A5100396467- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Blood Pressure and Hypertension Studies
- Cardiovascular Disease and Adiposity
- Cardiomyopathy and Myosin Studies
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Lipid metabolism and disorders
- ECG Monitoring and Analysis
- Cardiovascular Health and Disease Prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Health Promotion and Cardiovascular Prevention
- S100 Proteins and Annexins
- Congenital heart defects research
- Autoimmune Bullous Skin Diseases
- Nutritional Studies and Diet
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Cancer-related molecular mechanisms research
- Lipoproteins and Cardiovascular Health
- Cardiovascular Effects of Exercise
- EEG and Brain-Computer Interfaces
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Hunan Academy of Traditional Chinese Medicine
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
First Affiliated Hospital of Hebei Medical University
2022-2024
Affiliated Hospital of Hebei University
2024
China University of Petroleum, East China
2024
National Clinical Research Center for Digestive Diseases
2024
Shanghai Tenth People's Hospital
2021-2024
Tongji University
2021-2024
Hebei Medical University
2023-2024
Academy of Medical Sciences
2023
Hypertension is one of the major risk factor for cardiovascular disease worldwide. The objective this study was to investigate prevalence, awareness, treatment, and control hypertension in China. A multistage, stratified sampling method used obtain a representative sample persons aged 18 years or older general population Blood pressure (BP) measured by sphygmomanometer 3 times at 5-minute intervals. defined as systolic BP ≥ 140mm Hg, diastolic 90mm self-reported use antihypertensive...
Early diagnosis of acute ST-segment elevation myocardial infarction (STEMI) and early determination the culprit vessel are associated with a better clinical outcome. We developed three deep learning (DL) models for detecting STEMIs vessels based on 12-lead electrocardiography (ECG) compared them conclusions experienced doctors, including cardiologists, emergency physicians, internists. After screening coronary angiography (CAG) results, 883 cases (506 control 377 STEMI) from internal...
Objectives This study aimed to develop a patient-reported questionnaire assess service utilization and patient satisfaction among older adults with hypertension diabetes in primary health-care centers operating under China’s National Essential Public Health Service Program (NEPHSP). Methods The questionnaire’s item pool was constructed on the basis of logic model. A cross-sectional survey conducted three provinces mainland China between November December 2019. evaluated using Cronbach’s...
Background: Left bundle branch area pacing (LBBAP) is a recently proposed method for conduction system pacing. We performed meta-analysis of controlled studies to compare the clinical outcome in patients who received LBBAP vs. biventricular (BVP) cardiac resynchronization therapy (CRT). Methods: PubMed, Embase, and Cochrane's Library databases were searched relevant studies. A random-effect model incorporating potential heterogeneity was used synthesize results. Results: Four non-randomized...
Objective Coronary microvascular dysfunction (CMD) may associate with adverse cardiovascular events in obese patients. angiography-derived index of microcirculatory resistance (caIMR) is proposed as a less-invasive and pressure-wire-free to assess CMD. We aimed investigate the impact coronary function assessed by caIMR patients overweight chronic syndrome (CCS). Methods CCS who underwent angiography between 2015 2018 were included. Overweight was defined BMI≥24.0kg/m². Impaired caIMR≥25U....
Background: The liver is the central metabolic organ of animals. In chicken, knowledge on relationship between gene expression in and fat deposition during development still limited. A time-course transcriptomic study from embryonic (day 12) to egg-producing period 180 after hatch) was performed profile slow-growing meat type chicken investigate its correlation with abdominal deposition. Results: transcriptome profiles showed a separation different developmental stages. total, 13,096 genes...
Conventional echocardiography is not sensitive enough to assess left ventricular (LV) dysfunction in hypertrophic cardiomyopathy (HCM) patients. This research attempts find a new ultrasonic technology better LV diastolic function, systolic and myocardial longitudinal circumferential strain of segments with different thicknesses HCM patients.This study included 50 patients 40 healthy subjects as controls. The peak early late mitral annulus velocities at six loci (Ea' Aa', respectively) the...
Purpose: We developed a contrast agent for targeting E-selectin expression. detected the using magnetic resonance imaging (MRI) in vivo nude mice that had undergone nasopharyngeal carcinoma (NPC) metastasis. Methods: Sialyl Lewis X (sLeX) was conjugated with ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles. Hydrodynamic size, polydispersity index, and ζ-potential of USPIO-polyethylene glycol (PEG) nanoparticles USPIO-PEG-sLeX were measured. Component changes USPIO, USPIO-PEG,...
A WGAN-GP-based ECG signal expansion and an SE-ResNet1D-based classification method are proposed to address the problem of poor modeling results due imbalanced sample distribution data sets. The network architectures WGAN-GP SE-ResNet1D designed according characteristics signals so that they can be better applied generation signals. First, were generated using on MIT-BIH arrhythmia database balance dataset. Then, experiments performed AAMI category inter-patient partitioning principles,...
Hypertrophic cardiomyopathy (HCM) is the most common monogenic inherited myocardial disease in children, and mutations sarcomere genes (such as MYH7 MYBPC3) are genetic etiology of HCM, among which gene account for 30%-50%. have characteristics being affected by environmental factors, coexisting with multiple variations, age-dependent penetrance, leads to different or overlapping clinical phenotypes including various cardiomyopathies skeletal myopathies. At present, pathogenesis, course,...
Bacterial meningitis is currently recognized as one of the most important life-threatening infections central nervous system (CNS) with high morbidity and mortality, despite advancements in antimicrobial treatment. The disruption blood–brain barrier (BBB) induced by bacteria crucial for development bacterial meningitis. However, complete mechanisms involving BBB remain to be elucidated. Here, we found meningitic Escherichia coli induction angiopoietin-like 4 (ANGPTL4) brain microvascular...
Metabolic syndrome (MS) is a combination of symptoms characterized by central obesity, hypertension, hyperglycemia, and hyperlipidemia, which together increase the risk heart disease, stroke diabetes. In our study, we hypothesized that an EET-agonist (AUDA) would expression PGC 1α improve mitochondrial endothelial functions, resulting in improved function rat model MS. To investigate this, rats were randomly divided into four groups: 1) Control; 2) MS + ABCT; 3) AUDA; 4) AUDA SnMP. fed...
Abstract Postoperative atrial fibrillation (POAF) is a serious yet common complication after coronary artery bypass grafting (CABG) surgery. Previous study have identified multiple genetic susceptibility loci for POAF CABG, although some studies are under-powered. However, none of these been conducted among Asians. In current study, we aim to systematically evaluated the previous positive findings CABG Chinese population, using large population-based, two-stage, case-cohort study. From...
Hypertension is a major global health concern, and lifestyle modifications have been recommended as first-line treatment for hypertension in many guidelines. However, different guidelines may recommend types of adjustment, it unclear which ones are most effective. In this review, we compared to identify any differences and/or consensus content, efficacy, timing initiation modifications.We conducted search databases available English. We extracted information about by the guidelines.Five from...
Myxopapillary ependymomas (MPEs) are low-grade neuroepithelial tumors typically occurring in the conus - cauda equina filum terminale region. Limited molecular and cytogenetic analysis of MPEs has not demonstrated consistent abnormalities. In an attempt to clarify chromosomal status these identify commonly aberrant regions genome we have combined 3 molecular/cyto/genetic methods study 17 MPEs. Comparative genomic hybridization 7/17 identified concurrent gain on chromosomes 9 18 as most...
Higher levels of serum alkaline phosphatase (ALP) as a novel risk factor was recently found associated with mortality in different population, whereas, the relationship remains unknown hypertrophic cardiomyopathy (HCM) population. In this study, we hypothesized that increased ALP could predict all-cause adult HCM cohort retrospective data from 538 patients consecutively recruited West China Hospital were collected. Patients divided into two groups by baseline 80 IU/L cutoff. All-cause set...