A5064793746- Seaweed-derived Bioactive Compounds
- Protein Hydrolysis and Bioactive Peptides
- Proteoglycans and glycosaminoglycans research
- Calcium Carbonate Crystallization and Inhibition
- Marine Sponges and Natural Products
- Environmental Toxicology and Ecotoxicology
- Antimicrobial Peptides and Activities
- RNA regulation and disease
- Environmental Chemistry and Analysis
- Bioactive Compounds and Antitumor Agents
- Natural product bioactivities and synthesis
- Mass Spectrometry Techniques and Applications
- Glycogen Storage Diseases and Myoclonus
- Lysosomal Storage Disorders Research
- Marine Biology and Environmental Chemistry
- Computational Drug Discovery Methods
- Advanced Proteomics Techniques and Applications
- Marine Bivalve and Aquaculture Studies
- Enzyme-mediated dye degradation
- Insect Utilization and Effects
- Metabolomics and Mass Spectrometry Studies
- Enzyme Catalysis and Immobilization
- Biomedical Research and Pathophysiology
- Microbial Metabolism and Applications
- Neurological and metabolic disorders
Centre National de la Recherche Scientifique
2016-2025
LIttoral ENvironnement et Sociétés
2019-2025
La Rochelle Université
2020-2024
Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement
2016-2017
Université d'Évry Val-d'Essonne
2016
Biopolymères Interactions Assemblages
2011
Compared to other analytical methods, matrix‐assisted laser desorption ionization mass spectrometry (MALDI‐MS) presents several unique advantages for the structural characterization of degradation products carbohydrates. Our final goal is implement this technique as a high‐throughput platform, with aim exploring natural bio‐diversity discover new carbohydrate depolymerizing enzymes. In approach, variety carbohydrates will be used enzymes substrates and MALDI‐MS employed monitor...
ABSTRACT Favelines, benzocycloheptene diterpenes exclusively found in Cnidoscolus quercifolius , have shown promising anticancer properties, particularly phyllacanthone. Nevertheless, the isolation of these compounds remains challenging due to their similar polarity. The use centrifugal partition chromatography (CPC) has enabled quick and efficient purification phyllacanthone from C. crude extract with a yield 4.5% (w/w) purity 83%. Favelines‐enriched fractions were also obtained purified by...
With the increase in life expectancy, reducing visible signs of skin aging has become a major issue. A reduction collagen and hyaluronic acid synthesis by fibroblasts is feature aging. The green seaweed, Ulva intestinalis, an abundant rich source nutrients, especially proteins peptides. aim this study was to assess potential cosmetic properties protein fraction from intestinalis (PROT-1) containing 51% 22% polysaccharides, its enzymatic peptide hydrolysates on human dermal fibroblasts....
Ports are a good example of how coastal environments, gathering set diverse ecosystems, subjected to pollution factors coming from human activities both on land and at sea. Among them, trace element as copper represents major factor. Abundant in port ecosystem, is transported by runoff water results features (corrosion structures, fuel, anti-fouling products, etc.). The variegated scallop Mimachlamys varia common the Atlantic areas likely be directly influenced pollution, due its sessile...
Cathodic protection is widely used to protect metal structures from corrosion in marine environments using sacrificial galvanic anodes. These anodes, either Zinc, or preferentially nowadays Al-Zn-In alloys, are expected corrode instead of the structures. This leads release dissolved species, Zn2+, Al3+, and In3+, solid phases such as Al(OH)3. Few studies have been conducted on their effects organisms, they concluded that further investigations needed. We therefore evaluated Zn anodes oysters...
Brown seaweeds of the Fucus genus represent a rich source natural antiviral products. In this study, ceranoides hydroalcoholic extract (FCHE) was found to inhibit 74.2 ± 1.3% proteolytic activity free SARS-CoV-2 3CL protease (3CLpro), an enzyme that plays pivotal role in polyprotein processing during coronavirus replication and has been identified as relevant drug discovery target for SARS- MERS-CoVs infections. To purify identify 3CLpro ligands with potential inhibitory using one-step...
Immobilized enzyme reactors (IMERs) are critical tools for developing novel oligosaccharides based on the enzymatic catalysis of polysaccharides. In this paper, a glucuronan lyase from Peteryoungia rosettiformans was produced, purified, and then immobilized CIM® CDI disk cleaving glucuronan. The results showed that around 63.6% glycuronan lyases (800.9 μg) were disk. Vmax values did not significantly change (56.9 ± 4.7 μM∙min−1), while Km (0.310 0.075 g∙L−1) increased by 2.5 times. It is...
Oligosaccharides derived from λ-carrageenan (λ-COs) are gaining interest in the cancer field. They have been recently reported to regulate heparanase (HPSE) activity, a protumor enzyme involved cell migration and invasion, making them very promising molecules for new therapeutic applications. However, one of specific features commercial (λ-CARs) is that they fact heterogeneous mixtures different CARs families, named according thickening purpose product which does not reflect real...
Cathodic protection is widely used to protect metal structures from corrosion and commonly applied on marine in seaports using sacrificial galvanic anodes. These anodes, either Zinc, or preferen-tially nowadays Al-Zn-In alloys, are expected corrode instead of the be protected. This leads release specific dissolved species, Zn2+, Al3+, In3+ solid phases like Al(OH)3. Few studies were conducted effects anodes organisms concluded that further detailed investiga-tions needed controlled...
Oligosaccharides derived from λ-carrageenan (λ-COs) are gaining interest in the cancer field. They have been recently reported to regulate heparanase (HPSE) activity, a protumor enzyme involved cell migration and invasion, making them very promising molecules for new therapeutic applications. However, one of specific features commercial (λ-CAR) is that they heterogeneous mixtures different CAR families, named according thickening-purpose final-product viscosity which does not reflect real...