A5041958372- Lung Cancer Treatments and Mutations
- RNA modifications and cancer
- Lung Cancer Diagnosis and Treatment
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Lung Cancer Research Studies
- Cancer-related Molecular Pathways
- Advanced MRI Techniques and Applications
- Advanced NMR Techniques and Applications
- Atomic and Subatomic Physics Research
- Tracheal and airway disorders
- Ferroptosis and cancer prognosis
- Monoclonal and Polyclonal Antibodies Research
- Myasthenia Gravis and Thymoma
- Cancer, Stress, Anesthesia, and Immune Response
- Medical Imaging and Pathology Studies
- Inflammatory mediators and NSAID effects
- Cancer Treatment and Pharmacology
- Viral-associated cancers and disorders
- Cancer Genomics and Diagnostics
- Biological Research and Disease Studies
- Sarcoidosis and Beryllium Toxicity Research
- Lymphoma Diagnosis and Treatment
- Epigenetics and DNA Methylation
- ATP Synthase and ATPases Research
University of California, Berkeley
2025
University of California, San Francisco
2025
University of California System
2025
Institut Jules Bordet
2004-2019
Université Libre de Bruxelles
2004-2019
Centre Hospitalier Universitaire de Saint-Pierre
2005-2008
Leefmilieu Brussel
2006
Centre Hospitalier Régional et Universitaire de Nancy
2001
University Hospital of Zurich
1995
MicroRNAs, negative post-transcriptional regulators of gene expression, are involved in cancer. Their role early bronchial carcinogenesis was analysed 60 biopsies obtained by fluorescence bronchoscopy (six per stage: normal tissue nonsmokers, normofluorescent and hypofluorescent smokers, hyperplasia, metaplasia, mild, moderate severe dysplasia, situ carcinoma invasive squamous cell (SQCC)). In total, 69 microRNAs were found to be differentially expressed the course carcinogenesis. Among...
Positron emission tomography with 18F-fluoro-2-deoxy- d -glucose (FDG-PET) is more accurate than computed for staging of mediastinal (hilar) lymph nodes. In the case positive findings, tissue sampling nodes required. The diagnostic/staging yield transbronchial needle aspiration (TBNA) following endobronchial ultrasound (EBUS) localisation was assessed in this particular clinical setting. number avoided surgical procedures evaluated. All consecutive patients referred and/or diagnosis FDG-PET...
Abstract Purpose In this work, we adopt the MR fingerprinting (MRF) framework and leverage its flexibility in quantitative pulse sequence design to propose improved balanced steady‐state free precession (bSSFP)–based hyperpolarized Carbon‐13 ( 13 C) acquisitions for robust metabolic conversion rate quantification. Methods Spectrally selective bSSFP‐based with variable RF excitation were implemented [1‐ C]pyruvate used conjunction prior implementation of C]lactate bSSFP imaging. MRF parameter...
The efficacy and toxicity of combined paclitaxel gemcitabine was evaluated in 54 chemotherapy-naive patients with metastatic non-small cell lung cancer (NSCLC). Gemcitabine i.v. 1000 mg/m(2)was administered on days 1 8 200 mg/m(2)as a continuous 3-hour infusion day 1. Treatment repeated every 21 days. Patients had median age 53 years. ECOG performance status 0 or 48 patients. 41 (75.9%) initial stage IV disease; histology mainly adenocarcinoma (46.3%). 2 (4.3%) achieved complete response 15...
Murine double minute clone 2 (MDM2), p14 alternate reading frame (p14arf), and nucleophosmin (NPM) regulate p53 activity. A total of 200 biopsies, including normal bronchial, pre-invasive invasive tissues, were examined for changes in NPM, p14arf, MDM2 expression patterns by immunohistochemistry immunofluorescence with confocal microscopy. NPM p14arf displayed a diffuse nuclear staining most bronchial tissue. The fraction biopsies displaying an increased or nucleolar relocalisation at mild...
Epstein-Barr virus (EBV)-associated lymphoid proliferations that are similar to post-transplantation lymphoproliferative disorders may occasionally occur in the setting of human immunodeficiency (HIV) infection. Herein, we describe such a lesion involving adenoids HIV-seropositive adolescent who acquired immunity against EBV during childhood. On microscopic examination, marginal zone B follicles and interfollicular area were enlarged due accumulation small or intermediate-sized lymphocytes,...