A5036003598- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Aortic aneurysm repair treatments
- Cardiac Structural Anomalies and Repair
- Infectious Aortic and Vascular Conditions
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
- Neuroendocrine Tumor Research Advances
- Dialysis and Renal Disease Management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Pregnancy and Medication Impact
- Microscopic Colitis
- Potassium and Related Disorders
- Cardiac Ischemia and Reperfusion
Essen University Hospital
2017-2025
West German Heart and Vascular Center Essen
2017-2025
University of Duisburg-Essen
2018-2021
Osaka University
2020
Deutsches Herzzentrum München
2014-2015
Minimal access aortic valve replacement has become routine in many institutions. Aim of this study was to compare the clinical outcomes between conventional and minimal replacement. We retrospectively analysed data 2103 patients who underwent primary, isolated (AVR) our institution January 2001 May 2012 with a AVR (MAAVR) via upper partial ministernotomy approach ( n = 936) or (CAVR) full sternotomy 1167). After propensity score matching considering potential confounders [age, sex (female),...
Abstract Post-cardiotomy cardiogenic shock (PCCS) is a critical condition characterized by persistent low cardiac output syndrome (LCOS) that manifests either as an inability to wean from cardiopulmonary bypass (CPB) or severe dysfunction in the immediate postoperative period despite optimal medical therapy. With incidence of 2% 20%, PCCS associated with high morbidity, mortality, and healthcare resource utilization. This review explores pathophysiology while emphasizing mechanisms such...
Frozen elephant trunk (FET) is considered to be the treatment of choice in complex multi-segmental thoracic aortic disease involving distal arch. Institutional results FET technique are presented.From January 2005 October 2017, 286 patients underwent surgery our department. Patients (mean age 59±11 years) were operated for acute type I (55%) dissection (AD), chronic AD (23%) and aneurysm (22%). Arch repair was performed with E-vita Open prosthesis under selective cerebral perfusion...
Aortic valve construction using pericardial tissue has been known since the late 1960s. The procedure was re-introduced by Ozaki in 2010 and is currently used to treat specific aortic diseases. exact sizing of neo-cusps insertion commissures remain keys success when performing this procedure. We evaluated our experience modified custom-made templates.In prospective single-centre study, we 52 consecutive patients who underwent between September 2015 March 2017 either autologous (16 patients,...
Abstract A therapeutic dilemma arises when infective endocarditis (IE) is complicated by a neurologic event. Postponement of surgery up to 4 weeks recommended the guidelines, however, this negatively impacts outcomes in many patients with an urgent indication for due uncontrolled infection, disease progression, or haemodynamic deterioration. The current literature ambiguous regarding safety cardiopulmonary bypass recent injury. Nevertheless, most publications demonstrate lower risk secondary...
Abstract Myocardial revascularization in coronary artery disease via percutaneous intervention or bypass graft (CABG) surgery effectively relieves symptoms, significantly improves prognosis and quality of life when combined with guideline-directed medical therapy. Hybrid is a promising alternative to CABG selected patients defined as planned and/or intended combination consecutive using at least 1 internal mammary the left anterior descending (LAD), catheter-based non-LAD vessels for...
Methods to quantify mitochondrial function in translationally relevant models and human tissue are needed improve the translation of cardioprotection patients. Our present approach, using PMT instead isolated mitochondria for quantification ischemia-reperfusion damage, provides a reference further studies large animal tissue, thus possibly improving benefit patients with acute myocardial infarction.
Surgical treatment of patients with mitral valve regurgitation and advanced heart failure remains challenging. In order to avoid peri-operative low cardiac output, Impella 5.0 or 5.5 (5.x), implanted electively in a one-stage procedure, may serve as short-term mechanical circulatory support system (st-MCS) undergoing surgery.Between July 2017 April 2022, 11 consecutive underwent high-risk surgery for supported an 5.x (Abiomed, Inc. Danvers, MA). All were discussed the team either not...
Mitral valve repair (MVR) is considered the treatment of choice for mitral (MV) regurgitation. However, MVR in acute native MV infective endocarditis technically challenging and not commonly performed. Our goal was to report our outcomes endocarditis.Between January 2016 December 2017, 35 patients presenting with underwent MVR. Primary end points were successful freedom from recurrent endocarditis. Secondary point postoperative incidence major adverse events.The mean age 58 ± 13 years (74%...
Transcatheter aortic valve implantation (TAVI) is the standard therapy for high-risk patients with stenosis (AS). TAVI-outcomes are widely investigated in comparison to surgical replacement (SAVR), but less known about infectious complications after TAVI. We aimed compare early and mid-term outcomes of undergoing TAVI or SAVR.The present study a prospective single-centre including 200 consecutive between 06/2014-03/2015 (either transfemoral transapical transaortic, n=47+53=100) SAVR isolated...
Coronary endarterectomy (CEA) within coronary artery bypass grafting (CABG) is controversially discussed; however, CEA considered as a last option for severely diseased arteries. We therefore aimed to evaluate outcomes of patients undergoing CABG with CEA. present retrospective single surgeon's experience. Between 05/1999 and 12/2017, 426 underwent Follow-up imaging was proposed all surviving patients, only accepting were this study. This resulted in cohort 112 mean postoperative interval 53...
Ali Haddad, Ahmed Mohamed, Sven Arends, Bassam Ishak, Olga Tsarenko, Ilir Balaj, Markus Kamler, Thorsten Brenner, Sharaf-Eldin Shehada
Occlusion of the left atrial appendage (LAA) in patients with fibrillation has become a standard therapy to prevent thromboembolic complications. We aim present 3 cases LAA occluder embolization after percutaneous WATCHMAN™ device implantation, which required emergent surgical retrieval. The was dislocated atrium, introducing perforation and resulting pericardial effusion later tamponade 1 patient who developed multiorgan failure died 8 days postoperatively. Other were successfully operated...
The aim of this study is to report the preliminary real-word clinical and hemodynamic performance from MANTRA in patients undergoing aortic valve replacement with Perceval PLUS sutureless valve.
Objectives: We aimed to compare the in vitro flow dynamics of Perimount Magna Ease™ (PME) and Trifecta™ (TF) bioprostheses.Material methods: A new chamber was designed patterns PME (Edwards Lifesciences, Irvine, CA, USA) TF (SJM, St. Paul, MN, aortic valve prostheses. This channel offered possibility 2D-particle-image-velocimetry (2D-PIV) completely evaluate field downstream from middle arch. Maximum average velocities, vorticity, shear strength, maximum orifice diameters jet were analyzed....
Carcinoid heart disease (CHD) (Hedinger syndrome) is a rare manifestation, it has been described in up to 60% of patients with both neuroendocrine tumors (NETs) and carcinoid syndrome (CS) which, typically inducing right heart-sided abnormalities.Between 07/15 10/18, six (mean age 63±12 years; 3 females) presented manifested (NYHA III-IV) Hedinger syndrome's related valvular(s) lesion were operated at our center. Clinical data, adverse events patient outcomes recorded.The tricuspid valve was...
Objectives: During transcatheter aortic valve implantation (TAVI), ideal positioning is crucial. The latest-generation balloon expandable Sapien3™ heart (THV) comes with a marker, which recommended to be exactly centered at the annular level. We aimed evaluate higher "aortic" marker positioning.Material and methods: A total of 119 high-risk patients presenting stenosis were treated THV. After having placed THV more "aortic", clinical hemodynamic data, especially postoperative pacemaker...