A5030430174- Pleural and Pulmonary Diseases
- Ultrasound in Clinical Applications
- Occupational and environmental lung diseases
- Lung Cancer Diagnosis and Treatment
- Trauma Management and Diagnosis
- Amoebic Infections and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pneumothorax, Barotrauma, Emphysema
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Respiratory Support and Mechanisms
- Radiation Dose and Imaging
- Soft tissue tumor case studies
- Radiology practices and education
- Oral and Maxillofacial Pathology
- Sarcoma Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Influenza Virus Research Studies
- Gut microbiota and health
- Congenital Diaphragmatic Hernia Studies
- Cancer Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Hematological disorders and diagnostics
- Airway Management and Intubation Techniques
- Emergency and Acute Care Studies
Queen Alexandra Hospital
2022-2025
Churchill Hospital
2017-2023
University of Oxford
2017-2023
Portsmouth Hospitals NHS Trust
2022-2023
Mater Dei Hospital
2011-2022
Oxford University Hospitals NHS Trust
2017-2021
Oxford Centre for Diabetes, Endocrinology and Metabolism
2017-2019
Norfolk and Norwich University Hospitals NHS Foundation Trust
2019
of clInIcal practIce poIntS Safety and preparation for pleural procedures► Before carrying out a procedure, safety should be taken into consideration. Research questions• Studies to investigate the role fibrinolytic treatment in septated effusion related IPC use MPE patients.• addressing single or dual stiches after insertion.
Rationale: Assessing the early use of video-assisted thoracoscopic surgery (VATS) or intrapleural enzyme therapy (IET) in pleural infection requires a phase III randomized controlled trial (RCT). Objectives: To establish feasibility randomization versus non-surgery as well key outcome measures which are important to identify relevant patient-centered outcomes RCT. Methods: MIST-3 was prospective multicenter All-comers with confirmed diagnosis were enrolled and those ongoing sepsis after up...
Rationale: Sonographic septations are assumed to be important clinical predictors of outcome in pleural infection, but the evidence for this is sparse. The inflammatory and fibrinolysis-associated intrapleural pathway(s) leading septation formation have not been studied a large cohort fluid (PF) samples with confirmed infection matched ultrasound data. Objectives: To assess presence severity against baseline PF PAI-1 (Plasminogen-Activator Inhibitor-1) other proteins as well correlate these...
Corret inhaler technique is recommended by guidelines for optimum asthma care. The objective of the study is to determine real life predictors correct pressurized metered dose (pMDI) in Asthma and COPD patients.Two hundred eight adult patients aged 18+ from respiratory outpatients (69.2%) community on regular pMDI a diagnosis (78.9%) or COPD, were recruited. A questionnaire containing 31 possible was administered with without spacer observed trained researchers 12 point steps, which 4...
<b><i>Background:</i></b> Pleural effusion echogenicity on ultrasound has previously been suggested to allow identification of exudates. A case series that homogenously echogenic effusions are always With modern imaging techniques and more advanced technology, this may no longer be true. <b><i>Objectives:</i></b> This study aims prospectively assess the predictive value in <b><i>Method:</i></b> Patients undergoing...
Introduction and Aims. The first COVID-19 case in Malta was confirmed on the 7th of March 2020. This study is aimed at investigating a significant difference between number acute exacerbations chronic obstructive pulmonary disease (AECOPD) admissions their inpatient outcome Mater Dei Hospital during pandemic when compared to same period 2019. Furthermore, we aim determine predictors mortality AECOPD inpatients. Method. Data collected retrospectively from electronic hospital records periods...
Indwelling pleural catheters (IPC) offer an alternative to talc pleurodesis in recurrent effusion, especially patients wishing avoid hospitalization. Two randomized trials have demonstrated reduced time hospital using IPCs versus malignant effusion (MPE). However, the impact of on services and has not been well studied.To analyze long-term outcomes understand burden terms requirement for visits contacts with healthcare, while IPC was situ.IPC insertions a tertiary center were analyzed...
Rationale: Patients with malignant or paramalignant pleural effusions (MPEs PMPEs) may have tunneled catheter (TPC) management withheld because of infection concerns from immunosuppression associated antineoplastic therapy.Objectives: To determine the rate infections related to TPC use and relationship therapy, immune system competency, overall survival (OS).Methods: We performed an international, multiinstitutional study patients MPEs PMPEs undergoing 2008 2016. were stratified by whether...
Patients with malignant pleural mesothelioma (MPM) or metastases often present effusion (MPE). This study aimed to analyze the effect of fluid on cancer cells.Established patient-derived cell cultures derived from MPE (MPM, breast carcinoma, lung adenocarcinoma) were seeded in 100% (exudate MPM MPE, transudate non-MPE fluid) and proliferation was monitored. In addition, establishment new cultures, specimens, attempted by seeding cells fluid.All established proliferated similar growth rates...
Maged Hassan (MH): I would like to present three cases of patients who presented with symptoms lower respiratory tract infection, fever and cough productive small amount sputum. The had complained for at least 2 weeks before presentation. chest X-rays showed large encysted collections (figure 1A) which required CT delineate the source abnormality. studies (case 1: figure 1B, C; case 2: 2A 3: 2C) caused prolonged discussion between treating clinicians opinions divided on nature lesion in each...
<b><i>Background:</i></b> Indwelling pleural catheters (IPC) are increasingly used for management of recurrent (especially malignant) effusions. Pleural infection associated with IPC use remains a concern. Intrapleural therapy tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) significantly reduces surgical referrals in non-IPC infection, but data on its IPC-related scarce. <b><i>Objective:</i></b> To assess the safety efficacy...