A5068520248- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Photoacoustic and Ultrasonic Imaging
- Cardiac Valve Diseases and Treatments
- Angiogenesis and VEGF in Cancer
- Lipoproteins and Cardiovascular Health
- Atherosclerosis and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Acute Ischemic Stroke Management
- Mechanical Circulatory Support Devices
- Peripheral Artery Disease Management
- Retinal Imaging and Analysis
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Pressure and Hypertension Studies
- Cardiac electrophysiology and arrhythmias
- Ultrasound Imaging and Elastography
- Vascular Procedures and Complications
- Advanced MRI Techniques and Applications
- Pulmonary Hypertension Research and Treatments
- Cardiac and Coronary Surgery Techniques
Rijnstate Hospital
2022-2025
Radboud University Nijmegen
2021-2023
Radboud University Medical Center
2021-2023
University Medical Center
2022
Erasmus University Rotterdam
2011-2014
Erasmus MC
2011-2014
Rotterdam University of Applied Sciences
2013
National School of Public Health
2013
Hospices Civils de Lyon
2012
Hôpital Louis Pradel
2012
Carotid contrast-enhanced ultrasound (CEUS) was recently proposed for the evaluation of large-vessel vasculitides (LVV), particularly to assess vascularization within vessel wall. The aim this pilot study evaluate potential carotid colour Doppler (CDUS) and CEUS in patients with LVV.This prospective included seven (mean age 48 ± 14 years, all females) established LVV (Takayasu arteritis or giant cell arteritis). All underwent CDUS (14 arteries). Intima-media thickness, lumen diameter,...
Background A coronary function test (CFT) is the recommended diagnostic to identify vasomotor dysfunction as a cause of symptoms in patients with angina and nonobstructive arteries (ANOCA). Acetylcholine commonly used pharmacological agent for spasm provocation. We aimed investigate an association between severity provocative acetylcholine dose. Methods Results included ANOCA undergoing clinically indicated CFT from Netherlands Registry Invasive Coronary Vasomotor Function Testing: NL‐CFT....
Patients with diabetes mellitus (DM) are at severely increased risk of developing atherosclerosis. Intraplaque neovascularization (IPN) and plaque ulceration markers the vulnerable plaque, which is an rupture may lead to cardiovascular events. The aim this study was assess prevalence subclinical carotid atherosclerosis, intraplaque (IPN), in asymptomatic patients DM. A total 51 DM underwent standard ultrasound conjunction contrast-enhanced (CEUS) IPN, ulceration. Subclinical atherosclerosis...
Introduction: Invasive coronary function testing (CFT) has become the recommended diagnostic tool to assess various endotypes of vasomotor dysfunction in patients with angina and no obstructive artery disease (ANOCA), which implications for therapy prognosis. Although expanding performance CFT is leading increased knowledge dysfunction, little known about sex-related differences results comprehensive CFT. Methods: We conducted a prospective study all consecutive ANOCA that underwent...
<b>Purpose:</b> Intraplaque neovascularization (IPN) is an increasingly studied marker of the vulnerable atherosclerotic plaque, and contrast-enhanced ultrasound (CEUS) in vivo imaging technique for assessment IPN. The purpose this study was to test novel quantification methods detection carotid IPN using CEUS. <b>Materials Methods:</b> 25 patients with established atherosclerosis underwent bilateral CEUS a Philips iU-22 system L9 – 3 transducer. Visual scoring performed 3-point score....
Background. If surgical revascularization is not feasible, high-risk PCI a viable option for patients with complex coronary artery disease. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) provides hemodynamic support in high risk periprocedural cardiogenic shock. Objective. This study aims to provide data about short-term outcomes of elective ECMO support. Methods. A retrospective single-center registry was performed on receiving VA-ECMO The outcome defined as the incidence major...
In standard B-mode ultrasound (BMUS), segmentation of the lumen atherosclerotic carotid arteries and studying geometry over time are difficult owing to irregular shapes, noise, artifacts, echolucent plaques. Contrast enhanced (CEUS) improves visualization, but remains challenging varying intensities, CEUS-specific artifacts lack tissue visualization. To overcome these challenges, we propose a novel method using simultaneously acquired BMUS&CEUS image sequences. Initially, estimates nonrigid...
Intraplaque neovascularization (IPN) has been linked with progressive atherosclerotic disease and plaque instability in several studies. Quantification of IPN may allow early detection vulnerable plaques. A dedicated motion compensation method normalized-cross-correlation (NCC) block matching combined multidimensional (2D+time) dynamic programming (MDP) was developed for quantification small plaques (<30% diameter stenosis). The compared to NCC without MDP (forward tracking (FT)) showed...
The sensitivity of standard carotid ultrasound and colour Doppler for the detection subclinical atherosclerotic plaques is suboptimal. aim this study to assess whether contrast-enhanced (CEUS) added improves atherosclerosis. Carotid intima–media thickness (CIMT) measurement, including imaging, CEUS were performed in 100 asymptomatic patients with one or more risk factors was using intravenous administration SonoVue™ contrast agent (Bracco S.p.A., Milan, Italy). CIMT, ultrasound, Doppler,...
Intraplaque neovascularization (IPN) is an important biomarker of atherosclerotic plaque vulnerability. As IPN can be detected by contrast enhanced ultrasound (CEUS), imaging-biomarkers derived from CEUS may allow early prediction To select the best quantitative for vulnerability, a systematic analysis with existing and new algorithms necessary. Currently available commercial quantification tools are not applicable carotid due to substantial motion artery, artifacts, intermittent perfusion...
An association between atherosclerosis and coronary vasospasm has previously been suggested. However, to date, no conclusive data on the whole spectrum of these disorders have published.This study aimed define specific morphological features in patients with angina obstructive artery disease (ANOCA) due vasospasm.From February 2019 January 2020, we enrolled 75 referred our laboratory for a function test (CFT) ANOCA suspected vasomotor dysfunction. The CFT consisted an acetylcholine...