Zhennan Lin

ORCID: 0000-0003-3602-7881
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About
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Research Areas
  • Air Quality and Health Impacts
  • Climate Change and Health Impacts
  • Air Quality Monitoring and Forecasting
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Diet and metabolism studies
  • Nutritional Studies and Diet
  • Genetic Associations and Epidemiology
  • Antibiotic Resistance in Bacteria
  • Natural Language Processing Techniques
  • Health, Environment, Cognitive Aging
  • Vibrio bacteria research studies
  • Healthcare Systems and Public Health
  • Acute Myeloid Leukemia Research
  • Global Health Care Issues
  • Sodium Intake and Health
  • Liver Disease Diagnosis and Treatment
  • Birth, Development, and Health
  • Lipoproteins and Cardiovascular Health
  • Virtual Reality Applications and Impacts
  • RNA modifications and cancer
  • Metabolomics and Mass Spectrometry Studies
  • Cancer, Lipids, and Metabolism
  • Antibiotics Pharmacokinetics and Efficacy
  • Stroke Rehabilitation and Recovery
  • Biochemical Analysis and Sensing Techniques

Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025

Peking Union Medical College Hospital
2025

Bioscience (China)
2022

Key Laboratory of Guangdong Province
2022

Soochow University
2019

Yanshan University
2018

Large Language Models (LLMs) have made significant progress in various downstream tasks, inspiring the development of Speech Understanding (SULMs) to enable comprehensive speech-based interactions. However, most advanced SULMs are developed by industry, leveraging large-scale datasets and computational resources that not readily available academic community. Moreover, lack transparency training details creates additional barriers further innovation. In this study, we present OSUM, an Open...

10.48550/arxiv.2501.13306 preprint EN arXiv (Cornell University) 2025-01-22

Introduction: Observational studies have linked loneliness or social isolation (SI) to ischemic heart disease (IHD), but results are inconsistent. Moreover, modifiable risk factors mediating the causal effects remain unclear. Hypothesis: and SI causally increase IHD risk, with metabolic behavioral acting as key mediators. Methods: Using genetic instruments derived from summary-level Genome-Wide Association Studies data of European ancestry, we performed a bidirectional two-sample Mendelian...

10.1161/cir.151.suppl_1.p3127 article EN Circulation 2025-03-11

Decline in pulmonary function contributes to increasing cardiovascular disease (CVD) risk. Although adverse effects of short-term exposure fine particulate matter (PM2.5) on have been recognized healthy people or patients with respiratory disease, these results were not well illustrated among elevated CVD A panel study was conducted three Chinese cities repeated visits populations at intermediate high-risk CVD, defined as treated hypertension those blood pressure ≥ 130/80 mmHg, who met any...

10.1016/j.ecoenv.2021.112397 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-06-08

Familial hypercholesterolemia (FH) is underrecognized, and its association with coronary artery disease (CAD) remains limited, especially in China. We aimed to investigate the prevalence of FH relationship CAD a large Chinese cohort.

10.1002/cdt3.69 article EN cc-by-nc-nd Chronic Diseases and Translational Medicine 2023-04-25

Abstract Background This study aims to assess the safety and efficacy of direct hemoperfusion using a new polymyxin B‐immobilized resin column (disposable endotoxin adsorber, KCEA) in an endotoxin/ lipopolysaccharide (LPS)‐induced sepsis model. Methods Eighteen beagles were randomized into 1 intervention group (KCEA group, n = 6) 2 control groups (sham model 6 each). Sepsis was induced by continuous intravenous application 0.5 mg/kg body weight for 60 min. An extracorporeal device made with...

10.1002/ame2.12199 article EN Animal Models and Experimental Medicine 2022-01-25

This paper presents a virtual reality training system for the lower limb rehabilitation robot, which can simulate bike riding and encourage patients to join in recovery through built-in competitive game. The is variable speed active under constraint trajectory, it has adapting posture function provide individual track according legs length of patients. movement synchronization between robot model achieved by interaction control strategy, change velocity based on signal from feedback terrains...

10.14419/ijet.v7i2.28.12892 article EN International Journal of Engineering & Technology 2018-05-16

Short-term PM2.5 exposure has been associated with hourly, 24-hour, daytime, and nighttime blood pressure (BP) levels, further studies focusing whether how the associations other ambulatory BP monitoring indicators are warranted.This study observed that short-term was elevations first to report of variability. Circadian rhythm load among hypertensive patients were found be modified by controlled status or taking angiotensin receptor blockers (ARBs).This suggested antihypertensive therapy,...

10.46234/ccdcw2021.231 article EN China CDC Weekly 2021-01-01
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