A5035752314- HIV, Drug Use, Sexual Risk
- Blood donation and transfusion practices
- HIV/AIDS Research and Interventions
- Food Allergy and Anaphylaxis Research
- Hepatitis C virus research
- Allergic Rhinitis and Sensitization
- Healthcare Systems and Practices
- Sex work and related issues
- Syphilis Diagnosis and Treatment
- Contact Dermatitis and Allergies
- Hepatitis B Virus Studies
- Immune Cell Function and Interaction
- HIV, TB, and STIs Epidemiology
- Sexuality, Behavior, and Technology
- Asthma and respiratory diseases
- Erythrocyte Function and Pathophysiology
- HIV Research and Treatment
- COVID-19 and healthcare impacts
- Neutropenia and Cancer Infections
- Adolescent Sexual and Reproductive Health
- Health, Medicine and Society
- Clinical practice guidelines implementation
- Hemoglobinopathies and Related Disorders
- Climate Change and Health Impacts
- Drug-Induced Adverse Reactions
Institut thématique Santé Publique
2016-2024
Santé Publique France
2016-2024
Hôpital Paris Saint-Joseph
2018-2022
Hôpitaux de Saint Maurice
2018-2021
Hôpitaux Universitaires de Strasbourg
2021
Hôpital Saint-Vincent-de-Paul
2010-2018
Groupe Hospitalier de l'Institut Catholique de Lille
2010-2017
Institut de Veille Sanitaire
2015-2016
Institut de Recherche pour le Développement
2012
Université Catholique de Lille
2012
The emergence of SARS-CoV-2 variant 20I/501Y.V1 (VOC-202012/1 or GR/501Y.V1) is concerning given its increased transmissibility. We reanalysed 11,916 PCR-positive tests (41% all positive tests) performed on 7-8 January 2021 in France. prevalence was 3.3% among nationwide and 6.9% the Paris region. Analysing recent rise 20I/501Y.V1, we estimate that, French context, 52-69% more transmissible than previously circulating lineages, depending modelling assumptions.
Over the last 20 years, Hepatitis C virus (HCV) infection prevalence has dramatically increased among HIV-infected men who have sex with (MSM) in many countries worldwide. It is suspected that this increase primarily driven by sexual behaviours linked to blood exposure. Monitoring these crucial understand drivers of epidemic. This study assessed chronic HCV MSM attending gay venues and associated risk factors. screening factors were described. The cross-sectional survey PREVAGAY, based on...
To evaluate trends over the last 18 years in HIV-related knowledge, risk perceptions, and sexual behaviors young adults. Data were obtained from six KABP (knowledge, attitudes, beliefs, practices) surveys (1992, 1994, 1998, 2001, 2004, 2010) representative samples of French population. Surveys similar terms data collection target populations: 2362 men 2774 women aged 18-29 interviewed by telephone. Young people very familiar with true routes HIV transmission throughout full period. However,...
Blood donation deferral for men who have sex with (MSM) in France was reduced from permanent to 12 months July 2016. To inform a further reduction of the period, an HIV risk assessment conducted two scenarios: S1, 4-month deferral; S2, only case more than one sexual partner (i.e., similar other blood donors).Baseline residual (RR) calculated 2016 December 2017, using Incidence Rate-Window Period method. The impact both scenarios on RR assessed data surveys MSM and donors, estimate 1) number...
Background. The Demographic Surveillance System established in 1962 Niakhar, Senegal, is the oldest Africa. Here, we analyze trends overall child mortality, malaria, and other causes of death Niakhar from beginning data collection to 2010. Methods. After an initial census, demographic were updated yearly 1963 through From 1984, determined by verbal autopsy technique. Results. During 1963–2010, infant under-5 mortality rates decreased 223‰ 18‰ 485‰ 41‰, respectively. decrease was progressive...
BackgroundSyphilis in blood donors (BD) has increased many countries.AimWe aimed to describe trends syphilis seroposivity BD France, identify risk factors and assess if a non-treponemic test (NTT) could define having recovered from for more than 1 year.MethodsThe analysis covered the period 2007 2022 45,875,939 donations. Of 474 syphilis-positive 2022, 429 underwent additional investigations with an NTT. History of was obtained at post-donation interview or based on serology results repeat...
BACKGROUND Blood donor selection, consisting of a pre‐donation questionnaire and interview, excludes potential donors who may be at risk transfusion‐transmissible infections. Assessing the reasons for noncompliance with blood selection criteria is important to maintain high level viral safety products. STUDY DESIGN AND METHODS An anonymous French online survey sample (Complidon) was conducted from September December 2017. Data were poststratified representative all donated between July 2016...
Since the advent of AIDS, men who have sex with (MSM) often been deferred from blood donation. In France, quarantine plasma donation by MSM donors same deferral rules as for other was introduced in July 2016 and continued up to March 2022. At this time, MSM-specific criteria were lifted all or The donor deferral, well rate infectious markers would otherwise activity, evaluated compared those during time period June 2022.A total 8843 made 12,250 applications. overall very high (75.2%), mainly...
Abstract Sex between men is the most frequent mode of HIV transmission in industrialised countries. Monitoring risk behaviours among who have sex with (MSM) crucial, especially to understand drivers epidemic. A cross-sectional survey (PREVAGAY), based on time-location sampling, was conducted 2015 MSM attending gay venues 5 metropolitan cities France. We applied generalised weight share method (GWSM) estimate seroprevalence for first time this population, taking into account frequency venue...
We evaluated the performance of a fourth-generation antigen/antibody (Ag/Ab) assay for detecting HIV-1 infection on dried blood spots (DBS) both in conventional laboratory environment and an epidemiological survey corresponding to real-life situation. Although 2-log loss sensitivity compared that with plasma was observed when using DBS analytical analysis, median delay positivity between crude serum during early phase postacute 7 days. The approximately similar third-generation (antibody...
Summary. The present report provides evidence that hydroxyurea (HU) improves the β thalassaemic phenotype in mice receiving 200 mg/kg/d for 30 d. haematocrit rose from 29·3% at day 0 to 37·4% ( P <0·05), despite myelosuppression and decreased reticulocyte counts. minor/α ratio of globin chain synthesis increased 0·78 0·97 <0·001). Membrane defects improved: proportion bound α chains decreased, spectrin ankyrin red cell deformability also increased.
Background and objectives In France, blood donation deferral for men who have sex with (MSM) was reduced from permanent to 12 months in July 2016. Assessing noncompliance (rate reasons) this criterion is important maintain a high level of viral safety products. Materials methods An anonymous online survey (Complidon) sample donors conducted 2017. Data were post‐stratified be representative all those donated between 2016 December A multivariable analysis performed assess factors associated...
<b><i>Introduction:</i></b> The coronavirus disease 2019 (COVID-19) pandemic continues to have great impacts on the care of non-COVID-19 patients. This was especially true during first epidemic peak in France, which coincided with national lockdown. aim this study identify whether a decrease stroke admissions occurred spring 2020, by analyzing evolution all France from January June 2020. <b><i>Methods:</i></b> We conducted nationwide cohort...
Abstract Background and Objectives In 2016, France allowed men who have sex with (MSM) to donate blood if they had not in the previous 12 months. April 2020, this restriction was relaxed 4 months due lack of negative impact observed on safety. This study assesses reducing deferral period epidemiological surveillance indicators. Materials Methods compares infection indicators between two 30‐month periods before (P1) after (P2) second change. Results Overall, 79 donations tested positive for...