A5011992785- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Mycotoxins in Agriculture and Food
- Legionella and Acanthamoeba research
- Plant Pathogens and Fungal Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
University of Manchester
2022-2024
Manchester Academic Health Science Centre
2022
ABSTRACT Awareness that fungal coinfection complicates viral respiratory infections causing worse disease outcome has recently emerged. The environmental fungus Aspergillus fumigatus ( Af ) been reported as the main driver of in patients suffering from caused by Cytomegalovirus, Influenza or more SARS-CoV2. airway epithelium is first common point contact between inhaled pathogens and host. Aberrant epithelial cell (AEC) responses against challenge have described susceptible to aspergillosis....
ABSTRACT Aspergillus fumigatus , an important pulmonary fungal pathogen causing several diseases collectively called aspergillosis, relies on asexual spores or conidia for initiating host infection. Here, we used a phylogenomic approach to compare proteins in the conidial surface of A. two closely related non-pathogenic species, fischeri and oerlinghausenensis cryptic lentulus . After identifying 62 uniquely expressed surface, deleted 42 genes encoding proteins. We found deletion 33 these...
, an important pulmonary fungal pathogen causing several diseases collectively called aspergillosis, relies on asexual spores (conidia) for initiating host infection. Here, we used a phylogenomic approach to compare proteins in the conidial surface of