A5045571630- Exercise and Physiological Responses
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Liver Disease Diagnosis and Treatment
- Air Quality Monitoring and Forecasting
- Diet and metabolism studies
- Genetic Associations and Epidemiology
- Birth, Development, and Health
- Muscle Physiology and Disorders
- Pediatric health and respiratory diseases
- Pregnancy and preeclampsia studies
- Immune Cell Function and Interaction
- Coding theory and cryptography
- Antiplatelet Therapy and Cardiovascular Diseases
- Hepatitis C virus research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Chronic Disease Management Strategies
- Toxin Mechanisms and Immunotoxins
- Venous Thromboembolism Diagnosis and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Blood Coagulation and Thrombosis Mechanisms
- Cellular Automata and Applications
- Adipose Tissue and Metabolism
- Radiomics and Machine Learning in Medical Imaging
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
National Bureau of Statistics of China
2023
Soochow University
2019-2022
Yangtze River Pharmaceutical Group (China)
2020
National Taiwan University Hospital
2019
Sichuan University
2019
Hunan Agricultural University
2014-2015
First Affiliated Hospital of Fujian Medical University
2014
Fujian Medical University
2014
Institute of Subtropical Agriculture
2014
Abstract Background Hepatitis B virus (HBV) infection is a serious public health problem worldwide. This study aimed to investigate the relationship between serum alpha-fetoprotein (AFP) levels and pathological stages of liver biopsy in patients with chronic hepatitis (CHB). Methods The included 619 who were diagnosed CHB from March 2005 December 2011. AFP measured by electrochemiluminescence. Liver samples classified into five inflammation (G) fibrosis (S) stages, according Chinese...
The Diverse Life-Course Cohort (DLCC) is a large-scale prospective study including around 130,000 participants in mainland China. primary aims of DLCC include contributing to knowledge on noncommunicable chronic disease determinants, particularly cardiometabolic diseases, and exploring the long-term effect ambient air pollutants or other environmental risk factors health among all-age populations. cohort consists several sub-populations that cover whole life-course diverse resources: from...
Interleukin-15 (IL-15) is a cytokine highly expressed in skeletal muscle. The objective of the present study was to investigate development muscle IL-15 expression suckling piglets and early weaning (day 14) at each level, that is, mRNA, protein, secretion. Eight litters (eight per litter) newborn healthy (Large × White Landrace) with similar initial weight (1618.0 ± 140.1 g) were chosen divided into two groups. Group one used killed, respectively, days 1, 7, 14, 21, group killed 15, 17, 19,...
Background: Aspirin is the most commonly used antiplatelet agent for prevention of cardiovascular diseases. However, a certain proportion patients do not respond to aspirin therapy. The mechanisms non-response remain unknown. unique metabolomes in platelets with coronary artery disease (CAD) may be one causes resistance. Materials and methods: We enrolled 29 CAD who were non-responders, defined as study subject taking platelet aggregation time less than 193 seconds by PFA-100, 31 age-...
Objectives: The aim of this study was to explore spousal similarities in cardiovascular risk factors northern China. Methods: We conducted a cross-sectional married couples from Beijing, Hebei, Gansu, and Qinghai provinces between 2015 2019. A total 2,020 were included the final analyses. for metabolic indicators (including lifestyle cardiometabolic diseases) evaluated using Spearman's correlation logistic regression analyses, respectively. Results: All showed positive correlations (p <...
Background Studies comparing the effects of different sizes and concentrations ambient particulate matter (PM) on pulmonary function in regions sexes remain sparse. Objectives To investigate associations levels long-term PM exposure with among people typical areas South North China. Methods In 2021, a total 1,592 participants aged 20–73 years were recruited to participate test from baseline survey Diverse Life-Course Cohort (DLCC) Guangdong Province Hebei Province. The three-year (2018–2020)...
Background Variations in the prevalence and pattern of multimorbidity might be attributable to lifestyle environmental factors. This study was performed determine common chronic diseases reveal patterns among adults Guangdong province with Chaoshan, Hakka, island cultures. Methods We used data collected at baseline survey (April–May 2021) Diverse Life-Course Cohort included 5,655 participants aged ≥20 years. Multimorbidity defined as presence two or more 14 by self-reports, physical...
We developed a novel manganese (Mn 2+ ) chelate for magnetic resonance imaging (MRI) assessment of myocardial viability in acute and chronic infarct (MI) models, compared it with Gadolinium‐based delay enhancement MRI (Gd 3+ ‐DEMRI) histology. MI was induced 14 rabbits by permanent occlusion the left circumflex coronary artery. Gd ‐DEMRI Mn chelate‐based delayed chelate‐DEMRI) were performed at 7 days (acute MI, n = 8) or 8 weeks (chronic 6) after surgery sequential injection 0.15 mmol/kg...
Background . Magnesium lithospermate B (MLB) was shown to suppress oxidative stress and reduce hypertension, but the role of MLB in pregnancy-induced hypertension (PIH) remains unknown. The objective this study demonstrate effects on rats with PIH. Methods A total 40 pregnant SD were selected, 30 orally given NG-nitro-L-arginine methyl ester (L-NAME, 60 mg/kg/day) establish PIH rat models. Rats equally divided into four groups: control, PIH, 5 mg/kg MLB, 10 MLB. consecutively administered...
Effects of octenylsuccinate (OS) starch on body composition and intestinal environment in high-fat diet-fed mice were investigated. C57BL/6J treated with a regular-fat (RF) diet, (HF) or diet supplemented OS (HFOSS). Fecal short-chain fatty acids (SCFAs) quantified using gas chromatography, the fecal microbiota profile was analyzed by 16S rDNA sequencing. One-way ANOVA metastats analysis performed for statistical analysis. After 22 weeks feeding, HFOSS group had significantly lower weight,...
The Sysmex XN series haematopoietic progenitor cell (XN-HPC) is a novel tool for assessing stem yield before allogeneic transplantation. This study aimed to establish reference interval (RI) XN-HPC in peripheral blood transplant donors following granulocyte colony-stimulating factor (G-CSF) stimulation and determine its clinical significance. All specimens were analysed using XN-20. Samples collected non-parametric percentile methods define the RIs. Quantile regression was used explore...
Abstract Objective This study aimed to investigate the heritability of various obesity indices and their shared genetic factors with cardiometabolic traits in Chinese nuclear family. Methods A total 1270 individuals from 538 families were included this cross‐sectional study. Different used quantify fat mass distribution, including body index (BMI), visceral (VFI), percent (BFP). Heritability correlations for all quantitative estimated using variance component models. The...
Objective To study the causes and related factors of nosocomial infection after direct rooming-in management explore measurements to decrease incidence rate. Methods The data information was monitored analyzed retrospectively on basic nursing, patients behavior intervention, ward air disinfection, respiratory tract hand sanitary control medical care personnel in neonates moms with from January 2006 December 2009 hospital. Results 0.47%. Infected part mainly lower (38.1%).Conclusion...
Objective To investigate the significance of disease spread via blood testing to avoid occupational exposure among midwife and prevent nosocomial infection. Methods From September 2007 October 2009,serum hepatitis B virus surface antigen ( HBsAg ), antibody against C (anti-HCV), human immunodeficiency (anti-HIV)and toluidine red unheated serum test(TRUST) 3186 parturients were performed; incidence was statistically analyzed. Results The number percentage positive reaction for HBsAg,anti-HCV,...