A5102775452- Ferroptosis and cancer prognosis
- Colorectal Cancer Treatments and Studies
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Hypoxia, and Metabolism
- Immune cells in cancer
- Wound Healing and Treatments
- RNA modifications and cancer
- CAR-T cell therapy research
- Gastric Cancer Management and Outcomes
- Peptidase Inhibition and Analysis
- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- Platelet Disorders and Treatments
- Liver Disease and Transplantation
- Cardiac Fibrosis and Remodeling
- Monoclonal and Polyclonal Antibodies Research
- Gallbladder and Bile Duct Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Cell Adhesion Molecules Research
- Organ Transplantation Techniques and Outcomes
- RNA regulation and disease
Chengdu University of Technology
2025
Fourth Hospital of Hebei Medical University
2025
University of South China
2024
PLA Information Engineering University
2024
Niigata University
2024
Xi’an University
2024
Peking Union Medical College Hospital
2021-2023
Peking University
2015-2023
Peking University Third Hospital
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2023
Clinical settings often face significant obstacles in treating large acute wounds. The alternative of therapeutic approach is needed urgently. Hydrogels derived from natural or synthetic materials may be designed to perform a variety functions for promoting wound healing. Herein, 3D bioprinted hydrogel patch accelerating healing, which fabricated with methacryloyl-substituted gelatin (GelMA) and silk fibroin (SilMA) dual-cross-linked by ultraviolet (UV) light. GelMA added (GelSilMA) shows...
// Yago Pico de Coaña 1 , Maria Wolodarski 1, 2 Isabel Poschke 3 Yuya Yoshimoto 4 Yuan Yang 5 Nyström Ulrika Edbäck Suzanne Eghyazi Brage Andreas Lundqvist 6 Giuseppe V. Masucci Johan Hansson Rolf Kiessling Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden University Hospital Solna, Division Molecular Gastrointestinal Tumors, German Research Center, Heidelberg, Germany Radiation Oncology, Gunma Graduate School Medicine, Maebashi, Gunma,...
Factors released from glioma-associated microglia/macrophages (GAMs) play a crucial role in glioblastoma multiforme (GBM) progression. Here, we study the importance of CCL18, cytokine expressed human but not rodent GAMs, as modulator glioma growth. Since CCL18 signaling could be studied classical mouse models, developed an approach by transplanting induced pluripotent stem cell-derived microglia and cells into brain slices depleted their intrinsic microglia. We observe that promotes cell...
This paper reports the results of exploratory research on reproductive and sexual health knowledge behaviour young, unmarried women who migrate to cities from rural areas for work, their access needs in relation family planning Beijing, Guangzhou, Shanghai, Guiyang Taiyuan, China. Focus group discussions were conducted with 146 young aged 16–25 58 in-depth interviews key informants. Some female migrant workers sexually active living boyfriends, most whom expected marry each other. Most...
Adoptive cell therapy (ACT) is becoming a prominent alternative therapeutic treatment for cancer patients relapsing on traditional therapies. In parallel, antibodies targeting immune checkpoint molecules, such as cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) and death protein 1 pathway (PD-1), are rapidly being approved multiple types, including first line PD-L1-expressing non-small-cell lung cancer. The combination of ACT blockade could substantially boost the efficacy ACT. this...
Triple-negative breast cancer (TNBC) is a common malignant disease among females and severely threatens the health of women worldwide. Nowadays, circular RNAs (circRNAs) aroused our interest for their functions in human cancers, including TNBC. However, mechanism most circRNAs progression TNBC remains unclear. We found novel circRNA named circATP5C1, whose function uncovered. Tissue microarray was used to analyze association between expression circATP5C1 prognoses patients. Gain-and...
<title>Abstract</title> Rockburst disasters generally occur within specific geological structures. Consequently, predicting and evaluating the potential rockbursts necessitates more focuses on “geological carrier”. Considering structure effects of rockbursts, a novel prediction method based key structures was proposed by combining numerical simulation with neural network. This study systematically investigated typical geomechanical modes rockbursts. An evaluation index for relative energy...
FHL1 has been recognized for a long time as tumor suppressor protein that associates with both the actin cytoskeleton and transcriptional machinery. We present in this study paradigm phosphorylated functions an oncogenic by promoting cell proliferation. The cytosolic tyrosine kinase Src interacts phosphorylates at Y149 Y272, which switches from to growth accelerator. Phosphorylated translocates into nucleus, where it binds transcription factor BCLAF1 promotes growth. Importantly,...
Abstract Colon adenocarcinoma (COAD) is one of the most prevalent malignant tumors worldwide. Immune genes (IGs) have a considerable correlation with tumor initiation and prognosis. The present paper aims to identify prognosis value IGs in COAD conduct model for clinical utility. Gene expression data were downloaded from Cancer Genome Atlas (TCGA), screening analyzing differentially expressed by bioinformatics. Core screened univariate multivariate Cox regression analyses. Survival analysis...
Colorectal cancer (CRC) is one of the most common and deadly malignancies. Novel biomarkers for diagnosis prognosis this disease must be identified. Besides, metabolism plays an essential role in occurrence development CRC. This article aims to identify some critical prognosis-related metabolic genes (PRMGs) construct a model CRC patients clinical use. We obtained expression profiles from The Cancer Genome Atlas database (TCGA), then identified differentially expressed PRMGs by R Perl...
Background: Hepatocellular carcinoma (HCC) is one of the highly heterogeneous cancers that lacks an effective risk model for prognosis prediction. Therefore, we searched angiogenesis-related immune genes affected HCC to construct a and studied role this in HCC. Methods: In study, collected transcriptome data from The Cancer Genome Atlas (TCGA) International Consortium (ICGC) database. Pearson correlation analysis was performed identify association between genes. Consensus clustering applied...
Abstract Background Collagen type XII alpha 1 chain (COL12A1) is associated with human cancer progression. Nevertheless, the expression pattern and function of COL12A1 in intrahepatic cholangiocarcinoma (iCCA) remain unknown. The present study was performed to assess role iCCA. Results A total 1669 genes, differentially expressed between iCCA nontumor liver tissue samples, were identified as potential tumor-specific biomarkers for patients. Of these, significantly upregulated clinical...