Abstract As one of the most promising fluorescent nanomaterials, carbon dots (CDs) are extensively studied. Nevertheless, one‐pot synthesis methods for CDs with both dual emission aggregation‐induced (AIE) and room‐temperature phosphorescence (RTP) could lead to significant breakthrough in extensive application fields. Herein, a new class (E‐CCDs) reversible luminescence (blue dissolved fluorescence red AIE) RTP behavior is obtained an eco‐friendly, low‐cost solvothermal method. E‐CCDs...

Aromatic amide-derived phosphanes (Aphos) are hemilabile P,O-coordinating ligands, which, when combined with a Pd precursor, yield promising precatalyst system for Suzuki-Miyaura cross-coupling reactions. A focused library of Aphos ligands has been constructed structural optimization, the target improving catalytic efficacy. By using microwave irradiation at accurately regulated temperature, an expeditious and reproducible one-pot synthesis screening protocol was designed experimentally...

Amphidinolide Y, a 17-membered cytotoxic macrolide isolated from marine dinoflagellates, has been synthesized via ring-closing metathesis to assemble the congested trisubstituted (E)-double bond. The seco precursor was prepared readily available chiral synthons with tetrahydrofuran ring formed 5-endo epoxide ring-opening cyclization. It found that C6-keto substrate showed higher reactivity toward Grubbs' second generation catalyst while Schrock's Mo completely inactive for formation of macrocycle.

A sequence of the Ugi four-component reaction (U-4CR) and microwave-assisted intramolecular Ullmann etherification has been established for efficient generation a dibenz[b,f][1,4]oxazepine scaffold. The U-4CR, using 2-aminophenols 2-bromobenzoic acids or 2-bromobenzaldehydes as inputs, was carried out in MeOH at 50–60 °C 2–3 days to form collection 22 linear products 46–90% yields. then used transform these acyclic U-4CR into cleft-shaped 6/7/6-fused tricyclic heterocycles. diaryl ether...

RCM+AD=T2: In the presence of C16-methylene group, regioselective ring-closing metathesis (RCM) formed (12E)-endocyclic double bond, which underwent Os-catalyzed asymmetric dihydroxylation (AD) to give desired 12,13-diol intermediate required for total synthesis amphidinolide T2 in 16 linear steps 8.0 % overall yield.

Cross combination: The olefinic CH bond in 1,1-diarylethenes selectively adds to the CC double of substituted styrenes a head-to-tail fashion under In(OTf)3 (OTf=triflate) catalysis (see scheme) while homo- and cyclodimerization reactions are suppressed. high chemo- regioselectivity this intermolecular hydroalkenylation originates from stability steric bulk diaryl-substituted tertiary carbocation intermediate. Detailed facts importance specialist readers published as ”Supporting...

Recycled fine aggregate (RFA) produced from concrete waste is commonly used in the construction industry; however, its use for structural members has not been extensively studied. Moreover, durability a drying-wetting cycle environment still needs to be examined. In this study, intrusion process of chloride under cycles experimentally characterized. Chloride penetration tests are carried out on with incorporation different RFA replacement rates and mineral admixtures (i.e., fly ash silica...

2-Aminophenols underwent the Ugi four-component reaction (U-4CR) with trans-cinnamic acids, aromatic aldehydes and isocyanides in MeOH (50 ˚C, 48 h) to give linear α-[N-(2-hydroxyphenyl)-substituted amido] carboxamides 54-80% yields. Treatment of 2-hydroxyphenyl moiety U-4CR products NaH PhNTf2 afforded corresponding aryl triflates (77-100%), which were subjected intramolecular Heck (IMHR) catalyzed by 3-5 mol% Pd(OAc)2-BINAP (MeCN, 180 30-60 min) under microwave heating furnish...

Abstract The Wittig reactions of three stabilized phosphorus ylides with aldehydes in water were investigated. Most the olefination completed within 5–60 min refluxing presence 1.2 M LiCl to afford olefin products 65–98% yields. It was found that faster than those carried out organic solvents.

Abstract One‐pot Wittig reactions of ethyl bromoacetate and bromoacetonitrile with aldehydes in the presence PPh3 LiOH water were investigated. Most olefination completed within 5–120 min refluxing containing 1.2 M LiCl to afford olefin products 71–97% yields 100:0–55:45 ratios E:Z isomers.

Amphidinolide X, a 16-membered cytotoxic macro­diolide, and its 12Z-isomer have been synthesized via ring-closing metathesis (RCM) for assembling the C12-C13 trisubstituted double bond. A 29:71 E/Z mixture was obtained from seco substrate appended with bulky C8-ODPS group in 50-65% combined yields by using 20 mol% of second-generation Grubbs initiator corresponding indenylidene ruthenium complex. X exhibit similar cytotoxicity (IC50: 7.6-13.9 µg/mL) against A549, KB, HL60 cell lines.

A ring-closing metathesis (RCM) approach was envisioned for installing the <i>E</i> double bond at C9 and C10 positions of divergolide A, isolated from a mangrove endophyte. Accordingly, C10–C15 diene diol fragment amido hydroquinone core with requisite functionalities stereochemistry have been synthesized by using norephedrine-based <i>syn</i>-selective glycolate aldol <i>anti</i>-selective reactions, respectively. CuI-catalyzed amidation employed to access anilide intermediate, which...

Abstract The Wittig reactions of three semistabilized phosphorus ylides generated in situ from the corresponding phosphonium salts with aldehydes water without any organic cosolvent were investigated. Most olefination completed within between 5 min and 4.5 h refluxing containing 1.5 equiv LiOH 1.4 M LiCl to afford products 65–100% yields. E∶Z selectivity depended not only on substituent attached benzene ring but also bound aromatic aldehydes. promotes aqueous suppresses decomposition ylide or salt.

Buckwheat is an important minor grain crop with medicinal and edible functions. The accurate judgment of buckwheat maturity beneficial to reduce harvest losses improve yield. With the rapid development unmanned aerial vehicle (UAV) technology, it has been widely used predict agricultural products. This paper proposed a method using recursive feature elimination cross-validation (RFECV) combined multiple regression models in UAV-RGB images. images were captured experimental field Shanxi...