A5101829646- Catalytic C–H Functionalization Methods
- Click Chemistry and Applications
- Advanced biosensing and bioanalysis techniques
- Antibiotic Resistance in Bacteria
- Chemical Synthesis and Analysis
- Synthesis and Catalytic Reactions
- Catalytic Cross-Coupling Reactions
- Salmonella and Campylobacter epidemiology
- Biosensors and Analytical Detection
- Catalytic Alkyne Reactions
- Food Quality and Safety Studies
- Identification and Quantification in Food
- Biofuel production and bioconversion
- Extracellular vesicles in disease
- CRISPR and Genetic Engineering
- Enzyme Production and Characterization
- Cyclopropane Reaction Mechanisms
- Pharmaceutical and Antibiotic Environmental Impacts
- Biopolymer Synthesis and Applications
- Garlic and Onion Studies
- SARS-CoV-2 detection and testing
- Bacteriophages and microbial interactions
- Agriculture, Soil, Plant Science
- Advanced Nanomaterials in Catalysis
- Sulfur-Based Synthesis Techniques
Kyungpook National University
2024-2025
Konkuk University
2021-2024
Ministry of Food and Drug Safety
2020-2024
National Institute of Food and Drug Safety Evaluation
2017-2021
Seoul National University
2004-2020
Bucheon University
2016-2020
Soonchunhyang University
2017-2020
Seoul National University of Science and Technology
2017
Daejeon University
2014
Chungnam National University
2014
We report the direct amidation of arene C–H bonds using sulfonyl azides as amino source to release N2 single byproduct. The reaction is catalyzed by a cationic rhodium complex under external oxidant-free conditions in atmospheric environment. A broad range chelate group-containing arenes are selectively amidated with excellent functional group tolerance, thus opening new avenue practical intermolecular C–N bond formation.
4-Substituted 1-(N-sulfonyl)-1,2,3-triazoles are selectively obtained by using the Cu-catalyzed azide–alkyne cycloaddition reaction with sulfonyl azides. Performing at 0 °C in chloroform presence of 2,6-lutidine and CuI as catalyst effectively prevents ketenimine pathway provides convenient access to N-sulfonyltriazoles good excellent yields. Supporting information for this article is available on WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z604241_s.pdf or from author. Please...
Pd-Catalyzed oxidative alkynylation of azoles with terminal alkynes was developed via simultaneous activation both heterocyclic sp(2) C-H and alkynyl sp bonds. The choice palladium catalyst source external base resulted in being important factors for performing the reaction high efficiency selectivity, air successfully utilized as an environmental oxidant present procedure.
A highly efficient and versatile Pd-catalyzed direct alkynylation reaction of heterocycles with 1-bromoalkynes was developed. The substrate scope the very broad to include not only azoles but also azolines for first time, thus offering an important advance in functionalization heterocycles.
Colorectal cancer (CRC) as the second leading cause of global deaths poses critical challenges in clinical settings. Cancer-derived small extracellular vesicles (sEVs), which are secreted by cells, have been shown to mediate tumor development, invasion, and even metastasis, thus received increasing attention for development diagnostic or therapeutic platforms. In present study, sEV-targeted systematic evolution ligands exponential enrichment (E-SELEX) is developed generate a high-quality...
Phosphoryl azide was successfully employed as an efficient reacting partner in the Cu-catalyzed three-component reaction with 1-alkynes and amines to produce corresponding phosphoryl amidines high yields. A range of fruitful applicability produced also demonstrated such alkoxide exchange asymmetric alpha-alkylation optically active BINOL-derived amidines.
Nanomesh electronics, renowned for their breathability and compatibility with long-term skin attachment, face significant challenges in achieving high-resolution micropatterning, which limits applications advanced devices. To address this, a method to fabricate durable, breathable, highly conductive micropatterned nanomesh electrodes (MPNEs) line widths as narrow 10 μm was developed. Using double-side exposure technique, precise patterning achieved on polyimide substrate. Silver nanowires...
Colistin is an important antibiotic currently used to manage infections caused by multidrug-resistant pathogens in both humans and livestock animals. A new mobile colistin-resistance (mcr-9) gene was recently discovered; this discovery highlighted the need for rigorous monitoring of bacterial resistance against colistin. Salmonella one major responsible foodborne illnesses; however, there minimal information regarding presence mcr genes strains. The aim study investigate among 178 strains...
Astaxanthin (AST) exhibits potent antioxidant and anti-inflammatory activities but poor stability biological efficacy, which limit its application in the food medical industries. In present study, a new strategy was proposed to enhance of AST using fetal bovine serum-derived extracellular vesicles (EVs). Saponin-assisted incubation used load owing high encapsulation efficiency loading capacity. AST-incorporated EVs (EV-ASTs) maintained their original EV morphology showed at 4 °C, 25 37 °C...
The inhibitory effect of an onion extract on browning potato was investigated. addition the heated to exhibited a marked polyphenol oxidase and formation brown color. dependent upon its heating temperature. both glycine glucose increased toward oxidase.
This study was to investigate the prevalence and characteristics of antimicrobial-resistant Staphylococcus aureus methicillin-resistant S. (MRSA) from 4,264 retail meat samples including beef, pork, chicken in Korea between 2013 2018. A broth microdilution antimicrobial susceptibility testing performed for aureus. Molecular typing by multilocus sequence (MLST), spa typing, pulsed-field gel electrophoresis (PFGE), on mecA-positive strain. isolated at a rate 18.2% (777/4,264), which MRSA...