Bilal Demir

ORCID: 0000-0003-1642-3481
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About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Nanoparticle-Based Drug Delivery
  • Conducting polymers and applications
  • Graphene and Nanomaterials Applications
  • Analytical Chemistry and Sensors
  • Nanoplatforms for cancer theranostics
  • Bone fractures and treatments
  • Essential Oils and Antimicrobial Activity
  • Electrochemical Analysis and Applications
  • Biosensors and Analytical Detection
  • Advanced Drug Delivery Systems
  • Advancements in Transdermal Drug Delivery
  • Supramolecular Self-Assembly in Materials
  • Photodynamic Therapy Research Studies
  • Molecular Junctions and Nanostructures
  • Dendrimers and Hyperbranched Polymers
  • Connective tissue disorders research
  • Bee Products Chemical Analysis
  • Carbon and Quantum Dots Applications
  • Silymarin and Mushroom Poisoning
  • Polymer Surface Interaction Studies
  • Nanofabrication and Lithography Techniques
  • Advanced Polymer Synthesis and Characterization
  • Connective Tissue Growth Factor Research

Université Polytechnique Hauts-de-France
2021-2025

Centre National de la Recherche Scientifique
2018-2025

Institut d'électronique de microélectronique et de nanotechnologie
2021-2025

Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2021-2025

Université de Lille
2021-2025

École Centrale de Lille
2021-2025

CEA Grenoble
2021-2025

Direction de la Recherche Technologique
2021-2025

University of Health Sciences Antigua
2021-2022

University of Health Sciences
2021

War against cancer constantly requires new affinity tools to selectively detect, localize, and quantify biomarkers for diagnosis or prognosis. Herein, carbon nanodots (CDs), an emerging class of fluorescent nanomaterials, coupled with molecularly imprinted polymers (MIPs), are employed as a biocompatible optical imaging tool probing biomarkers. First, N-doped CDs were prepared by hydrothermal synthesis using starch source l-tryptophan nitrogen atom provider achieve high quantum yield 25.1 ±...

10.1021/acsami.7b16225 article EN ACS Applied Materials & Interfaces 2018-01-04

Electroanalytical technologies as a beneficial subject of modern analytical chemistry can play an important role for abused drug analysis which is crucial both legal and social respects. This article reports novel aptamer-based biosensing procedure cocaine by combining the advantages aptamers selective recognition elements with well-known biosensor systems such possibility miniaturization automation, easy fabrication modification, low cost, sensitivity. In order to construct aptasensor...

10.1021/acs.analchem.6b00760 article EN Analytical Chemistry 2016-03-01

Expression of concern for ‘Innovative transdermal delivery insulin using gelatin methacrylate-based microneedle patches in mice and mini-pigs’ by Bilal Demir et al. , Nanoscale Horiz. 2022, 7 174–184, https://doi.org/10.1039/D1NH00596K.

10.1039/d5nh90011e article EN cc-by Nanoscale Horizons 2025-01-01

Over the past decade, there has been a great deal of interest in integration nanotechnology and carbohydrates.

10.1039/c7me00086c article EN Molecular Systems Design & Engineering 2017-10-18

The consumption of illicit drugs such as cannabis, cocaine, and amphetamines is still a major health social problem, creating an abuse in adults especially. Novel techniques which estimate the drug are needed for detection newly revealed psychoactive drugs. Herein, we have constructed combinatorial platform by using quantum dots (QDs) gold nanoparticles (AuNPs) well functional aptamer selectively recognizes cocaine its metabolite benzoylecgonine (BE). We called it folding-based sensory...

10.1002/dta.1992 article EN Drug Testing and Analysis 2016-06-23

A novel liposomal formulation was synthesized by encapsulating both gold nanoparticles (AuNPs) and<italic>Calendula officinalis</italic>extract as AuNP-phytosomes and were characterized used at<italic>in vitro</italic>investigations.

10.1039/c4ra05108d article EN RSC Advances 2014-01-01

In the ever-expanding field of conducting polymer research, functionalized graft hybrid copolymers have gained considerable interest in biomedical engineering and biosensing applications, particularly. present work, a new biosensor based on copolymer for detection phenolic compounds was developed. Thereby, robust novel material, namely "polythiophene-g-poly(ethylene glycol) with lateral amino groups" (PT-NH2-g-PEG) synthesized via Suzuki condensation polymerization characterized 1H NMR...

10.1021/acsami.5b04967 article EN ACS Applied Materials & Interfaces 2015-09-01

Two amphiphilic star-hyperbranched copolymers with different hydrophilic PHEMA segments were synthesized, and their drug loading/release profiles examined by using Paclitaxel.

10.1039/c5py00780a article EN Polymer Chemistry 2015-01-01

Herbal compounds, so-called phytoconstituents, illustrate poor absorption by living cells. Phytosomes are advanced form of herbal compounds that show higher rate and bioavailability, which results better than conventional plant extracts. Niosomes, made nonionic surfactants, create chemical stability conditions besides lipid vesicles. This study covers the preparation, characterization cell culture applications phyto-niosomes Marigold extract. Before encapsulation process, extracts selected...

10.1080/00914037.2015.1030663 article EN International Journal of Polymeric Materials 2015-05-21

Electrospun fiber mats loaded with therapeutics have gained considerable attention as a versatile tool in the biomedical field. While these bandages are largely based on fast-dissolving polymers to release cargo, stimuli-responsive advantages of providing timely and spatially controlled drug delivery platform, which can be refilled reused several times. These benefits make electrospun patches original platforms for painless convenient on-demand hormone release. Because high need more...

10.1021/acsabm.1c01161 article EN ACS Applied Bio Materials 2022-01-13

Because of the great achievement and progress made for generation novel nanostructures, theranostic nanoplatforms have been trending topic because their intensive capability therapy diagnosis. Hence, theranostics also recently a generic strategy personalized medicine. Moreover, traditional modalities limit use chemotherapeutic agents every patient, this requires more effective drug-carrier systems by designing formulation drug in specified way. Herein, we performed platform an "all-in-one"...

10.1021/acsanm.8b00468 article EN ACS Applied Nano Materials 2018-06-01

A folic acid (FA) modified poly(epsilon-caprolactone)/clay nanocomposite (PCL/MMT-(CH2CH2OH)2-FA) resulting in selective cell adhesion and proliferation was synthesized characterized as a culture biosensing platform. For this purpose, first the FA clay (MMT-(CH2CH2OH)2-FA) prepared by treating organo-modified clay, Cloisite 30B [MMT-(CH2CH2OH)2] with chloroform at 60 °C. Subsequent ring opening polymerization of ε-caprolactone presence tin octoate (Sn(Oct)2) using MMT-(CH2CH2OH)2-FA 110 °C...

10.1039/c4tb00850b article EN Journal of Materials Chemistry B 2014-01-01

The integration of drugs with nanomaterials have received significant interest in the efficient drug delivery systems. Conventional treatments therapeutically active may cause undesired side effects and, thus, novel strategies to perform these a combinatorial approach therapeutic modalities are required. In this study, polymethacrylic acid coated gold nanoparticles (AuNP-PMAA), which were synthesized reversible addition-fragmentation chain transfer (RAFT) polymerization, combined doxorubicin...

10.1021/acs.biomac.6b00706 article EN Biomacromolecules 2016-07-22

Trimethylamine (TM) intercalated montmorillonite (Mont) clay was prepared and characterized using X-ray diffraction, Fourier transform infrared spectroscopy, zeta potential thermal gravimetric measurements. Gluconobacter oxydans cells were immobilized on the micro-structured matrix used in microbial sensor applications. Sensor responses based respiratory activity of consumption oxygen monitored at −0.7 V (vs. Ag/AgCl platinum electrodes) by glucose as a substrate. Stabilization bacteria...

10.1039/c3ra40335a article EN RSC Advances 2013-01-01

The fabrication of electro and bioactive surfaces by electrochemical deposition the thiophene-functionalized polyphenylalanine macromonomer (T-g-PPhe) is reported. resulting conducting graft copolymer, polythiophene-graft-polyphenylalanine (PT-g-PPhe) formed on indium tin oxide (ITO) glass surface, characterized Fourier transform infrared spectroscopy, scanning electron microscopy, fluorescence microscopy. Then, possible uses PT-g-PPhe as matrices in sensor design for both biosensing cell...

10.1002/macp.201500219 article EN Macromolecular Chemistry and Physics 2015-08-19

N-Acetyl-l-cysteine (NAC)-capped poly(methyl methacrylate)-b-polycaprolactone block copolymer (PMMA-b-PCL-NAC) was prepared using the previously described one-pot photoinduced sequential CuAAC/thiol-ene double click procedure. PMMA-b-PCL-NAC had shown good applicability as a matrix for cell adhesion of cells from Vero line (African green monkey kidney epithelial). Here, in this work, served an excellent immobilization biomolecule conjugation. Covalent binding RGD (R: arginine, G: glycine,...

10.1002/mabi.201500099 article EN Macromolecular Bioscience 2015-05-13

Electrochemical detection of HeLa cancer cells with GCPE/AuNp/Cys/Glu/PAMAM/FA cytosensor.

10.1039/c5ra07893h article EN RSC Advances 2015-01-01

The present work is the first that includes use of glycine (Gly), lysine (Lys) and glutamic acid (Glu) modified clay mineral matrices in biosensors.

10.1039/c4ra07026g article EN RSC Advances 2014-01-01
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