A5100693345- Anesthesia and Pain Management
- Ovarian cancer diagnosis and treatment
- Anesthesia and Sedative Agents
- Inflammatory mediators and NSAID effects
- Cancer, Stress, Anesthesia, and Immune Response
- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Nausea and vomiting management
- Pain Mechanisms and Treatments
- Acupuncture Treatment Research Studies
- Respiratory Support and Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Airway Management and Intubation Techniques
- Inflammatory Biomarkers in Disease Prognosis
- Pain Management and Opioid Use
- Traumatic Brain Injury and Neurovascular Disturbances
- Congenital Diaphragmatic Hernia Studies
- Ultrasound in Clinical Applications
- Optical Imaging and Spectroscopy Techniques
- Pain Management and Placebo Effect
- Ion Transport and Channel Regulation
- Cancer Risks and Factors
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Endometrial and Cervical Cancer Treatments
University of Science and Technology of China
2019-2025
Anhui Provincial Hospital
2009-2021
Diagnostics for the Real World (United States)
2021
Anhui Medical University
2010-2018
Shandong University
2014
Guangdong Institute for Drug Control
2014
Objective: To evaluate the effects of different ciprofol doses on hemodynamics in patients undergoing cardiac surgery. Methods: 209 were randomly divided into four groups: 0.2 mg/kg etomidate group (group E, n = 50), mg/kg, 0.3mg/kg, 0.4mg/kg A, 53, B, 51, C, 54). Mean arterial pressure (MAP), heart rate (HR), output (CO), stroke volume (SV), systemic vascular resistance (SVR), and bispectral index recorded at following time points: 5 minutes after entering operating room (T 0 ); before...
Background: Goal-directed therapy confers a strong prognosis in patients undergoing major cardiac or noncardiac surgery. The present study investigated whether intraoperative goal-directed fluid restriction (GDFR) using stroke volume variation (SVV) and index could improve oxygenation postoperative outcome one-lung ventilation (OLV).
Background . Comparing the effect of two different κ ‐receptor agonists, nalbuphine and oxycodone, regular morphine in patients for prophylactic analgesia acute pain after daytime laparoscopic cholecystectomy. Methods One hundred twenty‐four undergoing cholecystectomy were randomly allocated to receive (group N), oxycodone O), M). The three groups all given intravenous injection (iv.) 0.15 mg/kg before incision 0.05 at end pneumoperitoneum. Visual Analogue Scale (VAS) scores (incision,...
Abstract Objectives To assess the prevalence of postoperative pulmonary complications (PPCs), perioperative factors associated with PPCs, and association PPCs outcomes in ovarian cancer patients undergoing cytoreductive surgery. Methods A retrospective analysis was conducted on who underwent surgery our hospital, between September 2017 January 2021, patient medical records were reviewed to collect relevant clinical information. Univariable multivariable analyses used identify significant...
The present study evaluated whether flurbiprofen increased the naturally circulating dendritic cells (DCs) subsets in patients with esophageal squamous cell carcinoma (ESCC) undergoing resection. Compared to healthy donors (n=20), significantly depressed percentages of plasmacytoid DCs (pDCs), CD1c+ myeloid (mDCs), and CD141+ mDCs among ESCC (n=60) were confirmed. Flurbiprofen was administered before skin incision at end operation group F (n=30), as well placebo C (n=30). postoperative...
The aim of the present study was to assess effect electro-acupuncture (EA) stimulation on remifentanil-induced postoperative hyperalgesia (RIPH) and possible involvement spinal microglia suppression. A model RIPH established using adult male Sprague-Dawley rats by administration remifentanil at 0.08 mg/kg intravenously for 60 min. Huantiao Yanglingquan acupoints were stimulated continuously EA (2 Hz, ~1 mA) 90 min from before paw incision end administration. Sham in sham group. Paw...
Abstract Objectives Several studies have shown that propofol administration during surgery effectively attenuates remifentanil-induced hyperalgesia (RIH). Ciprofol, a novel intravenous sedative agent analogous to propofol, has not yet been proven efficacious in alleviating RIH. The present study aimed investigate the effect of ciprofol on RIH and possible mechanisms involved. Methods model was established by an infusion remifentanil (1 μg·kg−1·min−1) 60 min rats with incisional pain....
Intraoperative hypotension (IOH) prediction using Mean Arterial Pressure (MAP) is a critical research area with significant implications for patient outcomes during surgery. However, existing approaches predominantly employ static modeling paradigms that overlook the dynamic nature of physiological signals. In this paper, we introduce novel Hybrid Multi-Factor (HMF) framework reformulates IOH as blood pressure forecasting task. Our leverages Transformer encoder, specifically designed to...
Objective To evaluate the effects of endobronchial blocker (EBB) in video-assisted thoracoscopy surgery (VATS).Methods 100 patients undergoing VATS were randomly divided into 2 groups (n=50):EBB group (group E) and double-lumen tube (DLT)group D).The intubation positioning time,pulmonary collapse time,the frequence DLT or bronchial blockage's shifting,effects one-lung ventilation (OLV),airway pressure impairments lower respiratory tract recorded.Results There no significant differences time...
The present study aimed to evaluate the postoperative complications and impact of an enhanced recovery programme in patients who underwent primary surgery (including extensive upper abdominal surgery) for epithelial ovarian carcinoma (EOC). All with stage I‑IV were identified, evaluated graded according Clavien‑Dindo classification. Of 161 patients, 46 (28.57%) surgical staging, 27 (16.77%) standard cytoreduction, 12 (7.45%) en bloc debulking 76 (47.20%) extraradical debulking. A total 157...
Cancer pain is an important factor affecting life quality of patients especially in the advanced stage and relieving one fundamental strategies for cancer treatment. Opioids such as morphine are most widely used clinics. However, they have been reported to be associated with occurrence development several types cancer. Thus, search opioid that has analgesic effect can retard progress simultaneously critical management. In this study, we first examined expression μ κ (MOR KOR) cell lines...
Objective To investigate the effect of flurbiprofen axetil on perioperative plasma levels prostaglandin E2 (PGE2) and β-endorphine (β-EP) in patients after remifentanil-based anesthesia.Methods Sixty ASA Ⅱ both sexes,aged 40-64 yr,weighing 50-75 kg,undergoing resection esophageal cancer,were randomly divided into 3 groups (n =20 each):intralipid group (group A),flurbiprofen pretreatment + postoperative analgesia with B) C).Anesthesia was induced propofol,remifentanil rocuronium maintained...
Abstract Background and Objectives Nonsteroidal anti‐inflammatory drugs (NSAIDs) have an response, but it remains unclear whether the perioperative use of flurbiprofen axetil can influence postoperative tumor recurrence survival in esophageal carcinoma. We aimed to explore effect intravenous on recurrence‐free (RFS) overall (OS) patients with carcinoma who underwent thoracoscopic esophagectomy. Methods This retrospective study included surgery for between December 2009 May 2015 at Department...
Abstract Objective We sought to evaluate the postoperative control of pain and recovery in patients with ovarian cancer who underwent cytoreductive surgery by adding dexmedetomidine ropivacaine bilateral dual-transversus abdominis plane (Bd-TAP) blocks. Methods enrolled 90 an American Society Anesthesiologists physical status I III undergoing open abdominal this study. Patients were randomized assigned into three groups (TAP-R, TAP-DR, or CON) 30 participants each. All received standardized...
Background The proportion of obese people is rising. Obesity influences the normal physiological function, causing lots problems in anesthesia, especially during one-lung ventilation(OLV). Objective To reduce effect ventilation on prognosis and decrease incidence perioperative respiratory complications patients. Content To explore strategies OLV for obesity patients period, including choices modes, protective strategy, hypercapnia, alveolar recruitment strategy oxygen...