- Genetic Mapping and Diversity in Plants and Animals
- Genetics and Plant Breeding
- Genetic diversity and population structure
- Wheat and Barley Genetics and Pathology
- Chromosomal and Genetic Variations
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Genetic and phenotypic traits in livestock
- Plant Disease Resistance and Genetics
- Plant Taxonomy and Phylogenetics
- Genomics and Phylogenetic Studies
- Crop Yield and Soil Fertility
- Plant Virus Research Studies
- Bioenergy crop production and management
- Genetic and Environmental Crop Studies
- Plant Gene Expression Analysis
- Genetics, Bioinformatics, and Biomedical Research
- Agronomic Practices and Intercropping Systems
- Plant and soil sciences
- Plant Pathogens and Fungal Diseases
- CRISPR and Genetic Engineering
- Mycorrhizal Fungi and Plant Interactions
- Plant Genetic and Mutation Studies
- Plant Pathogens and Resistance
- Biofuel production and bioconversion
University of Wisconsin–Madison
2012-2021
University of Minnesota
1992-2019
Shanxi Normal University
2016-2019
University of California, Davis
2019
University of California, Riverside
1992-2019
Laboratory of Molecular Genetics
2007-2016
Madison Group (United States)
2016
Chinese Academy of Agricultural Sciences
2014
Biotechnology Research Institute
2014
Cornell University
2001-2014
There exists extraordinary morphological and genetic diversity among the maize landraces that have been developed by pre-Columbian cultivators. To explain this high level of in maize, several authors proposed were products multiple independent domestications from their wild relative (teosinte). We present phylogenetic analyses based on 264 individual plants, each genotyped at 99 microsatellites, challenge multiple-origins hypothesis. Instead, our results indicate all arose a single...
Association studies based on linkage disequilibrium (LD) can provide high resolution for identifying genes that may contribute to phenotypic variation. We report patterns of local and genome-wide LD in 102 maize inbred lines representing much the worldwide genetic diversity used breeding, address its implications association maize. In a survey six genes, we found intragenic generally declined rapidly with distance ( r 2 < 0.1 within 1500 bp), but rates decline were highly variable among...
Crop improvement and the dissection of complex genetic traits require germplasm diversity. Although this necessary phenotypic variability exists in diverse maize, most research is conducted using a small subset inbred lines. An association population 302 lines now available--a valuable tool that captures large proportion alleles cultivated maize. Provided appropriate statistical models correcting for structure are included, can be used analyses to provide high-resolution evaluation multiple...
Domestication promotes rapid phenotypic evolution through artificial selection. We investigated the genetic history by which wild grass teosinte (Zea mays ssp. parviglumis) was domesticated into modern maize (Z. mays). Analysis of single-nucleotide polymorphisms in 774 genes indicates that 2 to 4% these experienced The remaining retain evidence a population bottleneck associated with domestication. Candidate selected putative function plant growth are clustered near quantitative trait loci...
The cycloidea (cyc) and teosinte branched 1 (tb1) genes code for structurally related proteins implicated in the evolution of key morphological traits. However, biochemical function CYC TB1 remains to be demonstrated. To address this problem, we have analysed predicted secondary structure regions conserved between TB1, looked known function. One is form a non-canonical basic-Helix-Loop-Helix (bHLP) structure. This domain also found two rice DNA-binding proteins, PCF1 PCF2, where it has been...
Abstract Two quantitative trait loci (QTL) controlling differences in plant and inflorescence architecture between maize its progenitor (teosinte) were analyzed. Complementation tests indicate that one of these, which is on chromosome arm 1L, the locus for mutant teosinte branched1 (tb1). This QTL has effects sex number length internodes lateral branches inflorescences. strong phenotypic background but reduced background. The second QTL, 3L, affects same traits as 1L. We identify two...
It has long been suspected that maize is the product of an historical tetraploid event. Several observations support this possibility, including fact genome contains duplicated chromosomal segments with colinear gene arrangements. Some genes from these have sequenced. In study, we examine pattern sequence divergence among 14 pairs genes. We compare to patterns predicted by four models evolution genome—autotetraploidy, genomic allotetraploidy, segmental and multiple duplications. Our analyses...
We measured sequence diversity in 21 loci distributed along chromosome 1 of maize ( Zea mays ssp. L.). For each locus, we sequenced a common sample 25 individuals representing 16 exotic landraces and nine U.S. inbred lines. The data indicated that has an average one single nucleotide polymorphism (SNP) every 104 bp between two randomly sampled sequences, level higher than either humans or Drosophila melanogaster . A comparison genetic the landrace samples showed inbreds retained 77%...
Independent domestication of sorghum, rice, and maize involved convergent selection for large seeds, reduced disarticulation the mature inflorescence, daylength-insensitive flowering. These similar phenotypes are largely determined by a small number quantitative trait loci (QTLs) that correspond closely in three taxa. The correspondence these QTLs transcends 65 million years reproductive isolation. This finding supports models inheritance invoke relatively few genes, obviates difficulties...
Abstract Two hundred and sixty maize inbred lines, representative of the genetic diversity among essentially all public lines importance to temperate breeding many important tropical subtropical were assayed for polymorphism at 94 microsatellite loci. The 2039 alleles identified served as raw data estimating structure diversity. A model-based clustering analysis placed in five clusters that correspond major groups plus a set showing evidence mixed origins. “phylogenetic” tree was constructed...
Abstract Molecular marker loci were used to investigate the inheritance of morphological traits that distinguish maize (Zea mays ssp. mays) from a closely related wild relative, teosinte (Z. mexicana). Regression and interval mapping analyses gave largely congruent results concerning numbers controlling magnitudes their effects; however, tended give larger estimates for effects trait loci. This tendency was exaggerated non-normally distributed. Variation most inflorescence is controlled by...
The last two decades have seen important advances in our knowledge of maize domestication, thanks part to the contributions genetic data. Genetic studies provided firm evidence that was domesticated from Balsas teosinte ( Zea mays subspecies parviglumis ), a wild relative is endemic mid- lowland regions southwestern Mexico. An interesting paradox remains, however: Maize cultivars are most closely related found mainly Mexican highlands where does not grow. data thus point primary diffusion...