- Physical Activity and Health
- Obesity, Physical Activity, Diet
- Mobile Health and mHealth Applications
- Musculoskeletal pain and rehabilitation
- Sperm and Testicular Function
- Urban Transport and Accessibility
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Monoclonal and Polyclonal Antibodies Research
- Behavioral Health and Interventions
- Immune Cell Function and Interaction
- Cardiovascular and exercise physiology
- Xenotransplantation and immune response
- Balance, Gait, and Falls Prevention
- Nutrition and Health in Aging
- Blood groups and transfusion
- Digital Mental Health Interventions
- Urologic and reproductive health conditions
- Physical Education and Training Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Therapeutic Uses of Natural Elements
- Health and Wellbeing Research
- Cell Adhesion Molecules Research
- Injury Epidemiology and Prevention
- Health disparities and outcomes
The University of Tokyo
2007-2025
University of Tokyo Health Sciences
2022-2024
Harvard University
2014-2019
Kyoto University
2018
Brigham and Women's Hospital
2014-2017
National Institute of Infectious Diseases
2007-2017
National Institute of Biomedical Innovation, Health and Nutrition
2017
National Institute of Health Sciences
2017
National Institute on Aging
2015-2016
National Institutes of Health
2015-2016
A goal of 10 000 steps/d is commonly believed by the public to be necessary for health, but this number has limited scientific basis. Additionally, it unknown whether greater stepping intensity associated with health benefits, independent steps taken per day.To examine associations day and all-cause mortality.This prospective cohort study included 18 289 US women from Women's Health Study who agreed participate wearing an accelerometer during waking hours 7 days between 2011 2015. total 17...
Background: Recent research has revealed the importance of neighborhood environment as a determinant physical activity. However, evidence among elderly adults is limited. This study examined association between perceived and walking for specific purposes Japanese adults.Methods: population-based, cross-sectional enrolled 1921 participants (age: 65–74 years, men: 51.9%). Neighborhood (International Physical Activity Questionnaire Environmental Module) (ie, transportation or recreation) were...
Background Few data exist on the association between strength training and mortality rates. We sought to examine all‐cause, cardiovascular disease, cancer mortality. Methods Results Beginning in 2001 2005, 28 879 women throughout United States (average baseline age, 62.2 years) from Women's Health Study who were free of diabetes mellitus, reported their physical activities, including training. During follow‐up (average, 12.0 through 2015, investigators documented 3055 deaths (411 disease 748...
Background: Smartphones have great potential for monitoring physical activity. Although a previous laboratory-based study reported that smartphone apps were accurate tracking step counts, little evidence on their accuracy in free-living conditions currently exists. Objective: We aimed to investigate the of counts measured using iPhone real world. Methods: recruited convenience sample 54 adults (mean age 31 [SD 10] years) who owned an and analyzed data collected 2016 2017. Step count was...
Social participation has been suggested as a means to prevent depressive symptoms. However, it remains unclear whether one-time boost suffices or needs be sustained over time for long-term prevention. We estimated the impacts of alternative hypothetical interventions in social on subsequent symptoms among older adults.Data were from nationwide prospective cohort study Japanese adults ≥65 years age (n = 32,748). analyzed (1) baseline exposure 2010 (approximating intervention) and (2)...
We aimed to evaluate the effectiveness of a community-wide campaign (CWC) for promoting physical activity in middle-aged and elderly people. A cluster randomized controlled trial (RCT) with community as unit randomization was performed using population-based random-sampled evaluation by self-administered questionnaires city Unnan, Shimane Prefecture, Japan. The sample included 6000 residents aged 40 79 years. randomly allocated nine communities intervention group three control group. CWC...
Evidence from a limited number of short-term trials indicates the difficulty in achieving population-level improvements physical activity (PA) through community-wide interventions (CWIs). We sought to evaluate effectiveness 5-year CWI for promoting PA middle-aged and older adults using cluster randomized design.We 12 communities Unnan, Japan, either intervention (9) or control (3). Additionally, were randomly allocated three subgroups by different types promoted. Randomly sampled residents...
This study aimed to examine how accelerometer-assessed physical activity accumulation patterns (e.g., is performed daily or only 1 2 d·wk accrued in bouts) may affect the association with mortality.Adults (N = 3438), age 40 yr and older, who wore an accelerometer (ActiGraph 7164), were drawn from longitudinal follow-up of National Health Nutritional Examination Survey (2003-2006), a population-based survey United States. Accelerometer-assessed moderate-to-vigorous (MVPA) was described by...
Physical inactivity during the coronavirus disease 2019 (COVID-19) pandemic may have hindered development of fundamental movement skills in preschoolers. This serial cross-sectional study compared by age group before and COVID-19 (2019-2020), among Japanese preschoolers aged 3-5 years.Of 22 preschools within Unnan City, Shimane Prefecture, Japan, 21 (95.5%) 17 (77.3%) participated 2020 surveys, respectively. We analyzed 608 517 both surveys. Fundamental were objectively assessed with a 25 m...
In Japan, the incidence of kidney stones has increased markedly in recent decades. Major causes remain unclear, and limited data are available on relationship between overweight/obesity stones. We therefore evaluated body mass index (BMI) Japanese men.Of workers at a gas company, 5984 males aged 20-40 years underwent medical examination 1985 (baseline). This study includes 4074 men, who were free baseline second performed April 2004 March 2005. BMI was calculated from measured height weight...
In Brief Physical activity has multiple health benefits but may also increase the risk of developing musculoskeletal pain (MSP). However, relationship between physical and MSP not been well characterized. This study examined dose–response sports among adolescents. Two school-based serial surveys were conducted 1 year apart in adolescents aged 12 to 18 years Unnan, Japan. Self-administered questionnaires completed by 2403 students. Associations time spent organized analyzed cross-sectionally...
As older adults in an early stage (prefrailty) of frailty may return to a healthy state, it is necessary examine the prevention prefrailty. In this context, number and types social participation activities associated with physical prefrailty community-dwelling have remained relatively unexplored. This cross-sectional study investigates issue by analyzing 616 participants living Okinoshima, Shimane, rural area Japan, 2019. Frailty was assessed using 5-item phenotype (unintentional weight...
Leptin, which is the product of obese gene, believed to play important roles in pubertal development and reproductive function females. In a study using adult male rats, it was found that leptin stimulated secretion gonadotropin from pituitary dose-related manner. However, there has been no such female rats.To investigate effects on production LH FSH primary cultured cells.In this study, we determined body weight, serum concentration estradiol (E(2)) Wistar rats at 3, 5, 6, 7, 9 11 weeks...
Background: Both little and excessive physical activity (PA) may relate to chronic musculoskeletal pain. The primary objective of this study was characterize the relationship PA levels with low back pain (CLBP) knee (CKP).Methods: We evaluated 4559 adults aged 40–79 years in a community-based cross-sectional survey conducted 2009 Shimane, Japan. used self-administered questionnaires assess sociodemographics health status: assessed by International Physical Activity Questionnaire, CLBP CKP...
In recent years, it has become feasible to use devices for assessing physical activity and sedentary behavior among large numbers of participants in epidemiologic studies, allowing more precise assessments these behaviors quantification their associations with health outcomes. Between 2011 2015, the Women's Health Study (WHS) used Actigraph GT3X+ device measure over 7 days, during waking hours, 17,708 women (mean age, 72 years) living throughout United States. Devices were sent returned by...
To examine whether the chronicity and intensity of low back pain (LBP) or knee (KP) was associated with occurrence falls among a community-dwelling older population.This community-based 3-year prospective cohort study. In 2009, baseline questionnaires were mailed to 3080 randomly selected residents aged 60-79 years; 2534 (82.3%) responded survey, 1- follow-up surveys subsequently them. The data for 1890 respondents who had no in past year at analyzed. Associations between status (chronicity,...
Digital mental health interventions are being used more than ever for the prevention and treatment of psychological problems. Optimizing implementation aspects digital is essential to deliver program populations in need, but there a lack validated outcome measures interventions.The primary aim this study develop scales different levels stakeholders involved process: users, providers, managers or policy makers. The secondary validate developed scale users.We English Japanese versions (iOSDMH)...