A5016740141- Cystic Fibrosis Research Advances
- Neonatal Respiratory Health Research
- Neonatal and Maternal Infections
- Tracheal and airway disorders
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Lung Cancer Treatments and Mutations
- Pulmonary Hypertension Research and Treatments
- Infections and bacterial resistance
- COVID-19 and Mental Health
- Lung Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Otolaryngology and Infectious Diseases
- Lung Cancer Research Studies
- Fungal Infections and Studies
- Neurosurgical Procedures and Complications
- Pediatric health and respiratory diseases
- Vascular Anomalies and Treatments
- Congenital Heart Disease Studies
- Cerebral Venous Sinus Thrombosis
- Transplantation: Methods and Outcomes
- Nail Diseases and Treatments
- Inhalation and Respiratory Drug Delivery
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intracerebral and Subarachnoid Hemorrhage Research
University of Calgary
2014-2024
University of Alberta
2023
Bridge University
2023
Alberta Health Services
2021-2023
Rockyview General Hospital
2017
Abstract Background Understanding of Long COVID has advanced through patient-led initiatives. However, research about barriers to accessing services is limited. This study aimed better understand the need for, access to, and quality of, services. We explored health needs experiences services, including ability address needs. Methods Our was informed by Levesque et al.’s (2013) “conceptual framework care.” used Interpretive Description, a qualitative approach partly at informing clinical...
Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant condition characterized by dermatologic lesions, pulmonary manifestations, and renal tumors. The arises from germline mutations in the folliculin (FLCN) gene. We present findings single largest family BHD cohort described to date. Primary objectives were characterize cystic lung changes on computed tomography (CT) chest scanning identify features that stratify patients at higher risk of pneumothorax. Secondary entailed description...
The aim of this qualitative study is to understand the need for, access to, and quality rehabilitation services for people living with Long COVID. Little known about experiences COVID accessing services. Therefore, we explored health concerns leading seek help address functional their participating in rehabilitation.
C-reactive protein (CRP) is a systemic marker of inflammation that correlates with disease status in cystic fibrosis (CF). The clinical utility CRP measurement to guide pulmonary exacerbation (PEx) treatment decisions remains uncertain.To determine whether monitoring during PEx can be used predict response. We hypothesized early changes response.We reviewed all events requiring hospitalization for intravenous (IV) antibiotics over 2 years at our institution. 83 met eligibility criteria....
<ns4:p>Pulmonary exacerbations are common events in cystic fibrosis and have a profound impact on quality of life, morbidity, mortality. Pulmonary exacerbation outcomes remain poor significant proportion patients fail to recover their baseline lung function despite receiving aggressive treatment with intravenous antibiotics. This focused review provides an update some the recent advances that taken place our understanding epidemiology, pathophysiology, diagnosis, management pulmonary as well...
Introduction: Only approximately 25% of stage iv non-small-cell lung cancer (nsclc) patients receive systemic therapy. For such patients, we examined factors affecting referral to a centre (cc) and medical oncology (mo), use Methods: Using the Glans–Look Lung Cancer database, completed chart review nsclc diagnosed in Southern Alberta during 2003–2006 2010–2011, comparing median overall survival (mos), referral, treatment two cohorts. Results: Of 922 560 94% 82% respectively were referred cc,...
Persistent airway infection is a hallmark feature of cystic fibrosis (CF). However, increasingly it has been observed that non-classical pathogens may transiently infect CF lower airways. Streptococcus pyogenes (Group A Streptococcus; (GAS)) an uncommon but potentially dangerous cause community-acquired pneumonia. Our aim was to determine the incidence, natural history, and clinical impact GAS infections in phenotypically genotypically characterize isolates.We retrospectively evaluated...
Group B Streptococcus (GBS) is a common commensal capable of causing severe invasive infections. Most GBS infections occur in neonates (often as pneumonia). can also cause infection adults with diabetes and other immunological impairments but rarely leads to pneumonia adults. has occasionally been found the sputum Cystic Fibrosis (CF) patients, an inherited condition known for progressive lung disease. However, epidemiology clinical significance CF are not understood. We retrospectively...
Idiopathic intracranial hypertension (IIH) is characterized by manifestations of raised pressure and predominantly affects overweight young women (1). Although common symptoms IIH include headaches, visual loss, pulsatile tinnitus, the clinical presentation highly variable There an emerging consensus that acetazolamide ameliorates effects (1,2). By stopping conversion water carbon dioxide to bicarbonate hydrogen ions with carbonic anhydrase inhibition, reduces cerebrospinal fluid secretion...
INTRODUCTION: CF is a genetic disease that can lead to significant morbidity. As the population increases and treatment regimens escalate in complexity, care costs are expected rise could put tremendous strain on health systems. Our aim was examine hospitalization of Canadian patients.METHODS: We analyzed annual hospital for patients 2014. Secondary objectives were cost differences1 Ratjen F, Doring G. Cystic fibrosis. Lancet. 2003;361(9358):681–689....
ABSTRACT Rationale There are approximately 35,000 people with Cystic Fibrosis (CF) in North America. This condition is characterized by impaired airway clearance resulting chronic infection and bronchiectasis. Current treatments include nebulized hypertonic saline Recombinant Human DNase, which may be limited bronchospasm cost, respectively. S-1226, a novel biophysical therapeutic agent combines carbon dioxide (CO 2 ) enriched air (a bronchodilator) perflubron (PFOB), synthetic surfactant)....
e19056 Background: Despite evidence for survival improvement, only about 25% of stage IV NSCLC patients receive ST. Factors affecting referral to CC, MO, and use ST are largely unknown. Methods: Stage in Southern Alberta were identified from the provincial cancer registry. Baseline characteristics, CC reasons referral/treatment decisions, collected electronic charts. Multivariate analyses performed compare median overall (mOS), treatment patterns two cohorts. Results: 925 2003-2006 261 2010...
Abstract Background: Understanding of Long COVID has advanced through patient-led initiatives. However, research about barriers to accessing services is limited. This study aimed better understand the need for, access to, and quality of, services. We explored health needs experiences services, including ability address needs. Methods: Our was informed by Levesque et al’s (2013) “conceptual framework care.” used Interpretive Description, a qualitative approach partly at informing clinical...