A5014150237- Fibroblast Growth Factor Research
- Telomeres, Telomerase, and Senescence
- Electrohydrodynamics and Fluid Dynamics
- Plasma Diagnostics and Applications
- Advanced Vision and Imaging
- Image Processing Techniques and Applications
- Spectroscopy and Laser Applications
- Spine and Intervertebral Disc Pathology
- Bone fractures and treatments
- Orthopaedic implants and arthroplasty
- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Mesenchymal stem cell research
- Robotic Path Planning Algorithms
- Particle accelerators and beam dynamics
- Advanced Fiber Optic Sensors
- Genetics, Aging, and Longevity in Model Organisms
- Cancer-related molecular mechanisms research
- Magnesium Alloys: Properties and Applications
- Musculoskeletal pain and rehabilitation
- Advanced Image Processing Techniques
- Image Enhancement Techniques
- RNA modifications and cancer
- Corrosion Behavior and Inhibition
- Robotics and Sensor-Based Localization
XinHua Hospital
2016-2025
Zhengzhou University
2018-2025
Xiangtan University
2024
Shanghai Jiao Tong University
2023-2024
Xi'an Jiaotong University
2023-2024
First Affiliated Hospital of Xi'an Jiaotong University
2023-2024
Columbia University
2024
Augusta University
2024
Xi’an University of Posts and Telecommunications
2023-2024
Zhejiang University
2021-2023
The commercial implementation of aqueous Zn-ion batteries is being impeded by the rampant dendrite growth and exacerbated side reactions on Zn metal anodes. Herein, a 60 nm artificial protective layer with spatial dielectric–metallic gradient composition (denoted as GZH) developed via HfO2 cosputtering. In this design, top high permittivity low electronic conductivity effectively suppresses hydrogen evolution. intermediate Zn-rich oxide region promotes dendrite-free deposition reinforces...
N6-methyladenosine (m6A) is required for differentiation of human bone marrow mesenchymal stem cells (hBMSCs). However, its intrinsic mechanisms are largely unknown. To identify the possible role m6A binding protein YTHDF1 in hBMSCs osteogenesis vivo, we constructed Ythdf1 KO mice and showed that depletion would result decreased mass vivo. Both deletion mouse BMSCs shRNA-mediated knockdown prevented osteogenic vitro. Using methylated RNA immunoprecipitation (Me-RIP) sequencing...
Modulation technology is the necessary means for generating periodic acoustic waves in photoacoustic gas detection, primarily including intensity modulation and wavelength modulation. In multi-gas when multiple lasers employ same technique, current technologies include time-division multiplexing (TDM) measurements at different times frequency-division (FDM) simultaneous measurements; techniques, only available TDM with conducted times, whether measurement can be achieved has not yet been...
ABSTRACT Objective Coronal malalignment is a common feature of adult spinal deformity, and accurate classification essential for diagnosis treatment planning. However, variations in interpretation among clinicians can impact consistency. By assessing the reliability applicability these systems across different medical experts, this study seeks to establish standardized approach enhance clinical outcomes. This aimed evaluate inter‐ intra‐observer agreement two coronal deformity patients, as...
Background Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by systemic inflammation and immune dysregulation, leading to higher risk of all-cause mortality. The Pan-Immune Inflammation Value (PIV), novel biomarker capturing immune-inflammatory activity, has shown prognostic value in various diseases. However, its role predicting outcomes RA patients remains largely unexplored. Objectives This study aimed evaluate the association between PIV mortality patients, investigate...
Background: It has been reported that loss of PCBP2 led to increased reactive oxygen species (ROS) production and accelerated cell aging. Knockdown in HCT116 cells leads significant downregulation fibroblast growth factor 2 (FGF2). Here, we tried elucidate the intrinsic factors potential mechanisms bone marrow mesenchymal stromal (BMSCs) aging from interactions among PCBP2, ROS, FGF2. Methods: Unlabeled quantitative proteomics were performed show differentially expressed proteins replicative...
The process of intervertebral disc degeneration (IVDD) is complex, and its mechanism considered multifactorial. Apoptosis oxidative stressed nucleus pulposus cells (NPCs) should be a fundamental element in the pathogenesis IVDD. In our pilot study, we found that expression MAT2A decreased, METTL16 increased degenerative tissues. Previous studies have shown balance splicing, maturation, degradation pre-mRNA regulated by m6A modification. current aimed to figure out whether this was involved...
Tibial plateau fractures are of great challenge to treat with open reduction and internal fixation, because vary from simple complex, little or extensive articular involvement. Hence, recognition comprehension the fracture features will help orthopedic surgeons understand injury mechanism better manage these by planning optimal surgical procedures. This study aimed evaluate morphological characteristics tibial based on Schatzker classification.A total 186 patients 188 2010 2014 in our...
Lateral column tibial plateau fracture fixation with a locking screw plate has higher mechanical stability than other methods. The objectives of the present study were to introduce two newly designed anatomic plates for lateral and demonstrate their characteristics complexes under axial loads. Three different 3D finite element models bone created. Various forces (100, 500, 1000, 1500 N) applied simulate compressive load on an adult knee during daily life. equivalent maps displacement stress...
Abstract Bone health requires adequate bone mass, which is maintained by a critical balance between resorption and formation. In our study, we identified beraprost as pivotal regulator of formation resorption. The administration promoted differentiation mouse mesenchymal stem cells (M-BMSCs) through the PI3K–AKT pathway. co-culture, osteoblasts stimulated with inhibited osteoclastogenesis in rankl-dependent manner. mass p53 knockout mice remained stable, regardless beraprost, indicating that...
The introduction of cantilever-based fiber-optic microphones (FOMs) has proven to be effective in acoustic sensing. Further improvements cantilevers face two key constraints: the challenge achieving minimal sizes with sufficient reflective area and trade-off between sensitivity response bandwidth. Herein, we present a geometry optimization framework for FOM that addresses this issue. Employing drumstick-shaped housed within Fabry–Perot (F–P) interferometric structure, showcase heightened...
Magnetic mirror used as an efficient tool to confine plasma has been widely adopted in many different areas especially recent cusped field thrusters. In order check the influence of magnetic effect on distribution a thruster, three radii discharge channel (6 mm, 4 and 2 mm) thruster are investigated by using Particle-in-Cell Plus Monte Carlo (PIC-MCC) simulated method, under condition fixed axial length same operating parameters. It is found that cusps inside small radius cannot electrons...
The cusped field thruster uses several permanent ring magnets of alternating polarity to create a multistage cusp magnetic topology. It has demonstrated long lifetime because reduced plasma losses the discharge channel surface. However, high beam divergence problem not been solved in this type thruster. purpose technical note is describe plume control method reduce its angle. results show that intensity region and shape last separatrix have great influence on divergence.
Hepatocellular carcinoma (HCC) is known as the most common malignancy of hepatobiliary system with a continued increase in incidence but limited therapeutic options. Nanomedicine has provided promising strategy through engineered nanocarriers that are capable targeting agents specifically to tumor cells. In this research, two aptamer/peptide-modified lipid-based drug delivery systems (A54-PEG-SLN/OXA and A15-PEG-SLN/SAL) were developed sequential conquer specific hepatocellular carcinoma....
Inhibition of neuropeptide Y1 receptor stimulates osteogenesis in vitro and vivo. However, the underlying mechanisms involved these effects remain poorly understood. Here we identify deficiency on osteogenic differentiation human bone marrow stromal cells (BMSCs) by using genetic pharmacological regulation, to explore pathways mediating effects. In BMSCs, inhibition upregulates expression levels master transcriptional factor RUNX2. Mechanistically, increases intracellular cAMP, which via...