A5030413119- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Advanced Neuroimaging Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Stroke Rehabilitation and Recovery
- Climate Change and Health Impacts
- Healthcare cost, quality, practices
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrospinal fluid and hydrocephalus
- Healthcare Operations and Scheduling Optimization
- Clinical practice guidelines implementation
- Peripheral Artery Disease Management
- Cardiovascular Health and Disease Prevention
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic aneurysm repair treatments
- Cerebral Venous Sinus Thrombosis
- Vascular Malformations Diagnosis and Treatment
- Artificial Intelligence in Healthcare and Education
- Appendicitis Diagnosis and Management
- COVID-19 and healthcare impacts
South Australian Health and Medical Research Institute
2017-2025
Royal Adelaide Hospital
2019-2025
Monash Health
2020-2025
The University of Adelaide
2017-2024
The Royal Melbourne Hospital
2009-2020
The University of Melbourne
2009-2020
John Wiley & Sons (United States)
2019
University College London
2016-2019
Hudson Institute
2019
National Hospital for Neurology and Neurosurgery
2016-2019
Background and Purpose— Intracerebral hemorrhage (ICH) growth predicts mortality functional outcome. We hypothesized that irregular hematoma shape density heterogeneity, reflecting active, multifocal bleeding or a variable time course, would predict ICH growth. Methods— Three raters examined baseline sub-3-hour CT brain scans of 90 patients in the placebo arm Phase IIb trial recombinant activated Factor VII ICH. Each rater, blinded to data, independently applied novel 5-point categorical...
OBJECTIVE Endovascular clot retrieval (ECR) is the standard of care for acute ischemic stroke due to large vessel occlusion. Performing ECR a time critical and complex process involving many specialized providers resources. Maximizing patient benefit while minimizing service cost requires optimization human physical assets. The aim this study develop general computational model an service, which can be used optimize resource allocation. METHODS Using discrete event simulation approach, we...
Rationale No evidence-based acute therapies exist for intracerebral hemorrhage. Intracerebral hemorrhage growth is an important determinant of patient outcome. Tranexamic acid known to reduce in other conditions. Aim The study aims test the hypothesis that patients selected with computed tomography angiography contrast extravasation ‘spot sign’ will have lower rates hematoma when treated intravenous tranexamic within 4·5-hours stroke onset compared placebo. Design Spot sign and On Preventing...
Healthcare waste contributes substantially to the world's carbon footprint. Our aims are review current knowledge of Interventional Radiology (IR) generation and ways reducing in practice, quantify environmental financial impact generated address green initiatives improve IR management.A systematic literature search was conducted July 2022 using Medline Embase databases. The scope included field as well operating theatre literature, where relevant practice.One-hundred articles were reviewed...
Abstract Background Deep learning (DL) algorithms are playing an increasing role in automatic medical image analysis. Purpose To evaluate the performance of a DL model for detection intracranial haemorrhage and its subtypes on non-contrast CT (NCCT) head studies to compare effects various preprocessing design implementations. Methods The algorithm was trained externally validated open-source, multi-centre retrospective data containing radiologist-annotated NCCT studies. training dataset...
<h3>BACKGROUND AND PURPOSE:</h3> Intracerebral hemorrhage growth independently predicts disability and death. We hypothesized that noncontrast quantitative CT densitometry reflects active bleeding improves predictive models of growth. <h3>MATERIALS METHODS:</h3> analyzed 81 the 96 available baseline scans obtained <3 hours post-ICH from placebo arm phase IIb trial recombinant factor VIIa. Fifteen could not be for technical reasons, but characteristics were statistically significantly...
Background Operating rooms contribute between 20% to 70% of hospital waste. This study aimed evaluate the waste burden neurointerventional procedures performed in a radiology department, identify areas for reduction, and motivate new greening initiatives. Methods We audit 17 at tertiary-referral center over 3-month period. Waste was categorized into five streams: general waste, clinical recyclable plastic, paper, sharps. Our department started recycling soft plastics from 13 December 2019....
Background Intrasaccular flow diversion using the woven endobridge device (WEB; MicroVention, Aliso Viejo, CA, USA) for treatment of intracranial aneurysms has demonstrated large scale safety and efficacy. However, limitations arise from its structural configuration, restricting application to specific aneurysm sizes shapes. Technique Overview We introduce CUPCAKE technique, a combination conventional coiling followed by WEB intrasaccular disruption in select cases atypical with technically...
Crohn’s disease (CD) is an immune-mediated, multisystem inflammatory disorder characterised by discontinuous transmural, sometimes granulomatous, inflammation of the gastrointestinal tract. Although it can occur anywhere in tract, has a 70% predilection for terminal ileum. Ileocolonoscopy with biopsy remains gold standard initial diagnosis and assessment CD activity but several limitations, including invasiveness, risk complications cost. With shifting focus towards treatment targets...
Carotid artery stenting (CAS) is an established treatment for carotid stenosis or occlusion. Use of the dual-layer microporous CASPER RX stent has had mixed results in prior reports. The CaRotid Artery Filtering Technique (CRAFT) uses distal end as embolic protection device during deployment. We present largest cohort patients having undergone CAS with and report our multicentre experience CRAFT over last seven years. All undergoing at three tertiary neurointerventional centres Australia...
Abstract Background Endovascular thrombectomy (EVT) for management of large vessel occlusion (LVO) acute ischaemic stroke is now current best practice. Aim To determine if bridging intravenous (i.v.) alteplase therapy confers any clinical benefit. Methods A retrospective study patients treated with EVT LVO was performed. Outcomes were compared between receiving thrombolysis and alone. Primary end‐points reperfusion rate, 90‐day functional outcome mortality using the modified Rankin Scale...
Preserved integrity of the corticospinal tract (CST) is a marker good upper-limb behavior and recovery following stroke. However, there less understanding neural mechanisms that might help facilitate motor in stroke survivors with extensive CST damage. The purpose this study was to investigate resting state functional connectivity chronic different levels damage explore correlates greater performance compromised ipsilesional integrity. Thirty (24 males, aged 64.7 ± 10.8 years) participated...