A5079825521- Pharmaceutical Practices and Patient Outcomes
- Patient Safety and Medication Errors
- Primary Care and Health Outcomes
- Healthcare Policy and Management
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Technology
- Healthcare Quality and Management
- Medical Malpractice and Liability Issues
- Emergency and Acute Care Studies
- Clinical Reasoning and Diagnostic Skills
- Library Science and Administration
- Healthcare cost, quality, practices
- Pharmaceutical studies and practices
- Electronic Health Records Systems
- Medication Adherence and Compliance
- Diabetic Foot Ulcer Assessment and Management
- COVID-19 and healthcare impacts
- Nursing Roles and Practices
- COVID-19 Clinical Research Studies
- Antibiotic Use and Resistance
- Pharmacovigilance and Adverse Drug Reactions
- Health Promotion and Cardiovascular Prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Vaccine Coverage and Hesitancy
- Clinical practice guidelines implementation
University of Nottingham
2013-2025
Northern General Hospital
2024
University of Liverpool
2020-2022
Our Lady's Hospital
2021
Primary Health Care
2019
Queen's Medical Centre
1999-2018
University of Edinburgh
2018
Swansea University
2018
NIHR School for Primary Care Research
2018
Denver Public Health
2014-2015
There is evidence that patients are being prescribed potentially hazardous drug-drug combinations in general practice despite the use of computerized drug interaction alert systems. One reason for this may be practitioners (GPs) overriding these alerts without properly checking them.(i) To assess GPs views on relevance information provided by systems; (ii) determine proportion admit to frequently them and (iii) explore factors might associated with a tendency override alerts.Questionnaire...
Aims Thiazide diuretics have a number of well‐documented metabolic adverse effects. The aim this study was to estimate the frequency hyponatraemia and hypokalaemia amongst patients taking thiazide diuretic in primary care. Methods A computerized search electronic prescribing laboratory records six UK general practices performed. Of 32 218 adult identified, 3773 had received at least one prescription for between years 1990 2002. Results Detailed data were available 2942 whom 951 (32.3%)...
<b>Study question</b> What is the prevalence of different types potentially hazardous prescribing in general practice United Kingdom, and what variation between practices? <b>Methods</b> A cross sectional study included all adult patients at risk a or monitoring error defined by combination diagnoses prescriptions 526 practices contributing to Clinical Practice Research Datalink (CPRD) up 1 April 2013. Primary outcomes were anticoagulants, anti-platelets, NSAIDs, β blockers, glitazones,...
Objective To estimate the incidence of avoidable significant harm in primary care England; describe and classify associated patient safety incidents generate suggestions to mitigate risks ameliorable factors contributing incidents. Design Retrospective case note review. Patients with health problems were identified clinical judgements made on avoidability severity harm. Factors recorded. Setting Primary care. Participants Thirteen general practitioners (GPs) undertook a retrospective review...
Abstract Biochar has high potential for long-term atmospheric carbon storage in terrestrial environments, contributing to meeting the UK and global greenhouse gas emission reduction targets. This study investigates emissions techno-economics associated with biochar produced from food waste anaerobic digestate using hydrothermal carbonisation followed by high-temperature post carbonisation. Owing moisture contents, digestates are challenging valorise. However, these low-value feedstocks have...
The extent of preventable medication-related hospital admissions and issues in primary care is significant enough to justify developing decision support systems for medication safety surveillance. prerequisite such defining a relevant set safety-related indicators understanding the influence both patient general practice characteristics on prescribing monitoring.The aim study was investigate feasibility linked secondary electronic health record data surveillance safety, examining not only...
Abstract Background There is a need to shed light on the pathways through which complex interventions mediate their effects in order enable critical reflection transferability. We sought explore and understand key stakeholder accounts of acceptability, likely impact strategies for optimizing rolling-out successful pharmacist-led information technology-enabled (PINCER) intervention, substantially reduced risk clinically important errors medicines management primary care. Methods Data were...
The importance of engaging stakeholders in the research process is well recognised. Whilst engagement important, guidelines and practices vary for how should be involved to facilitate effective collaborative relationships.
Medication errors are an important cause of morbidity and mortality in primary care. The aims this study to determine the effectiveness, cost effectiveness acceptability a pharmacist-led information-technology-based complex intervention compared with simple feedback reducing proportions patients at risk from potentially hazardous prescribing medicines management general (family) practice.RESEARCH SUBJECT GROUP: "At-risk" registered computerised practices two geographical regions...
This study aimed to understand patient information needs and how best meet them in order improve rehabilitation provision aid disease self-management by exploring experiences of people who had recently completed a pulmonary programme community hospital setting.Qualitative research using focus groups was undertaken with 23 patients within the previous four months. The were tape-recorded contemporaneous notes made. tapes transcribed verbatim template analysis used develop themes.The key for...
Objectives Using strong structuration theory, we aimed to understand the adoption and implementation of an electronic clinical audit feedback tool support medicine optimisation for patients in primary care. Design This is a qualitative study informed by theory. The analysis was thematic, using template approach. An priori set thematic codes, based on developed from literature applied transcripts. coding then modified through successive readings data. Setting Clinical commissioning group...
Monitoring for potentially hazardous prescribing is increasingly important to improve medication safety. Healthcare information technology can be used achieve this aim, example by providing access data through surveillance of patients' electronic health records. The aim our study was examine the implementation and adoption an medicines optimisation system that intended facilitate clinical audit in primary care identifying patients at risk adverse drug event. We adopted a sociotechnical...
Background There is a need for greater understanding of the epidemiology primary care patient safety in order to generate solutions prevent future harm. Aim To estimate rate failures processing actions requested hospital discharge summaries, and determine factors associated with these failures. Design setting The authors undertook retrospective records review. study population was emergency admissions patients aged ≥75 years, drawn from 10 practices three areas England. Method One GP...
Objective To implement complex, PINCER (pharmacist led information technology intervention) prescribing indicators, on a national scale with general practice data to describe the impact of covid-19 pandemic safe prescribing. Design Population based, retrospective cohort study using federated analytics. Setting Electronic health record from 56.8 million NHS patients by use OpenSAFELY platform, approval National Health Service (NHS) England. Participants (aged 18-120 years) who were alive and...
Objectives: To estimate the costs of commonly used treatments for cutaneous warts, as well their health benefits and risk. create an economic decision model to evaluate cost-effectiveness these treatments, and, a result, assess whether randomised controlled trial (RCT) would be feasible cost-effective. Data sources: Focus groups, structured interviews and observation practice. Postal survey sent to 723 patients. A recently updated Cochrane systematic review published cost...
Discharge summaries are essential for communicating patient information from secondary care to general practice on hospital discharge. Although there has been extensive research into their design and completion in care, very little is known about primary processing of these documents.To explore what staff think the factors associated with failure respond actions requested discharge practices do mitigate this.Semi-structured interviews were undertaken three geographical regions...
Major gaps remain in our understanding of primary care patient safety. We describe a toolkit for measuring safety family practices.Six tools were used 46 practices. These as follows: National Health Service Education Scotland Trigger Tool, Medicines Reconciliation Primary Care Safequest, Prescribing Safety Indicators, Patient Reported Experiences and Outcomes Care, Concise Safe Systems Checklist.Primary Safequest showed that most practices had well-developed climate. However, the trigger...
Abstract Objective To describe the impact of COVID-19 pandemic on safe prescribing, using PINCER prescribing indicators; to implement complex indicators at national scale GP data. Design Population based cohort study, with approval NHS England OpenSAFELY platform. Setting Electronic health record data from 56.8 million patients’ general practice records. Participants All patients registered a TPP or EMIS computer systems and recorded as risk least one potentially hazardous indicator between...
Background We previously reported on a randomised trial demonstrating the effectiveness and cost-effectiveness of pharmacist-led information technology intervention (PINCER). sought to investigate whether PINCER was effective in reducing hazardous prescribing when rolled out at scale UK general practices. Methods findings used multiple interrupted time series design whereby successive groups practices received between September 2015 April 2017. 11 safety indicators identify potentially...