A5052492166- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Obstructive Sleep Apnea Research
- Inhalation and Respiratory Drug Delivery
- Sinusitis and nasal conditions
- Chronic Disease Management Strategies
- Sleep and related disorders
- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Nursing Diagnosis and Documentation
- Pediatric health and respiratory diseases
- Dementia and Cognitive Impairment Research
- Sleep and Work-Related Fatigue
- Respiratory and Cough-Related Research
- Heart Failure Treatment and Management
- Childhood Cancer Survivors' Quality of Life
- Physical Activity and Health
- Injury Epidemiology and Prevention
- Cardiovascular and Diving-Related Complications
- Adrenal Hormones and Disorders
- Obesity, Physical Activity, Diet
- Delphi Technique in Research
- Machine Learning in Healthcare
- Thermal Regulation in Medicine
Psychiatry Baselland
2014-2021
University of Basel
2014-2021
Kantonsspital Baselland
2015-2017
Hospital Base
2016
Kantonsspital Aarau
2014-2015
University Medical Center Freiburg
2014-2015
Kantonsspital Münsterlingen
2015
University Hospital of Basel
2011-2014
Ramboll (United Kingdom)
2014
Luzerner Kantonsspital
2014
<h3>Importance</h3>International guidelines advocate a 7- to 14-day course of systemic glucocorticoid therapy in acute exacerbations chronic obstructive pulmonary disease (COPD). However, the optimal dose and duration are unknown.<h3>Objective</h3>To investigate whether short-term (5 days) treatment patients with COPD exacerbation is noninferior conventional (14 clinical outcome it decreases exposure steroids.<h3>Design, Setting, Patients</h3>REDUCE (Reduction Use Corticosteroids Exacerbated...
The burden of asthma and COPD among patients is high people affected are frequently hospitalized due to exacerbations. There numerous reasons for the lack disease control in patients. It associated with non-adherence guidelines on part health care provider poor inhalation technique and/or prescribed treatment plan by patient. This study aims present data inhaler its impact quality life (QoL) symptom a typical population chronic lung from randomized controlled trial medication adherence. For...
<b><i>Background:</i></b> The occurrence of both chronic obstructive pulmonary disease (COPD) and sleep apnea (OSA) in an individual patient has been described as ‘overlap syndrome', which associated with poor prognosis. Little is known about the possible predictors overlap syndrome its association comorbidities contributing to impaired outcome. <b><i>Objectives:</i></b> This study aimed evaluate prevalence a cohort COPD patients....
Several studies have demonstrated that fully automated pattern recognition methods applied to structural magnetic resonance imaging (MRI) aid in the diagnosis of dementia, but these conclusions are based on highly preselected samples significantly differ from seen a dementia clinic.At single clinic, we evaluated ability linear support 1 Some data used preparation this article were obtained Alzheimer's Disease Neuroimaging Initiative (ADNI) database (http://adni.loni.usc.edu).
In the therapy of chronic obstructive pulmonary disease (COPD), it is a major goal to improve health-related quality life (HRQOL). Patients with COPD often suffer from exertional dyspnea and adopt sedentary lifestyle, which could be associated poorer HRQOL. The aim this study was investigate independent association objectively measured daily physical activity functional capacity HRQOL in patients COPD.In cross-sectional conducted at University Hospital Basel, Switzerland, 87 stable (58.6%...
Abstract Background Poor medication-adherence is common in chronic lung patients, resulting reduced health-outcomes and increased healthcare-costs. This study aimed to investigate the impact of an acoustic reminder support calls on adherence inhaled therapy asthma COPD patients determine their effect exacerbations. Methods single-blinded randomized controlled trial investigated during 6 months ambulatory setting. The intervention consisted daily alarm clock phone calls, whenever use rescue...
In our study, we aimed to characterise adult childhood cancer survivors (ACCS), assess their health issues, gauge health-related quality of life (HRQOL) and evaluate visit satisfaction.
Summary Sleep problems are a well‐known risk factor for work injuries, but less is known about which vulnerable populations most at risk. The aims of this study were to investigate the association between sleep quality and injury identify factors that may modify association. A case–control including 180 cases 551 controls was conducted University Hospital in Basel, Switzerland, from 1 December 2009 30 June 2011. Data on injuries collected. Adjusted odds ratios 95% confidence intervals...
To analyze prospectively the hypothalamic-pituitary-adrenal (HPA) axis and clinical outcome in patients treated with prednisone for exacerbated chronic obstructive pulmonary disease (COPD).Prospective observational study.Patients presenting to emergency department were randomized receive 40 mg daily 5 or 14 days a placebo-controlled manner. The HPA was longitudinally assessed 1 μg corticotropin test hypocortisolism score at baseline, on day 6 before blinded treatment, hospital discharge, up...
<b><i>Background:</i></b> Existing prediction models for mortality in chronic obstructive pulmonary disease (COPD) patients have not yet been validated primary care, which is where the majority of receive care. <b><i>Objectives:</i></b> Our aim was to validate ADO (age, dyspnoea, airflow obstruction) index as a predictor 2-year 2 general practice-based COPD cohorts. <b><i>Methods:</i></b> Six hundred and forty-six with...
The Global Initiative for Chronic Obstructive Lung Disease proposed in 2011 a new system to classify chronic obstructive pulmonary disease (COPD) patients into risk groups A-D, which considers symptoms and future exacerbation grade severity. aim of this study was investigate the agreement between COPD group classifications using assessment test (CAT) or modified Medical Research Council (mMRC) severity grades past-year exacerbations. Furthermore, physical activity across examined. 87 with...
(1) Introduction: Chronic obstructive pulmonary disease (COPD) and its associated morbidity mortality are a global burden on both affected patients healthcare systems. The Global Initiative for Obstructive Lung Disease (GOLD) issues guidelines with the aim of improving COPD management. Previous studies reported significant variability in adherence to these recommendations. objective this study was evaluate Swiss primary practitioners' GOLD pharmacological treatment stable COPD. (2) Methods:...
The aim of this study was to assess the feasibility, acceptability and effectiveness a pilot COPD integrated care programme implemented in Valais, Switzerland.The adapted from self-management Living Well with COPD, included following elements: patient-education group sessions, telephone medical follow-ups, multidisciplinary teams, training healthcare professionals, evidence-based care. A process outcome evaluation phase conducted by means qualitative quantitative methods. Reach (coverage,...
Background . Patients with Chronic Obstructive Pulmonary Disease (COPD) suffer from increased daytime sleepiness. The aim of this study was to identify potential predictors subjective sleepiness special regard sleep-related breathing disorder and nocturnal activity. Methods COPD patients were recruited at the University Hospital Basel, Switzerland. risk groups A–D determined according spirometry Assessment Test (CAT). Breathing evaluation performed ApneaLink device. Nocturnal energy...
The Swiss COPD cohort was established in 2006 to collect data a primary care setting. objective of this study evaluate possible predictive factors for exacerbation and re-exacerbation. In order predict until the next visit based on knowledge since last visit, multistate model described by Therneau Grambsch performed. Data 1,247 patients (60.4% males, 46.6% current smokers) were analyzed, 268 (21.5%) did not fulfill spirometric diagnostic criteria COPD. 748 (63% 44.1% available analysis. an...
Objective: With respect to the overweight epidemic, this study aimed investigate association between domain-specific physical activity and body composition measures in Swiss male employees. Methods: A total of 192 healthy adults full-time employment were investigated. Height, weight, waist circumference measured mass index was calculated. Relative fat relative muscle determined by bioelectric impedance analysis. Physical assessed validated International Activity Questionnaire. Results: In...
Background Obstructive sleep apnea syndrome (OSAS) is common in adults. People with OSAS have a higher risk of experiencing traffic accidents and occupational injuries (OIs). We aimed to clarify the diagnostic performance three-channel screening device (ApneaLinkTM) compared gold standard full-night attended polysomnography (PSG) among hospital outpatients not referred for sleep-related symptoms. Furthermore, we determine whether manual revision ApneaLinkTM autoscore enhanced performance....
Some sleep disorders are known risk factors for occupational injuries (OIs). This study aimed to compare the prevalence of obstructive apnea syndrome (OSAS) in a population patients with OIs admitted emergency room (ER) hospital outpatients as controls. Seventy-nine and 56 controls were recruited at University Hospital Basel, Switzerland between 2009 2011. All completed questionnaire underwent full-night attended polysomnography (PSG). We considered an apnea–hypopnea index (AHI) > 5 abnormal...
Despite important advances in diagnosis and medical therapy of heart failure (HF), disease monitoring guidance remains to be based on clinical signs symptoms. NT-proBNP was repeatedly demonstrated a strong independent predictor morbidity mortality patients with HF. Only few – conflicting data are available the efficacy serial measurement as tool for treatment These limited outpatient setting. Currently, no effects this approach hospitalized acute decompensated The goal study is explore...
Introduction: Serial N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurements have proven to be useful for therapy monitoring in patients hospitalized acute decompensated heart failure (ADHF). The POC-HF pilot study investigated whether serial NT- proBNP influenced treatment decisions these patients. Methods: Patients ADHF were randomly assigned an intervention group (serial NT-proBNP made available treating physicians) or a control (care as usual). HF was administered at the...
Leuppi, Jörg D.*; Schuetz, Philipp†; Bingisser, Roland‡; Bodmer, Michael‡; Briel, Matthias§; Drescher, Tilman*∥; Duerring, Ursula∥; Henzen, Christoph¶; Leibbrandt, Yolanda#; Maier, Sabrina*; Miedinger, David*; Müller, Beat†; Scherr, Andreas*; Schindler, Christian**; Stoeckli, Rolf∥; Viatte, Sebastien#††; Von Garnier, Christophe‡‡; Tamm, Michael§§; Rutishauser, Jonas#∥∥ Author Information
<b>Aim:</b> The aim of this study is to investigate the effects an acoustic reminder on medication adherence in lung patients. <b>Methods:</b> In on-going prospective single-blind randomized controlled trial, in- and outpatients from several hospitals around Basel diagnosed with asthma or COPD prescribed inhalative were recruited. They must have experienced at least one exacerbation previous 12 months. intervention group provided for inhalation receives support calls when not taken as...