- Enzyme Catalysis and Immobilization
- biodegradable polymer synthesis and properties
- Enzyme Production and Characterization
- Microplastics and Plastic Pollution
- Polyamine Metabolism and Applications
- Antimicrobial Peptides and Activities
- Studies on Chitinases and Chitosanases
- Nanocomposite Films for Food Packaging
- Nanoparticle-Based Drug Delivery
- Antimicrobial agents and applications
- Hemostasis and retained surgical items
- Enzyme Structure and Function
- Legume Nitrogen Fixing Symbiosis
- Graphene and Nanomaterials Applications
- RNA Interference and Gene Delivery
- Recycling and Waste Management Techniques
- Microbial Metabolites in Food Biotechnology
- Polymer Surface Interaction Studies
- Amino Acid Enzymes and Metabolism
- Pancreatic function and diabetes
- Protein Hydrolysis and Bioactive Peptides
- Surgical Sutures and Adhesives
- Supramolecular Self-Assembly in Materials
- Pineapple and bromelain studies
Nanjing Tech University
2014-2024
An<italic>in situ</italic>forming hydrogel derived from epsilon-poly-<sc>l</sc>-lysine was crosslinked by the enzymatic catalysis method and showed excellent antibacterial properties for wound infection prevention.
Trehalose is an important rare sugar that protects biomolecules against environmental stress. We herein introduce a dual enzyme cascade strategy regulates the proportion of cargos and scaffolds, to maximize benefits immobilization. Based upon self-assembling properties shell protein (EutM) from ethanolamine utilization (Eut) bacterial microcompartment, we implemented catalytic synthesis trehalose soluble starch with coimmobilization α-amylase synthase. This improved enzymatic activity...
In this study, novel bio-inspired in situ hydrogels as tissue adhesives and hemostatic materials were designed prepared based on ɛ-polylysine-grafted poly(ethylene glycol) tyramine via enzymatic cross-linking. The cross-linked method enabled fast gelation within seconds, which facilitated its therapeutic applications. By changing the cross-linking conditions, storage modulus of could be tunable mechanical strength influenced adhesiveness hydrogels. Besides, showed fine network structures...
Abstract As a rare low‐calorie sugar with special medicinal value, d ‐tagatose is widely used in the field of food, beverages, medicine, and cosmetics. However, enzymatic production vitro commonly limited to low conversion efficiency poor thermo‐stability. Herein, taking advantage self‐assembling property protein scaffold EutM (ethanolamine bacterial microcompartments), Spy Snoop peptide pairs was drive linkage between cargo proteins, β‐galactosidase (BagB), l ‐arabinose isomerase (TMAI)...
Much attention has been given to the problem of drug delivery through cell membrane in order treat and manage bone diseases recently. The aim this study was develop nanoparticles made amino- histidinyl-modified amphiphilic β-cyclodextrins (β-CDs) entrapping osteoclast inhibitor, a hydrophobic oligopeptides drug, across marrow-derived macrophages (BMMs). Drug-loaded β-CDs (NPs) were prepared by emulsion solvent evaporation technique fully characterized for size, zeta potential, entrapment...
The current issue of extensive polyethylene terephthalate (PET) usage in food packaging has resulted a significant problem microplastics (MPs) pollution. Recent research identified several PETases and their mutants that exhibit promising PET degradation capabilities. However, the limited reusability laborious purification steps involved process hinder practical application. In this study, we have introduced bacterial enzyme cascade reaction system (BECRS) emulates adsorption stages observed...