A5101479841- Sphingolipid Metabolism and Signaling
- Iron oxide chemistry and applications
- Cancer, Hypoxia, and Metabolism
- Magnetic Properties and Synthesis of Ferrites
- Estrogen and related hormone effects
- Circular RNAs in diseases
- Geomagnetism and Paleomagnetism Studies
- Aquatic Ecosystems and Phytoplankton Dynamics
- Lipid Membrane Structure and Behavior
- Minerals Flotation and Separation Techniques
- Retinoids in leukemia and cellular processes
- Nanoplatforms for cancer theranostics
- Melanoma and MAPK Pathways
- Medicinal Plants and Bioactive Compounds
- Protein Kinase Regulation and GTPase Signaling
- Geological and Geochemical Analysis
- Synthesis and biological activity
- Traditional Chinese Medicine Studies
- Advanced biosensing and bioanalysis techniques
- Biological and pharmacological studies of plants
- Magneto-Optical Properties and Applications
- Hepatitis B Virus Studies
- Selenium in Biological Systems
- Calpain Protease Function and Regulation
- Silymarin and Mushroom Poisoning
University of South China
2022-2025
Hengyang Academy of Agricultural Sciences
2025
Chengdu University of Traditional Chinese Medicine
2010-2025
Second People’s Hospital of Yibin
2025
Shihezi University
2015-2022
Chongqing University of Arts and Sciences
2018-2022
First Affiliated Hospital of Shihezi University Medical College
2022
Temple University
2019
Sun Yat-sen University
2016
Wuhan University of Science and Technology
2009-2015
Abstract Circular RNAs are generated from many protein-coding genes, but their role in cardiovascular health and disease states remains unknown. Here we report identification of circRNA transcripts that differentially expressed post myocardial infarction (MI) mouse hearts including circFndc3b which is significantly down-regulated the post-MI hearts. Notably, human ortholog also cardiac tissues ischemic cardiomyopathy patients. Overexpression endothelial cells increases vascular growth...
Pure ferrimagnetic greigite (Fe 3 S 4 ) has been synthesized by reacting ferric chloride with thiourea and formic acid at 170°C. Sample purity was confirmed X‐ray diffraction, neutron diffraction Mössbauer spectroscopy, coupled magnetic measurements. Scanning electron microscope observations indicate clear cubo‐octahedral polyhedral crystal morphologies. The grain sizes are as large 44 μ m. Detailed low‐ high‐temperature measurements document the previously poorly known properties of...
Recent evidence suggests a role for aberrant ceramide levels in the pathogenesis of cancer and chemoresistance indicates that manipulation tumor may be useful strategy fight against breast cancer. This study demonstrates alterations degree position unsaturation bonds sphingoid backbone d-<i>erythro</i>-<i>N</i>-octanoyl-sphingosine (Cer) affect antiproliferative ability analogs cells. The most potent analog Cer we tested is...
The aim of present study was to evaluate the potential effects Rhodiola crenulata oral liquid (RCOL) on exhaustive exercise (EE)-induced fatigue in mice. Male Institute Cancer Research mice from five treatment groups (n=10 per group) were orally administered with sterilized water for Control and EE and/or RCOL at doses 1.02, 3.03 6.06 ml/kg/day, once daily 2 weeks. Anti-fatigue activity subsequently evaluated by measuring levels creatine kinase (CK), lactic acid (LA), lactate dehydrogenase...
One-dimensional wires of metallic nickel with width fluctuation were prepared in the presence magnetic fields, and chemical reduction [Ni(N2H4)x]2+ under fields was investigated.
Human glioma is the most common type of primary brain tumor and one invasive aggressive tumors, which, even with treatments including surgery, radiotherapy chemotherapy, often relapses exhibits resistance to conventional treatment methods. Developing novel strategies control human is, therefore, an important research focus. The present study investigated mechanism apoptosis induction in U251 cells by capsaicin (Cap) dihydrocapsaicin (DHC), major pungent ingredients red chili pepper, using...
Microcystin-LR (MC-LR) is a toxin that causes hepatic steatosis. Our previous study found exposure to 60 μg/L MC-LR for 9 months resulted in liver lipid accumulation, but the underlying mechanisms remain elusive. Herein, first time, fatty acid-targeted metabolome and RNA-seq were combined probe effect mechanism of chronic (12-month) treatment on mice metabolism at environmental-related levels (1, 60, 120 μg/L). It was dose-dependently raised serum levels. The total cholesterol (TC)...
Environmental estrogens represent a class of compounds which have been shown to mimic the effects or activity naturally occurring ovarian hormone 17β-estradiol. Given role 17β-estradiol in cell survival number systems, we wished determine if environmental protect MCF-7 cells from apoptosis. Here demonstrate that organochlorine pesticides o , p ′ DDT and alachlor, like 17β-estradiol, ability suppress tumor necrosis factor α (TNF)-induced apoptosis estrogen receptor (ER)-positive breast...
We provide comprehensive low‐temperature magnetic results for greigite (Fe 3 S 4 ) across the spectrum from superparamagnetic (SP) to multidomain (MD) behavior. It is well known that has no transitions, but we also document it strong domain‐state dependence of properties at low temperatures. Blocking SP grains and increasing thermal stability with decreasing temperature apparent in many measurements. Thermally stable single‐domain undergoes little change below room temperature. For...
A unique one-dimensional (1D) legume-like structure of cobalt nanoparticles was prepared by a simple magnetic-field-induced assembly approach with the assistance polyvinylpyrrolidone (PVP). In each 'legume', were regularly aligned along lines magnetic force in row visible spacing between adjacent and permanently linked PVP molecule layers order to maintain ordered shape after removal external field. Magnetic measurement showed that these structures superparamagnetic at room temperature,...
Mitochondria, as the powerhouse of most cells, are not only responsible for generation adenosine triphosphate (ATP) but also play a decisive role in regulation apoptotic cell death, especially cancer cells. Safe potential delivery systems which can achieve organelle-targeted therapy urgently required. In this study, effective pancreatic therapy, novel mitochondria-targeted and ROS-triggered drug nanoplatform was developed from TPP-TK-CPI-613 (TTCI) prodrug, ROS-cleave thioketal functions...
Considering that changes in the choroidal thickness are closely related to ocular growth, we studied (CT) and blood flow features children with unilateral myopic anisometropia (UMA) as well investigating relationship between myopia.
Previous studies have primarily concentrated on the hepatotoxicity of MC-LR, whereas its gastric toxicity effects and mechanisms long-term exposure under low dosage remain unknown. Herein, tissue from C57BL/6 mice fed with drinking water contaminated by low-dose MC-LR (including 1, 60, 120 μg/L) was investigated. The results obtained showed that to different concentrations resulted in significant shedding necrosis epithelial cells mice, a down-regulation tight junction markers, including...
Recent studies showed that benzimidazoleisoquinolinone derivatives exhibit anticancer activity against human cancer cell lines. The aim of this study is to evaluate the anti-tumor effects and mechanisms benzimidazoleisoquinolinones in isocitrate dehydrogenase-wildtype subtype glioblastoma (GBM) cells.Human U87 LN229 lines were used perform experiments. MTT was applied screen effective small molecular inhibitors suppressing growth GBM cells. Colony formation BrdU staining assays performed...
Quasi-aligned cylindrical and conical core-shell nanofibers consisting of carbon shells TiO(2) nanowire cores are produced in situ on Ti foils without using a foreign metallic catalyst template. A nanofiber has core 30-50 nm diameter 5-10 nm-thick shell, while the nanostructure 20-40 thickness shell varies from about 200 at bottom to 5 tip. Electrochemical analysis reveals well-defined redox peaks [Fe(CN)(6)](3-/4-) couple heterogeneous charge-transfer rate constants 0.010 0.062 cm s(-1) for...