A5100733951- Ophthalmology and Eye Disorders
- Cerebral Venous Sinus Thrombosis
- Advanced Neuroimaging Techniques and Applications
- Osteoarthritis Treatment and Mechanisms
- Cancer Mechanisms and Therapy
- Glaucoma and retinal disorders
- Pituitary Gland Disorders and Treatments
- Knee injuries and reconstruction techniques
- Diabetes Management and Research
- Total Knee Arthroplasty Outcomes
- Asthma and respiratory diseases
- Cerebrovascular and Carotid Artery Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Medical Image Segmentation Techniques
- Mechanisms of cancer metastasis
- Thyroid Disorders and Treatments
- Infrared Thermography in Medicine
- Diabetic Foot Ulcer Assessment and Management
- Cardiovascular Function and Risk Factors
- MRI in cancer diagnosis
- Coffee research and impacts
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Brain Tumor Detection and Classification
- Advanced MRI Techniques and Applications
- Diabetes and associated disorders
Jiangsu Province Hospital
2014-2025
Nanjing Medical University
2014-2025
Tianjin Hospital
2024
Yangpu Hospital of Tongji University
2024
Air Force Medical University
2011-2012
Nanjing Maternity and Child Health Care Hospital
2010
Zhongda Hospital Southeast University
2009
Purpose: To investigate the potential causal relationship between coffee consumption and osteoarthritis (OA), to disentangle whether body mass index (BMI) Bone mineral density (BMD) mediate this relationship. Methods: We performed two-sample two-step Mendelian randomization (MR) analyses utilizing publicly available genome-wide association studies (GWAS) summary statistics estimate intake OA risk (including knee OA, hip or total OA), as well possible mediating effects of BMI BMD. In...
To investigate the effects of different subtypes lipohypertrophy (LH) on insulin total daily dose (TDD) requirements in patients with type 1 diabetes mellitus (T1DM), and to propose subtype-specific dosage adjustment strategies after avoiding injection at sites LH. This prospective observational study enrolled hospitalised T1DM a disease duration ≥1 year. Point-of-care ultrasound was performed immediately their admission determine presence specific An pump installed away from LH each...
Introduction Knee osteoarthritis (KOA) is a prevalent condition often associated with decline in patients’ physical function. Objective self-assessment of conditions poses challenges for many advanced KOA patients. To address this, we explored the potential computer vision method to facilitate home-based function self-assessments. Methods We developed and validated simple at-home artificial intelligence approach recognize joint stiffness levels individuals KOA. One hundred four knee patients...
Objective:We aimed to investigate the ability of readout-segmented echo-planar imaging (rs-EPI)-based diffusion tensor (DTI) in assessing microstructural change extraocular muscles (EOMs) and optic nerves patients with thyroidassociated orbitopathy (TAO) as well evaluating disease activity.Materials Methods: We enrolled 35 TAO 22 healthy controls (HCs) who underwent pre-treatment rs-EPIbased DTI.Mean, axial, radial diffusivity (MD, AD, RD) fractional anisotropy (FA) medial lateral EOMs nerve...
Abstract Background Knee osteoarthritis (KOA) is a highly disabling disease, and studying its progression crucial. However, it still unclear whether the of ipsilateral knee influenced by contralateral osteoarthritis. Methods Data were collected from OAI database divided into two study cohorts (right/left KOA cohort). Each cohort had target knee) was further groups (exposure/control group). The demographic data both balanced at baseline propensity score matching (PSM), included rating scale...
Discriminating the stage of thyroid-associated ophthalmopathy (TAO) is crucial for treatment strategy and prognosis prediction. Utility conventional magnetic resonance imaging in disease staging limited.To investigate performance T2 mapping based on different region interest (ROI) selection methods TAO.Thirty-two patients with TAO were retrospectively enrolled. Two radiologists independently measured relaxation time (T2RT) extraocular muscles using two ROIs (hotspot [ROIHS]: T2RT-hot;...
Objective To report the efficacy, long-term safety, and tolerability of using a small dose (125 mg/m2 weekly for 4 weeks) rituximab to treat Chinese patients with thyroid-associated ophthalmopathy (TAO). Methods Seven active moderate-to-severe TAO were prospectively recruited in this study. A (125mg/m2 body surface area) was given duration four weeks. Thyroid function, thyrotropin receptor antibody (TRAb), B cell T subsets, ophthalmological examination, magnetic resonance imaging derived...
To evaluate the value of MRI-based texture analysis extraocular muscle (EOM) and orbital fat (OF) in monitoring predicting response to glucocorticoid (GC) therapy patients with thyroid-associated ophthalmopathy (TAO).Thirty-seven active moderate-to-severe TAO (responders, n = 23; unresponders, 14) were retrospectively enrolled. parameters (entropy, uniformity, skewness kurtosis) EOM OF measured before after GC therapy, compared between groups. Correlations changes clinical activity score...
The treatment of thyroid associated ophthalmopathy (TAO) is still a worldwide problem.The conventional glucocorticoid therapy can not benefit all the patients.In recent years,new immunosuppressive agents,such as tumor necrosis factor inhibitors and anti-CD20 monoclonal antibody have been emerging serving new targets in treating TAO to remedy insufficiency treatment.In this paper,recent advances immunotherapy are reviewed. Key words: Thyroid ophthalmopathy; Immunotherapy; ...
Objective To investigate the diagnosis method in patients after polyacrylamide hyarogel injection for augmentation mammoplasty preoperative surgical design. Methods 3-dimensional reconstruction of Magnetic resonance hydrography (MRH)was performed on mammoplasty. The images were observed to understand distribution and location hyarogel. operation was guided by results.Results 7 underwent MRH examination 6 cases received operation. consistent with results. Conclusions can be displayed clearly...