Bin Chen

ORCID: 0000-0003-1822-4486
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About
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Research Areas
  • Plant and animal studies
  • Plant and Fungal Species Descriptions
  • Plant Diversity and Evolution
  • Plant Parasitism and Resistance
  • Insect and Arachnid Ecology and Behavior
  • Phytochemistry and Biological Activities
  • Coleoptera: Cerambycidae studies
  • Forest Insect Ecology and Management
  • Fern and Epiphyte Biology
  • Ecology and Vegetation Dynamics Studies
  • Plant Pathogens and Fungal Diseases
  • Sesquiterpenes and Asteraceae Studies
  • Plant-based Medicinal Research
  • Coleoptera Taxonomy and Distribution
  • Biochemical and Structural Characterization
  • Plant Toxicity and Pharmacological Properties
  • Bioactive natural compounds
  • Medicinal Plants and Bioactive Compounds
  • Mycorrhizal Fungi and Plant Interactions
  • Traditional Chinese Medicine Analysis
  • Toxin Mechanisms and Immunotoxins
  • Phytochemical Studies and Bioactivities
  • Chemical Synthesis and Analysis
  • Soil Carbon and Nitrogen Dynamics
  • Fungal Biology and Applications

Yunnan Agricultural University
2020-2025

Nantong University
2024

Shanghai Chenshan Plant Science Research Center
2015-2024

Nanjing Agricultural University
2024

Guangdong Academy of Sciences
2024

Affiliated Hospital of Nantong University
2024

Second Affiliated Hospital of Nantong University
2024

Guangdong Medical College
2023

Chongqing Normal University
2014-2022

Guangdong Laboratory Animals Monitoring Institute
2022

Human activities have shaped large-scale distributions of many species, driving both range contractions and expansions. Species differ naturally in size, with small-range species concentrated particular geographic areas potentially deviating ecologically from widespread species. Hence, species' responses to human may be influenced by their sizes, but if how this happens are poorly understood. Here, we use a comprehensive distribution database modeling examine affected the extent which 9,701...

10.1073/pnas.1911851116 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2019-12-16

Abstract Aim The phylogenetic constraint hypothesis of flowering phenology states that closely related species flower at similar times the year. We test this for C hinese angiosperm flora and assess additional effects growth form, deciduousness, pollination mode fruit type. further examine whether conservatism tends to increase from tropical temperate latitudes. Location hina. Methods midpoint time 19,631 present in hina was compiled. signal evaluated whole country using B lomberg K ‐value...

10.1111/geb.12303 article EN Global Ecology and Biogeography 2015-04-01

Porcine reproductive and respiratory syndrome (PRRS) is an economically important disease of swine that caused by PRRS virus (PRRSV). In this study, we established a fluorescence assay for highly sensitive detection PRRSV through integration the reverse transcription–recombinase polymerase amplification (RT-RPA)-coupled Cas12a system with optical property single stranded DNA–fluorescently quenched (ssDNA-FQ) reporter. This technique can achieve isothermal visual in 25 min. particular,...

10.1021/acssynbio.1c00103 article EN cc-by-nc-nd ACS Synthetic Biology 2021-09-20

In long germ embryos, all body segments are specified simultaneously during the blastoderm stage. contrast, in short only anterior stage, leaving rest of plan to be later. The striking embryological differences between and segmentation imply fundamental patterning at molecular level. To gain insights into mechanisms insects, we have investigated role homologue Drosophila gap gene hunchback ( hb ) a insect Locusta migratoria manilensi by paternal RNA interference (RNAi). Phenotypes resulting...

10.1111/j.1440-169x.2006.00881.x article EN Development Growth & Differentiation 2006-09-01

ABSTRACT Various strains of entomopathogenic fungus Metarhizium flavoviride are potential insect control agents. However, there few systematic studies on their pathogenicity against larvae pests in the family Scarabaeidae. This study evaluates M. Ma130821 Metabolus flavescens Brenske feeding maize and tobacco, respectively, examines infection process aspects host immunological response. The present results showed that caused 76.67%–100.00% mortality within 18 days. When hyphal bodies...

10.1111/1748-5967.70019 article EN Entomological Research 2025-02-01

Cycloviolacin H4, a new macrocyclic miniprotein comprising 30 amino acid residues, was isolated from the underground parts of Australian native violet Viola hederaceae. Its sequence, cyclo-(CAESCVWIPCTVTALLGCSCSNNVCYNGIP), determined by nanospray tandem mass spectrometry and quantitative analysis. A knotted disulfide arrangement, which designated as cyclic cystine knot motif characteristic to all known cyclotides, is proposed for stabilizing molecular structure folding. The cyclotide...

10.1021/np050317i article EN Journal of Natural Products 2005-12-14

Abstract Aminolevulinic acid ( ALA )‐mediated protoporphyrin IX (Pp ) production is being explored for tumor fluorescence imaging and photodynamic therapy PDT ). As a prodrug, converted in heme biosynthesis pathway to Pp with fluorescent photosensitizing properties. To better understand the role of enzymes ‐mediated efficacy, we used lentiviral sh RNA silence expression porphobilinogen synthase PBGS ), deaminase PBGD ferrochelatase FECH SkBr3 human breast cancer cells. are first two...

10.1111/php.12454 article EN Photochemistry and Photobiology 2015-03-24

In this paper, Sedum xunvense is described as a new species from Zhejiang, Southeast China. morphologically similar to S. formosanum, but the latter differs in clustered and robust stems (vs. solitary, slender), green or slightly red smooth inflorescence rachises purple-red ribbed), thick succulent leaves thin), yellow anthers reddish-brown), erect follicles oblique), found dry habitats rock crevices damp ravines, rocks mossy thickets). A reconstructed ML phylogeny of Sedum, based on nrITS...

10.11646/phytotaxa.644.4.2 article EN Phytotaxa 2024-04-16

Bioassay-guided fractionation of EtOH extract the roots Scrophularia ningpoensis Hemsl. resulted in isolation three new iridoid glycosides, i.e., 6''-O-caffeoylharpagide (1), 6''-O-feruloylharpagide (2), and 6''-O-beta-glucopyranosylharpagoside (3), five aromatic 2-(3-hydroxy-4-methoxyphenyl)ethyl O-alpha-arabinopyranosyl-(1-->6)-O-alpha-rhamnopyranosyl-(1-->3)-O-beta-glucopyranoside (4), phenyl O-beta-xylopyranosyl-(1-->6)-O-beta-glucopyranoside (5), 3-methylphenyl (6), 6-O-cinnamoyl...

10.1002/cbdv.200890161 article EN Chemistry & Biodiversity 2008-09-01

Cycads represent one of the most ancestral living seed plants as well threatened plant groups in world. South China is a major center and potential origin Cycas , rapidly diversified lineage cycads. However, genomic-wide diversity remains poorly understood due to challenge generating genomic markers associated with their inherent large genomes. Here, we perform comprehensive conservation study based on restriction-site DNA sequencing (RADseq) data six representative species China....

10.3389/fgene.2021.717200 article EN cc-by Frontiers in Genetics 2021-08-30

Abstract Since the inception of genetic investigations into origin Dryopteris species belonging to D. subg. Erythrovariae in East Asia, around 20 taxa with hybrid ancestry have been identified. Among these species, some arisen from distant interspecific hybridization events. In this study, we describe and illustrate two newly discovered hybrids China: parabissetiana sp. nov., a triploid ×tiantangzhaiensis nothosp. diploid within Dryopteridaceae. Morphologically, exhibits similarities...

10.1002/tax.13116 article EN Taxon 2024-01-23

The Lingguizhugan decoction (LGZGD) is a promising traditional Chinese medicine for the treatment of gestational diabetes mellitus (GDM). However, its bioactive compounds and therapeutic mechanisms remain unknown. main chemical composition LGZGD was analyzed by high-performance liquid chromatography-mass spectrometry (HPLC-MS). Furthermore, underlying against GDM were elucidated through network pharmacology molecular docking. efficacy targets further confirmed via an in vitro model (high...

10.1002/bmc.6042 article EN Biomedical Chromatography 2024-11-12

Ultrasound-assisted extraction (UAE), using petroleum ether as the solvent, was systematically applied to extract main macamides and macaenes from Maca hypocotyls. Extraction yield related with four variables, including ratio of solution solid, temperature, time, power. On basis response surface methodology (RSM), optimal conditions were determined be solid 10:1 (mL/g), temperature 40 °C, time 30 min, power 200 W. Based on method UAE, total contents ten two cultivated in twenty different...

10.3390/molecules22122196 article EN cc-by Molecules 2017-12-10

Cyclotides are plant-derived macrocyclic peptides with potential applications in the pharmaceutical and agricultural industries. In addition to their presumed natural function as host-defence arising from insecticidal activity, other biological activities include antimicrobial, haemolytic, cytotoxic activities, but at present, only limited information is available on structural chemical features that important for these various activities. current study, we determined three-dimensional...

10.1071/ch10007 article EN Australian Journal of Chemistry 2010-01-01

Two α-L-ribo-configured bicyclic nucleic acid modifications, represented by analogues 12 and 13, which are epimeric at C3' C5' have been synthesized using a carbohydrate-based approach to build the core structure. An intramolecular L-proline-mediated aldol reaction was employed generate cis-configured ring junction of analogue represents rare application this venerable organocatalytic carbohydrate system. In case where trans-ring desired, an intermolecular diastereoselective Grignard...

10.1021/jo401166q article EN The Journal of Organic Chemistry 2013-08-12
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