A5056504933- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiac Health and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Disease Management Strategies
- Atrial Fibrillation Management and Outcomes
- COVID-19 and healthcare impacts
- Medication Adherence and Compliance
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Pharmaceutical Practices and Patient Outcomes
- COVID-19 Clinical Research Studies
- Emergency and Acute Care Studies
- Healthcare Policy and Management
- Healthcare Systems and Reforms
- Lipoproteins and Cardiovascular Health
- Liver Disease and Transplantation
- Cardiac electrophysiology and arrhythmias
- Fatty Acid Research and Health
- Fetal and Pediatric Neurological Disorders
- Eicosanoids and Hypertension Pharmacology
- Cardiovascular and exercise physiology
- Mobile Health and mHealth Applications
- Pulmonary Hypertension Research and Treatments
Caritas Hospital
2018-2023
Little Flower Hospital & Research Centre
2023
<h3>Importance</h3> Wide heterogeneity exists in acute myocardial infarction treatment and outcomes India. <h3>Objective</h3> To evaluate the effect of a locally adapted quality improvement tool kit on clinical process measures Kerala, southern Indian state. <h3>Design, Setting, Participants</h3> Cluster randomized, stepped-wedge trial conducted between November 10, 2014, 9, 2016, 63 hospitals India, with last date follow-up December 31, 2016. During 5 predefined steps over study period,...
Data on the burden of acute heart failure (AHF) admissions, practice patterns, and outcomes are rare from India other low- middle-income countries. We aimed to describe baseline characteristics, guideline-directed medical therapy (GDMT) prescribing patterns 90-day mortality rates in patients admitted with AHF Kerala, India.
<h3>Importance</h3> Ischemic heart disease is the leading cause of death in India, and treatment can be costly. <h3>Objective</h3> To evaluate individual- household-level costs impoverishing effects acute myocardial infarction among patients Kerala, India. <h3>Design, Setting, Participants</h3> This investigation was a prespecified substudy Acute Coronary Syndrome Quality Improvement Kerala study, stepped-wedge, cluster randomized clinical trial conducted between November 2014 2016 across 63...
We report patient characteristics, treatment pattern and one-year clinical outcome of nonvalvular atrial fibrillation (NVAF) from Kerala, India. This cohort forms part Kerala Atrial Fibrillation (KERALA-AF) registry which is an ongoing large prospective study. KERALA-AF collected data adults with previously or newly diagnosed (AF) during April 2016 to 2017. A total 3421 patients were recruited 53 hospitals across state. analysed follow-up 2507 NVAF. Mean age at recruitment was 67.2 years...
This retrospective study compares admissions and outcomes due to acute decompensated heart failure (ADHF) during the COVID-19 pandemic from 25 March July 2020 with historical patient control who were admitted same period in 2019. Data of participating hospitals was collected analysed ICC NHFR (Indian College Cardiology National Heart Failure Registry) for 2019 2020. Total number ADHF admissions, demographics, aetiology, co-morbid conditions in-hospital mortality compared analysed. A...
Short term outcomes of patients with pulmonary hypertension are not available from low and middle-income countries including India. We conducted a prospective study 2003 hypertension, 50 centres (PROKERALA) in Kerala, who were followed up for one year. Pulmonary (PH) was mainly diagnosed on the basis Doppler echocardiography. The primary outcome composite end-point all-cause death hospital admission heart failure. All cause hospitalisation events constituted secondary outcome. Mean age...
<ns4:p><ns4:bold>Background: </ns4:bold>Heart failure (HF) is a debilitating condition associated with enormous public health burden. Management of HF complex as it requires care-coordination different cadres care providers. We propose to develop team based collaborative model (CCM), facilitated by trained nurses, for management the support mHealth and evaluate its acceptability effectiveness in Indian setting.</ns4:p><ns4:p> <ns4:bold>Methods: </ns4:bold>The proposed study will use...
The presentation and outcomes of acute decompensated heart failure (ADHF) during COVID times (June 2020 to Dec 2020) were compared with the historical control same period in 2019. Data 4806 consecutive patients HF admitted 22 centres country collected this period. admission patterns, aetiology, outcomes, prescription guideline-directed medical therapy (GDMT) interventions analysed retrospective study. Admissions for pandemic decreased by 20% corresponding six-month 2019, numbers dropping...
Aims: Heart Failure (HF) is a growing epidemic globally and challenging situation particularly for country like India. There paucity of data in the Indian context College Cardiology National Registry (ICCNHFR) would be first its kind understanding aetiology, demographics treatment pattern country. The rationale design study described. Methods Results: This prospective observational registry Acute Decompensated (ADHF) across various hospitals include consecutive adult patients admitted with...
Heart failure (HF) is a multi-morbid chronic condition, which adversely affects the quality of life affected individual. Engaging patient and their caregivers in self-care known to reduce mortality, rehospitalisation improve among HF patients. The PACT-HF trial will answer whether clinical benefits terms mortality hospitalisation outcomes can be demonstrated by using pragmatic design explore specific effects physical activity, cognitive behavioural therapy patients India.
<ns4:p><ns4:bold>Background: </ns4:bold>Heart failure (HF) is a debilitating condition associated with enormous public health burden. Management of HF complex as it requires care and coordination different cadres providers. In resource poor settings, physician driven initiatives to improve management difficult due multiple barriers. We propose develop team based collaborative model (CCM), facilitated by trained nurse, for the support mHealth evaluate their acceptability effectiveness in...
In India, data from large HF registries has demonstrated significantly lower 5-year mortality rates for patients with HFrEF discharged on guideline-directed medical therapy (GDMT), revealing an important target intervention to improve clinical outcomes. Hospital-based quality improvement initiatives increase of GDMT at hospital discharge have had limited effect, suggesting additional strategies are needed in patients. Polypills been proposed as implementation strategy simplify the current...
Background: Reports on patients with Non valvular Atrial Fibrillation (NVAF) particularly in the elderly are few from India. This paper focuses multimorbidity pattern, antithrombotic treatment and mortality of NVAF state Kerala. India.Methods: Clinical details age ≥ 75 years cohort KERALA-AF registry were analyzed for pattern multimorbidity, one- year mortality.Findings: The study comprised 753 a median 80 (IQR=77- 84) 53.5% male. Multimorbidity was present 94.5% patients. Hypertension...
Sex differences in presentation, management, and outcomes of heart failure (HF) have been observed, but it is uncertain whether these exist South India.We describe sex in-hospital patients hospitalized with HF India explore sex-based the effect quality improvement intervention a secondary analysis prospective, interrupted time series study.The Heart Failure Quality Improvement Kerala (HF QUIK) study evaluated toolkit on process care measures clinical eight hospitals using an design from...