- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Disease and Adiposity
- Pediatric Hepatobiliary Diseases and Treatments
- Toxic Organic Pollutants Impact
- Cardiovascular Function and Risk Factors
- Ion channel regulation and function
- Chromatography in Natural Products
- Heavy Metal Exposure and Toxicity
- Plant-based Medicinal Research
- Genetic and Kidney Cyst Diseases
- Genetic Associations and Epidemiology
- Metalloenzymes and iron-sulfur proteins
- Effects and risks of endocrine disrupting chemicals
- Cardiovascular Health and Risk Factors
- Heparin-Induced Thrombocytopenia and Thrombosis
- Helminth infection and control
- Kawasaki Disease and Coronary Complications
- Liver Disease and Transplantation
- Cardiovascular Effects of Exercise
- Biliary and Gastrointestinal Fistulas
Shandong Provincial QianFoShan Hospital
2014-2024
Shandong First Medical University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2016-2023
Chinese Academy of Sciences
2022-2023
Chinese PLA General Hospital
2014-2023
National Astronomical Observatories
2022-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Beijing Anzhen Hospital
2022
Capital Medical University
2022
Beijing Institute of Water
2022
Percutaneous coronary intervention (PCI) of saphenous vein grafts (SVGs) has historically been associated with a high risk adverse ischemic events, but there is paucity contemporary data on the second-generation drug-eluting stent use within SVG, and relative importance platelet reactivity (HPR) in SVG PCI versus native lesion unknown. We studied bleeding events after their association HPR.Subjects prospective, multicenter ADAPT-DES study (Assessment Dual Antiplatelet Therapy With...
Background: Sleep is increasingly recognized as an important lifestyle contributor to health; however, its relationship with Motoric cognitive risk syndrome (MCR) still unclear. The present study aimed examine the associations between sleep duration, quality, and MCR among community-dwelling Chinese older adults. Methods: We recruited 5,387 participants aged ≥60 years from China Health Retirement Longitudinal Study (CHARLS). Sleep-related variables including night duration quality were...
RESULTS:Preoperative levels of cancer antigen 125 (12.51 ± 9.31 vs 23.20 21.86, P < 0.05) and carbohydrate 19-9 (22.56 26.30 72.55 115.99, were higher in the cystadenocarcinoma subgroup than cystadenoma subgroup.There no statistically significant differences age or gender between two groups, pre-or post-operative alanine aminotransferase, aspartate total bilirubin (TBIL), direct (DBIL) groups.However, eight 21 patients with six 25 had elevated TBIL DBIL.There three cases postoperative...
Conventional echocardiography is not sensitive enough to assess left ventricular (LV) dysfunction in hypertrophic cardiomyopathy (HCM) patients. This research attempts find a new ultrasonic technology better LV diastolic function, systolic and myocardial longitudinal circumferential strain of segments with different thicknesses HCM patients.This study included 50 patients 40 healthy subjects as controls. The peak early late mitral annulus velocities at six loci (Ea' Aa', respectively) the...
Diabetes mellitus (DM) is associated with an electrical remodeling of the heart, increasing risk arrhythmias. However, knowledge in sinoatrial node (SAN) by DM limited. We investigated expression HCN channel isoforms, HCN1-HCN4, SAN from streptozotocin (STZ)-induced diabetic rats and age-matched controls. found that STZ-induced have a lower intrinsic heart rate, lengthened conduction time, rate-corrected maximal recovery time vivo as well longer cycle length (CL) vitro, compared control....
Abstract Cadmium (Cd) is one of the most polluting heavy metal in environment. Cd exposure has been elucidated to cause dysfunction glomerular filtration barrier (GFB). However, underlying mechanism remains unclear. C57BL/6J male mice were administered with 2.28 mg/kg cadmium chloride (CdCl 2 ) dissolved distilled water by oral gavage for 14 days. The expression SDC4 kidney tissues was detected. Human renal endothelial cells (HRGECs) exposed varying concentrations CdCl 24 h. mRNA levels...
Background . Cholestasis is associated with high rates of morbidity and mortality in patients undergoing major liver resection. This study aimed to evaluate the effects a combined anisodamine neostigmine (Ani+Neo) treatment on inflammatory response regeneration rats obstructive jaundice (OJ) after partial hepatectomy. Materials Methods OJ was induced by bile duct ligation. After 7 days biliary drainage hepatectomy were performed. These assigned saline group or an Ani+Neo group. The...
The recurrence rate and readmission of patients with gallbladder stones cholecystitis are high. Endoscopic ultrasound-guided drainage (EUS-GBD) is a new method for the treatment in high surgical risk. acute symptoms can be relieved by bile, cholecystolithotomy or polyp resection performed through stent fistula. This article introduced technique EUS-guided conducted meta-analysis evaluating its feasibility safety. Four electronic databases including SinoMed, CNKI, Wanfang Data, PubMed were...
Objectives There are limited data on bivalirudin monotherapy in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) positive biomarkers of myocardial necrosis (troponin and/or creatine kinase-myocardial band isoenzyme). We sought to evaluate the safety and efficacy from Acute Catheterization Urgent Intervention Triage Strategy (ACUITY) trial. Patients methods compared net adverse clinical events [composite ischemia – (death, infarction, or unplanned ischemic...
Three-vessel disease (TVD) with a SYNergy between PCI TAXus and cardiac surgery (SYNTAX) score of ≥ 23 is one the most severe types coronary artery disease. We aimed to take advantage machine learning help in decision-making prognostic evaluation such patients.We analyzed 3786 patients who had TVD SYNTAX 23, no history previous revascularization, underwent either bypass grafting (CABG) or percutaneous intervention (PCI) after enrollment. The were randomly assigned training group testing...
Objective: To investigate the correlation between gastric bubble size and laryngopharyngeal reflux pattern in patients with disease(LPRD). Methods: A total of 52 LPRD who underwent Dx-pH monitoring anteroposterior chest radiography at same time from February 2016 to November 2018 were retrospectively studied. Patients devided into three position-related groups according Ryan score upright supine: isolated reflux(IUR), supine reflux(ISR) bipositional reflux(BR) groups. In addition, 13 healthy...
Inflammation increases the risk of thrombosis in coronary artery disease (CAD) patients and affects antiplatelet efficacy clopidogrel. C1q interacts with platelets to activate induce by participating regulating inflammatory response. Whether adenosine diphosphate (ADP)-induced platelet reactivity during clopidogrel therapy was unclear our study aimed explore issue. We enrolled 1,334 CAD receiving evaluated association between level high residual (HRPR) using logistic regression restricted...
ObjectivesTo describe long-term antithrombotic management patterns (AMPs) in medically managed Asian patients with non-ST-segment myocardial infarction (NSTEMI) or unstable angina (UA).BackgroundCurrent guidelines support an early invasive strategy NSTEMI and UA patients, but many are managed, data limited on AMPs Asia.MethodsData were analyzed from included the prospective, observational EPICOR Asia study (NCT01361386). Survivors to hospital discharge enrolled (June 2011 May 2012) 8...
Objective To examine the pathological changes in myocardial tissues such as inflammatory response and fibrosis a rat model of acute radiation-induced heart damage (RIHD), to explore whether NF-κB its downstream pathway are associated with fibrosis. Methods Fourteen male adult Sprague-Dawley rats were randomly divided into control group radiation group. Local irradiation was delivered precordial region establish an RIHD single fraction dose 20 Gy generated by 6 MV linear accelerator....
Coronary artery disease, fatty liver cardiac abnormalities, the metabolic syndrome, and insulin resistance may all occur in association with an increase of epicardial adipose tissue volume (EATV). Previous studies have shown that some cardiovascular-risk factors healthy behaviors were related to a lower risk EATV increase. The main purpose this study was determine whether ideal cardiovascular health (CVH) metrics correlated prevalence high EATV.The commenced across 2013 2014 involved...