A5101494835- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Colorectal and Anal Carcinomas
- Intraperitoneal and Appendiceal Malignancies
- Neuroendocrine Tumor Research Advances
- Genital Health and Disease
- Reproductive tract infections research
- Chromatin Remodeling and Cancer
- Lung Cancer Research Studies
- Gestational Trophoblastic Disease Studies
- Lymphoma Diagnosis and Treatment
- Pelvic floor disorders treatments
- Cancer-related molecular mechanisms research
- Cancer Diagnosis and Treatment
- Gynecological conditions and treatments
- Cancer Research and Treatments
- Hepatitis B Virus Studies
- Pregnancy and preeclampsia studies
- Cancer survivorship and care
- Cancer Immunotherapy and Biomarkers
- Global Cancer Incidence and Screening
- Gastric Cancer Management and Outcomes
Chang Gung Memorial Hospital
2016-2025
Chang Gung University
2016-2025
Linkou Chang Gung Memorial Hospital
2011-2024
National Sun Yat-sen University
2007-2024
Keelung Chang Gung Memorial Hospital
2014-2022
Weatherford College
2005-2022
Memorial Hospital of South Bend
1992-2022
Bridge University
2022
Asia University
2018
Kaohsiung Chang Gung Memorial Hospital
2016-2017
To assess the diagnostic accuracy of fused T2-weighted and high-b-value diffusion-weighted (DW) magnetic resonance (MR) images at 3 T for evaluation myometrial invasion in patients with endometrial cancer.Institutional review board approval informed consent were obtained. From May 2006 to October 2007, 48 consecutive aged 25-80 years (mean age, 57 years) who had cancer prospectively enrolled preoperative by using a 3-T MR unit. Two radiologists interpreted depth on images, dynamic contrast...
Purpose To compare the diagnostic accuracy of contrast‐enhanced (CE) magnetic resonance imaging (MRI) and diffusion‐weighted MRI (DWI) in differentiation between uterine leiomyosarcoma (LMS) / smooth muscle tumor with uncertain malignant potential (STUMP) benign leiomyoma. Materials Methods A consecutive cohort 8 LMS/STUMP 25 leiomyomas underwent pelvic exam at 3T. Two radiologists independently evaluated images based on CE‐MRI (central nonenhancement equilibrial phase) DWI (hyperintensity b...
BACKGROUND The purpose of this study was to investigate pretreatment variables that could predict prognosis and evaluate the impact postoperative adjuvant therapy on outcomes patients with Stage IB or II cervical carcinoma without pelvic lymph node metastases. METHODS Eight hundred ninety-one who underwent radical hysterectomy bilateral lymphadenectomy as primary treatment at a single institution were analyzed. Potential prognostic studied. RESULTS Among be assessed before treatment, depth...
The role of positron emission tomography (PET) with [18F]-fluoro-2-deoxy-D-glucose (FDG) in early-stage cervical cancer is unclear. We aimed to investigate the clinical benefit FDG-PET primary staging before radical hysterectomy and pelvic lymphadenectomy (RH-PLND).Patients untreated stage IA2 IIA adenocarcinoma (AD) or adenosquamous carcinoma (ASC) nonbulky (< = 4 cm) squamous cell magnetic resonance imaging (MRI) -defined negative nodal metastasis were enrolled onto a prospective study...
We investigated the prevalence of minor psychiatric morbidity in a group women who were pregnant during or immediately after major earthquake disaster and we prognostic factors that may have influenced perinatal outcome pregnancy. The study was initiated 6 months enrolled 171 town near epicentre. A Post-Earthquake Questionnaire, Chinese Health Questionnaire (CHQ-12) posttraumatic stress disorder (PTSD) symptoms checklist completed before delivery while data retrieved from hospital...
Ovarian cancers are frequently not diagnosed until advanced stages, resulting in a high case fatality rate. Because of this, more tumor markers, addition to CA125, for detecting and monitoring ovarian cancer needed. During systematic search potential biomarkers cancer, we compared the protein profiles between interstitial fluid normal ovaries, rationalizing that abnormal levels proteins may be detected peripheral blood thus serve as easily accessible markers. Here, show stress-induced...
To define the dose-limiting toxicity (DLT), maximum tolerated dose (MTD) and pharmacokinetics (PK) of PEP02, a novel liposome-encapsulated irinotecan, in patients with advanced refractory solid tumors. Patients were enrolled cohorts one to three receive escalating PEP02 phase I trial. from 60 180 mg/m2, was given as 90-min intravenous infusion, every 3 weeks. A total 11 into levels: (one patient), 120 (six patients) mg/m2 (four patients). DLT observed patients, at (grade catheter-related...
Abstract BACKGROUND The clinical value of positron emission tomography (PET) with [ 18 F]fluoro‐2‐deoxy‐D‐glucose (FDG) for primary staging in cervical carcinoma appears to be promising. authors sought evaluate the diagnostic efficacy and benefit PET restaging at time first recurrence. METHODS Forty patients who experienced confirmed treatment failure but were feasible candidates curative salvage therapy enrolled prospectively current study. Restaging was performed computed and/or magnetic...
In an attempt to understand the molecular mechanisms for different clinical features between adenocarcinoma/adenosquamous carcinoma (AC/ASC) and squamous (SC) of uterine cervix, we analyzed gene expression profiles histological subtypes cervical cancer. Cancer specimens surrounding normal tissue counterparts were separately collected from cancer patients undergoing type III radical hysterectomy. Paired total RNA (cancer tissues) was isolated with cDNA microarrays containing duplicate spots 7...
Stress-induced phosphoprotein 1 (STIP1) has been recently identified as a released biomarker in human ovarian cancer. In addition, STIP1 secreted by cancer cells shown to promote tumor cell proliferation binding ALK2 (activin A receptor, type II-like kinase 2) and activating the SMAD-ID3 signaling pathways. this study, total of 330 samples were evaluated for expression immunohistochemistry analyzed possible correlation with patient characteristics survival. The quantification...
Objective Growing evidence suggests that fertility-preserving treatment is feasible for young women with early-stage, low-grade endometrial carcinoma. However, published data on their long-term outcomes and prognostic factors remain scanty. We aimed to investigate the of receiving treatment. Methods Between 1991 2010, grade 1 endometrioid carcinoma at presumed stage IA (without myometrial invasion) who underwent megestrol acetate 160 mg/d or without other hormonal agents were retrospectively...