-DA), Kyoto Encyclopedia Genes Genomes (KEGG),...
This study aimed to investigate the association between metabolically healthy obesity (MHO) and carotid plaque. In this cross-sectional survey, 3467 steelworkers in North China were surveyed. There are two criteria for defining a plaque: (1) lesion structure exceeds 50% of peripheral intima-media thickness value or invades arterial lumen by at least 0.5 mm; (2) > 1.5 mm from intima−lumen interface media−adventitia interface. Metabolic health was defined as nonexistence one metabolic syndrome...
Coal workers are more likely to develop chronic obstructive pulmonary disease due exposure occupational hazards such as dust. In this study, a risk scoring system is constructed according the optimal model provide feasible suggestions for prevention of in coal workers. Using 3955 who participated health check-ups at Gequan mine and Dongpang Hebei Jizhong Energy from July 2018 August study subjects, random forest, logistic regression, convolutional neural network models established,...
Chronic obstructive pulmonary disease (COPD) represents a prevalent ailment, progressively surging within the ranks of coal mine laborers. The current study endeavors to elucidate effects dust exposure and smoking on COPD incidence amongst workers, while concurrently devising preventive strategies for this affliction.A nested case-control was conducted encompassing 1,416 participants aged ≥ 18 years, spanning duration from (2017-2018) until 2020. A meticulous matching process yielded cohort...
Occupational exposure to heat stress and noise at the workplace are widespread physical hazards have been associated with an increase in both morbidity mortality. This study aims examine association between occupational carotid atherosclerosis Chinese steelworkers. A total of 3471 subjects were included this study. Carotid plaque was measured using ultrasonography. The information collected by face-to-face personal interviews all reported verified company's records. Workers divided into...
Objective: To investigate the relationship between shift work and overweight/obesity in male steel workers. Methods: A questionnaire survey was conducted among workers selected during health examination Tangshan Steel Company from March 2015 to 2016. The were analyzed by using logistic regression model restricted cubic splinemodel. Results: total of 7 262 surveyed, overall prevalence overweight/obesitywas 64.5% (4 686/7 262), overweight rate 34.3% obesity 30.2%, respectively. After adjusting...
Objective: Analysis of geolocation-based social media Big Data provides unprecedented opportunities for a broad range domains including health as is intrinsically linked to the geographic characteristics places. HIV infection largely driven by risk behaviors, such unsafe sexual behavior and drug abuse/addiction. This study explores feasibility building Social media-based Risk Behavior (SRB) index at United States county level informing surveillance prevention, considering determinants...
This study aimed to investigate the prevalence of insomnia and risk factors among different job categories steel workers in China, order improve their quality occupational life.A cross-sectional face-to-face survey was conducted which involved 5834 from a large enterprise located northern including front-line, maintenance inspection, other auxiliary workers. The Athens Insomnia Scale Job Content Questionnaire were used assess status stress/social support, respectively. Multivariable logistic...
Exposure to light at night (LAN) can disturb circadian endocrine and metabolic rhythms. Hyperuricemia (HUA) is an early-onset disorder. However, it still not clear whether LAN exposure increases the prevalence of HUA.The authors used crosssectional data on Beijing-Tianjin-Hebei occupational populations cohort from March-July 2017. A total 7664 steel workers were finally selected investigate relationship between HUA among workers. The collected demographic socio-economic data, as well...