A5077137206- Glutathione Transferases and Polymorphisms
- Pregnancy and preeclampsia studies
- Adenosine and Purinergic Signaling
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Gestational Trophoblastic Disease Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Biological Stains and Phytochemicals
- Apelin-related biomedical research
- Protease and Inhibitor Mechanisms
- Hormonal Regulation and Hypertension
- Cancer Cells and Metastasis
- Diabetes Treatment and Management
- Essential Oils and Antimicrobial Activity
- Sarcoma Diagnosis and Treatment
- Polyomavirus and related diseases
- Stress Responses and Cortisol
- Neural and Behavioral Psychology Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pregnancy and Medication Impact
- Folate and B Vitamins Research
- Oral and Maxillofacial Pathology
- Paraoxonase enzyme and polymorphisms
- Liver physiology and pathology
- Dermatoglyphics and Human Traits
Sağlık Bilimleri Üniversitesi
2025
Giresun University
2017-2024
Sivas Cumhuriyet Üniversitesi
2005-2007
Abstract This study aimed to evaluate the advantages and disadvantages of early versus delayed single-stage surgery in patients with hand enchondromas who developed pathological fractures, focusing on local tumor control function, determine optimal timing for surgery. Delayed surgical curettage may offer regarding both function outcomes. Thirty-five fractures due solitary underwent treatment between 2015 2021 were analysed. Patients divided into two groups based immediately after a fracture...
Abstract Aim: To assess the association between human epoxide hydrolase exon 3 and 4 polymorphisms pre‐eclampsia by carrying out a case‐control study in Turkish women. Methods: DNA was extracted from peripheral blood leukocytes, genotype distribution of gene ( EPHX ) carried 271 patients 155 controls. Results: There no statistically significant difference genotypes without HELLP plus cases controls for polymorphism . However, we found predicted enzyme activity level P = 0.018). The subjects...
Background Diabetic retinopathy (DR) occurs due to high blood glucose damage the retina and leads blindness if left untreated. KATP related genes (KCNJ11 ABCC8) play an important role in insulin secretion by glucose-stimulated pancreatic beta cells regulation of secretion. KCNJ11 E23K (rs5219), ABCC8–3 C/T (rs1799854), Thr759Thr (rs1801261) Arg1273Arg (rs1799859) are among possible single nucleotide polymorphisms (SNPs). The aim this study is find out how DR these SNPs associated with one...
Long non‑coding RNAs (lncRNAs) are molecules that >200 base pairs long and do not encode a protein. However, they perform important roles in regulating gene expression. Recent studies have revealed the changes expressions of lncRNAs serve role development metastases number types cancer. A been published on association SOX2 overlapping transcript (<em>SOX2OT</em>), differentiation antagonizing non‑protein coding RNA (<em>DANCR</em>) tissue differentiation‑induced (<em>TINCR</em>)...
There is substantial evidence that genetic factors play a role in pre-eclampsia. The aim of this study was to determine whether variability the encoding genes for glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) contributes individual differences susceptibility pre-eclampsia, eclampsia, or hemolysis, elevated liver enzymes, low platelets (HELLP syndrome).A total 221 women with eclampsia HELLP syndrome 147 healthy female controls were genotyped GSTM1 GSTT1 polymorphisms by polymerase chain...
Drug resistance poses a crucial problem in the treatment of prostate cancer. Recent studies have shown that chemotherapy agents may cause cancer cells to acquire stem cell-like properties, resulting drug and, eventually, failure.To evaluate whether long-term paclitaxel exposure causes an increase properties cells.Paclitaxel-resistant PC-3 were generated from parental by treating them with increasing concentrations paclitaxel. The expression levels cell markers NANOG, C-MYC, CD44, and ABCG2...
Long noncoding RNAs (lncRNAs) play an important role in regulating gene expression. Changes their expression have been associated with many types of cancer, including thyroid cancer. This study aimed to investigate how changes the potassium voltage-gated channel subfamily Q member 1 opposite strand/antisense transcript (KCNQ1OT1) and HAGLR strand lncRNA (HAGLROS) lncRNAs correlate development clinicopathological characteristics papillary cancer (PTC). Reverse transcription-quantitative...
The natural products derived from plants are the important sources that can be used for breast cancer treatment. Salvia species and their were recommended as potential antitumor substances.The cytotoxic genotoxic effects of kronenburgii have been investigated on cell lines, MCF-7 MDA-MB-231.Determination chemical compounds S. was done using a gas chromatography coupled to time-of-flight mass spectrometry system dual-stage commercial thermal desorption injector. Growth inhibition measured by...
Angiogenesis is the process by which new blood vessels are formed to meet oxygen and nutrient needs of tissues. This vitally important in many physiological pathological conditions such as tumor growth, metastasis, chronic inflammation. Although relationship FDI-6 compound with FOXM1 protein well known literature, its angiogenesis not adequately elucidated. study investigates vascular endothelial growth factor B (VEGF-B) expression alterations. Furthermore, aims elucidate silico interaction...
Background/aim: This study aims to investigate the association between rs2267437, rs5751129 and rs132770 polymorphisms of XRCC6 gene, which plays a role in repairing DNA double strand breaks, risk Papillary Thyroid Cancer (PTC).Methods: The included 150 patients who had been diagnosed with PTC 204 healthy control subjects. Genotyping SNPs was performed by Polymerase Chain Reaction - Restriction Fragment Length Polymorphism method (PCR RFLP).Results: In rs2267437 polymorphism, individuals GG...
Aim: Diabetes mellitus (DM) is an important health problem with increasing incidence worldwide and causes many complications. Diabetic retinopathy (DR) one of the most serious complications DM. Polymorphisms AKR1B1 gene, which encodes aldose reductase enzyme, have been associated development DM DR in some studies. The current study aims to investigate relationship rs759853 polymorphism type 2 (T2DM), severity Turkish population. Materials Methods: A total 437 individuals, including 141 T2DM...
Objective: The pathological mechanisms of gestational trophoblastic disease have not yet been clearly determined. It is thought that oxidative damage contributes to the process. aim this study was determine levels coenzyme Q10 (CoQ10), DNA damage, and lipid peroxidation in patients with hydatidiform mole. Materials Methods: authors studied CoQ10, 8-hydroxydeoxyguanosine (8-OHdG), malondialdehyde (MDA) by high-performance liquid chromatography (HPLC), activity glutathione peroxidase (GPX)...
Monthly hormonal fluctuation in women causes changes peripheral systems and central nervous system structure functions. In this study, we investigated the effects of menstrual cycle periods on attention during multitasking. Single dual task conditions were tested different periods.A total forty with regular cycles participated study. They not any type medication or treatment. Fine motor skills Go/No-go tasks performed 10th day late follicular phase, then tests repeated 20th luteal phase. by...
Objective
 Type 2 diabetes mellitus (T2DM) and diabetic
 retinopathy (DR) development is affected by genetic
 factors. Matrix metalloproteinases (MMPs) are involved
 in many cellular processes, such as remodeling of
 extracellular matrix proteins angiogenesis. In
 this study, we investigated the relationship between
 MMP9 −1562 C/T (rs3918242) polymorphism the
 of T2DM DR Turkish population.
 Material Method
 A total 510 participants,...
10th International Congress on Psychopharmacology & 6th Symposium Child and Adolescent Psychopharmacology[Abstract:0110] [Addiction]Cessation of cigarette smoking in adolescents: s...